| Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by … P Schmiedlin-Ren, DJ Edwards, ME Fitzsimmons, K He, KS Lown, ... Drug Metabolism and Disposition 25 (11), 1228-1233, 1997 | 487 | 1997 |
| Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice K He, KR Iyer, RN Hayes, MW Sinz, TF Woolf, PF Hollenberg Chemical research in toxicology 11 (4), 252-259, 1998 | 415 | 1998 |
| Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases C Sridar, TC Goosen, UM Kent, JA Williams, PF Hollenberg Drug metabolism and disposition 32 (6), 587-594, 2004 | 290 | 2004 |
| Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes PF Hollenberg Drug metabolism reviews 34 (1-2), 17-35, 2002 | 290 | 2002 |
| A nonsynchronous concerted mechanism for cytochrome P-450 catalyzed hydroxylation M Newcomb, MH Le Tadic-Biadatti, DL Chestney, ES Roberts, ... Journal of the American Chemical Society 117 (49), 12085-12091, 1995 | 284 | 1995 |
| Cytochrome P450-catalyzed hydroxylation of mechanistic probes that distinguish between radicals and cations. Evidence for cationic but not for radical intermediates M Newcomb, R Shen, SY Choi, PH Toy, PF Hollenberg, ADN Vaz, ... Journal of the American Chemical Society 122 (12), 2677-2686, 2000 | 271 | 2000 |
| The use of intramolecular isotope effects to distinguish between deprotonation and hydrogen atom abstraction mechanisms in cytochrome P-450-and peroxidase-catalyzed N … GT Miwa, JS Walsh, GL Kedderis, PF Hollenberg Journal of Biological Chemistry 258 (23), 14445-14449, 1983 | 241 | 1983 |
| Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands KC Chimalakonda, KA Seely, SM Bratton, LK Brents, CL Moran, ... Drug metabolism and disposition 40 (11), 2174-2184, 2012 | 220 | 2012 |
| Role of the alanine at position 363 of cytochrome P450 2B2 in influencing the NADPH-and hydroperoxide-supported activities IH Hanna, JF Teiber, KL Kokones, PF Hollenberg Archives of Biochemistry and Biophysics 350 (2), 324-332, 1998 | 219 | 1998 |
| Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations M Newcomb, PF Hollenberg, MJ Coon Archives of biochemistry and biophysics 409 (1), 72-79, 2003 | 200 | 2003 |
| The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9 UM Kent, M Aviram, M Rosenblat, PF Hollenberg Drug metabolism and disposition 30 (6), 709-715, 2002 | 197 | 2002 |
| Mechanism-based inactivation of human cytochromes p450s: experimental characterization, reactive intermediates, and clinical implications PF Hollenberg, UM Kent, NN Bumpus Chemical research in toxicology 21 (1), 189-205, 2008 | 191 | 2008 |
| The effects of dietary ellagic acid on rat hepatic and esophageal mucosal cytochromes P450 and phase II enzymes D Ahn, D Putt, L Kresty, GD Stoner, D Fromm, PF Hollenberg Oxford University Press 17 (4), 821-828, 1996 | 190 | 1996 |
| Mechanism-based inactivators as probes of cytochrome P450 structure and function UM Kent, MI Jushchhyshyn, PF Hollenberg Current drug metabolism 2 (3), 215-243, 2001 | 171 | 2001 |
| Subunit structure of rabbit muscle pyruvate kinase GL Cottam, PF Hollenberg, MJ Coon Journal of Biological Chemistry 244 (6), 1481-1486, 1969 | 169 | 1969 |
| The P-450 nature of the carbon monoxide complex of ferrous chloroperoxidase PF Hollenberg, LP Hager Journal of Biological Chemistry 248 (7), 2630-2633, 1973 | 157 | 1973 |
| Mechanism-based inactivation of cytochrome P450 3A4 by 17α-ethynylestradiol: evidence for heme destruction and covalent binding to protein H Lin, UM Kent, PF Hollenberg Journal of Pharmacology and Experimental Therapeutics 301 (1), 160-167, 2002 | 155 | 2002 |
| Expression of human cytochrome P450 2B6 in Escherichia coli: characterization of catalytic activity and expression levels in human liver IH Hanna, JR Reed, FP Guengerich, PF Hollenberg Archives of Biochemistry and Biophysics 376 (1), 206-216, 2000 | 153 | 2000 |
| Mechanisms of cytochrome P450 and peroxidase‐catalyzed xenobiotic metabolism PF Hollenberg The FASEB journal 6 (2), 686-694, 1992 | 150 | 1992 |
| Regiochemical variations in reactions of methylcubane with tert-butoxyl radical, cytochrome P-450 enzymes, and a methane monooxygenase system SY Choi, PE Eaton, PF Hollenberg, KE Liu, SJ Lippard, M Newcomb, ... Journal of the American Chemical Society 118 (28), 6547-6555, 1996 | 139 | 1996 |
