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Kynan Lawlor
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Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation
KT Lawlor, JM Vanslambrouck, JW Higgins, A Chambon, K Bishard, ...
Nature materials 20 (2), 260-271, 2021
2742021
Evaluation of variability in human kidney organoids
B Phipson, PX Er, AN Combes, TA Forbes, SE Howden, L Zappia, HJ Yen, ...
Nature methods 16 (1), 79-87, 2019
2032019
3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening
LJ Hale, SE Howden, B Phipson, A Lonsdale, PX Er, I Ghobrial, S Hosawi, ...
Nature communications 9 (1), 5167, 2018
1922018
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype and reveal underlying pathogenetic mechanisms
TA Forbes, SE Howden, K Lawlor, B Phipson, J Maksimovic, L Hale, ...
The American Journal of Human Genetics 102 (5), 816-831, 2018
1762018
Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk
AN Combes, B Phipson, KT Lawlor, A Dorison, R Patrick, L Zappia, ...
Development 146 (12), dev178673, 2019
1362019
Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells
SV Kumar, PX Er, KT Lawlor, A Motazedian, M Scurr, I Ghobrial, ...
Development 146 (5), dev172361, 2019
1092019
Dermal contributions to human interfollicular epidermal architecture and self-renewal
KT Lawlor, P Kaur
International journal of molecular sciences 16 (12), 28098-28107, 2015
672015
Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases
KT Lawlor, LV O'Keefe, SE Samaraweera, CL van Eyk, CJ McLeod, ...
Human Molecular Genetics 20 (19), 3757-3768, 2011
582011
Nephron progenitor commitment is a stochastic process influenced by cell migration
KT Lawlor, L Zappia, J Lefevre, JS Park, NA Hamilton, A Oshlack, ...
Elife 8, e41156, 2019
492019
Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs
CL Van Eyk, LV O'Keefe, KT Lawlor, SE Samaraweera, CJ McLeod, ...
Human molecular genetics 20 (14), 2783-2794, 2011
352011
Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids
JM Vanslambrouck, SB Wilson, KS Tan, E Groenewegen, R Rudraraju, ...
Nature Communications 13 (1), 5943, 2022
322022
Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number
AN Combes, S Wilson, B Phipson, BB Binnie, A Ju, KT Lawlor, C Cebrian, ...
Kidney international 93 (3), 589-598, 2018
322018
Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening
JW Higgins, A Chambon, K Bishard, A Hartung, D Arndt, J Brugnano, ...
bioRxiv, 505396, 2018
252018
Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions
L Zhuang, KT Lawlor, H Schlueter, Z Pieterse, Y Yu, P Kaur
Life Science Alliance 1 (4), 2018
222018
High throughput single cell RNA-seq of developing mouse kidney and human kidney organoids reveals a roadmap for recreating the kidney
AN Combes, B Phipson, L Zappia, KT Lawlor, PX Er, A Oshlack, MH Little
BioRXIV, 235499, 2017
132017
Correction: Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk (doi: 10.1242/dev. 178673)
AN Combes, B Phipson, KT Lawlor, A Dorison, R Patrick, L Zappia, ...
Development 146 (13), dev182162, 2019
122019
Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology
KT Lawlor, LV O’Keefe, SE Samaraweera, CL Van Eyk, RI Richards
PLoS One 7 (6), e38516, 2012
122012
Drosophila Dachsous and Fat polarize actin-based protrusions over a restricted domain of the embryonic denticle field
KT Lawlor, DC Ly, S DiNardo
Developmental biology 383 (2), 285-294, 2013
112013
Recreating, expanding and using nephron progenitor populations
MH Little, KT Lawlor
Nature Reviews Nephrology 16 (2), 75-76, 2020
92020
Kidney organoids generated using an allelic series of NPHS2 point variants reveal distinct intracellular podocin mistrafficking
A Dorison, I Ghobrial, A Graham, T Peiris, TA Forbes, M See, M Das, ...
Journal of the American Society of Nephrology 34 (1), 88-109, 2023
82023
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