| Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot–peptide conjugates IL Medintz, AR Clapp, FM Brunel, T Tiefenbrunn, HT Uyeda, EL Chang, ... Nature materials 5 (7), 581-589, 2006 | 646 | 2006 |
| Two‐Photon Excitation of Quantum‐Dot‐Based Fluorescence Resonance Energy Transfer and Its Applications AR Clapp, T Pons, IL Medintz, JB Delehanty, JS Melinger, T Tiefenbrunn, ... Advanced Materials 19 (15), 1921-1926, 2007 | 140 | 2007 |
| High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment T Tiefenbrunn, W Liu, Y Chen, V Katritch, CD Stout, JA Fee, V Cherezov PLoS One 6 (7), e22348, 2011 | 138 | 2011 |
| Chemoselective ligation techniques: Modern applications of time‐honored chemistry TK Tiefenbrunn, PE Dawson Peptide Science 94 (1), 95-106, 2010 | 98 | 2010 |
| Distinguishing Binders from False Positives by Free Energy Calculations: Fragment Screening Against the Flap Site of HIV Protease N Deng, S Forli, P He, A Perryman, L Wickstrom, RSK Vijayan, ... The Journal of Physical Chemistry B 119 (3), 976-988, 2014 | 66 | 2014 |
| Crystallographic Fragment‐Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease T Tiefenbrunn, S Forli, M Happer, A Gonzalez, Y Tsai, M Soltis, JH Elder, ... Chemical biology & drug design 83 (2), 141-148, 2014 | 48 | 2014 |
| Small molecule regulation of protein conformation by binding in the flap of HIV protease T Tiefenbrunn, S Forli, MM Baksh, MW Chang, M Happer, YC Lin, ... ACS chemical biology 8 (6), 1223-1231, 2013 | 39 | 2013 |
| AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery Y Tsai, SE McPhillips, A González, TM McPhillips, D Zinn, AE Cohen, ... Acta Crystallographica Section D: Biological Crystallography 69 (5), 796-803, 2013 | 24 | 2013 |
| Alternative chemistries for the synthesis of thrombospondin‐1 type 1 repeats TK Tiefenbrunn, J Blanco‐Canosa, PE Dawson Peptide Science 94 (4), 405-413, 2010 | 18 | 2010 |
| Towards novel therapeutics for HIV through fragment-based screening and drug design T Tiefenbrunn, CD Stout Progress in biophysics and molecular biology 116 (2), 124-140, 2014 | 8 | 2014 |
| Chemical synthesis and biotinylation of the thrombospondin domain TSR2 TK Tiefenbrunn, PE Dawson Protein Science 18 (5), 970-979, 2009 | 7 | 2009 |
| Manipulation of thrombin exosite I, by ligand‐directed covalent modification S Yegneswaran, TK Tiefenbrunn, JA Fernandez, PE Dawson Journal of Thrombosis and Haemostasis 5 (10), 2062-2069, 2007 | 5 | 2007 |
| Synthesis and Site-directed Labeling of Proteins: Using Unnatural Amino Acids to Probe Structure and Function; a Thesis Presented TK Tiefenbrunn Scripps Research Institute, La Jolla, California, 2009 | | 2009 |
| Exosite-Specific Inhibition of Thrombin Using Photo-Crosslinked Fluorescent Reporter Peptides. S Yegneswaran, T Tiefenbrunn, JA Fernandez, PE Dawson Blood 106 (11), 1954-1954, 2005 | | 2005 |
