| Reprogramming to recover youthful epigenetic information and restore vision Y Lu, B Brommer, X Tian, A Krishnan, M Meer, C Wang, DL Vera, Q Zeng, ... Nature 588 (7836), 124-129, 2020 | 530 | 2020 |
| Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging A Das, GX Huang, MS Bonkowski, A Longchamp, C Li, MB Schultz, ... Cell 173 (1), 74-89. e20, 2018 | 390 | 2018 |
| Loss of epigenetic information as a cause of mammalian aging JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ... Cell 186 (2), 305-326. e27, 2023 | 244 | 2023 |
| Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging A Das, GX Huang, MS Bonkowski, A Longchamp, C Li, MB Schultz, ... Cell 176 (4), 944-945, 2019 | 42 | 2019 |
| Reversal of ageing-and injury-induced vision loss by Tet-dependent epigenetic reprogramming Y Lu, A Krishnan, B Brommer, X Tian, M Meer, DL Vera, C Wang, Q Zeng, ... BioRxiv, 710210, 2019 | 26 | 2019 |
| Gene Therapy-Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice CC Macip, R Hasan, V Hoznek, J Kim, YR Lu, LE Metzger IV, S Sethna, ... Cellular Reprogramming 26 (1), 24-32, 2024 | 19 | 2024 |
| Molecular and cellular characterization of SIRT1 allosteric activators MB Schultz, C Rinaldi, Y Lu, JA Amorim, DA Sinclair Protein Acetylation: Methods and Protocols, 133-149, 2019 | 17 | 2019 |
| Spateo: multidimensional spatiotemporal modeling of single-cell spatial transcriptomics X Qiu, DY Zhu, J Yao, Z Jing, L Zuo, M Wang, KH Min, H Pan, S Wang, ... BioRxiv, 2022.12. 07.519417, 2022 | 11 | 2022 |
| The information theory of aging YR Lu, X Tian, DA Sinclair Nature Aging 3 (12), 1486-1499, 2023 | 10 | 2023 |
| Assays for NAD+-Dependent Reactions and NAD+ Metabolites MB Schultz, Y Lu, N Braidy, DA Sinclair ADP-ribosylation and NAD+ Utilizing Enzymes: Methods and Protocols, 77-90, 2018 | 8 | 2018 |
| Sustained vision recovery by OSK gene therapy in a mouse model of glaucoma MM Karg, YR Lu, N Refaian, J Cameron, E Hoffmann, C Hoppe, ... Cellular Reprogramming 25 (6), 288-299, 2023 | 5 | 2023 |
| Epigenetic reprogramming-A novel gene therapy that restores vision loss in a nonhuman primate model of NAION B Ksander, M Shah, D Krasniqi, MS Gregory-Ksander, ... Investigative Ophthalmology & Visual Science 64 (8), 474-474, 2023 | 4 | 2023 |
| The Role of Epigenetics in Accelerated Aging: A Reconsideration of Later-Life Visual Loss After Early Optic Neuropathy JF Rizzo 3rd, MP Shah, D Krasniqi, YR Lu, DA Sinclair, BR Ksander Journal of neuro-ophthalmology: the official journal of the North American …, 2023 | 2* | 2023 |
| Loss of Epigenetic Information as a Cause of Mammalian Aging JH Yang, M Hayano, P Griffin, JA Amorim, MS Bonkowski, JK Apostolides, ... | 2 | 2021 |
| Reversal of aging-induced and glaucoma-induced vision loss by in vivo epigenetic reprogramming B Ksander, Y Lu, A Krishnan, B Brommer, X Tian, M Meer, D Vera, ... Investigative Ophthalmology & Visual Science 61 (7), 2364-2364, 2020 | 2 | 2020 |
| In vivo cellular reprogramming for tissue regeneration and age reversal Y Lu, D Yu, M Bonkowski, M Schultz, X Tian, J Yang, Z He, D Sinclair Innovation in Aging 2 (Suppl 1), 883, 2018 | 2 | 2018 |
| 动物隐花色素研究进展 吕垣澄， 吴晓晖 遗传 36 (9), 864-870, 2014 | 2 | 2014 |
| Non-human primate laser-induced NAION model for assessing neuro-rejuvenating gene therapies M Shah, D Krasniqi, MS Gregory-Ksander, S Rosenzweig-Lipson, ... Investigative Ophthalmology & Visual Science 64 (8), 5223-5223, 2023 | 1 | 2023 |
| Mutant reverse tetracycline transactivators for expression of genes DA Sinclair, Y Lu, NJ DAVIDSOHN | 1 | 2021 |
| In vivo epigenetic reprogramming reverses the age-induced morphological decline of retinal pigment epithelial cells M Karg, Y Lu, E Hoffmann, H Philipose, D Sinclair, B Ksander, ... Investigative Ophthalmology & Visual Science 62 (8), 3283-3283, 2021 | 1 | 2021 |
David A. SinclairHarvard Medical School (Genetics)Verified email at hms.harvard.edu
