|Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype and reveal underlying pathogenetic mechanisms|
TA Forbes, SE Howden, K Lawlor, B Phipson, J Maksimovic, L Hale, ...
The American Journal of Human Genetics 102 (5), 816-831, 2018
|Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases|
KT Lawlor, LV O'Keefe, SE Samaraweera, CL van Eyk, CJ McLeod, ...
Human molecular genetics 20 (19), 3757-3768, 2011
|Evaluation of variability in human kidney organoids|
B Phipson, XE Pei, AN Combes, TA Forbes, SE Howden, L Zappia, ...
Nature methods 16 (1), 79-87, 2019
|3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening|
LJ Hale, SE Howden, B Phipson, A Lonsdale, XE Pei, I Ghobrial, ...
Nature communications 9 (1), 1-17, 2018
|Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs|
CL Van Eyk, LV O'Keefe, KT Lawlor, SE Samaraweera, CJ McLeod, ...
Human molecular genetics 20 (14), 2783-2794, 2011
|Dermal contributions to human interfollicular epidermal architecture and self-renewal|
KT Lawlor, P Kaur
International journal of molecular sciences 16 (12), 28098-28107, 2015
|Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk|
AN Combes, B Phipson, KT Lawlor, A Dorison, R Patrick, L Zappia, ...
Development 146 (12), dev178673, 2019
|Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number|
AN Combes, S Wilson, B Phipson, BB Binnie, A Ju, KT Lawlor, C Cebrian, ...
Kidney international 93 (3), 589-598, 2018
|Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells|
SV Kumar, XE Pei, KT Lawlor, A Motazedian, M Scurr, I Ghobrial, ...
Development 146 (5), dev172361, 2019
|Nephron progenitor commitment is a stochastic process influenced by cell migration|
KT Lawlor, L Zappia, J Lefevre, JS Park, NA Hamilton, A Oshlack, ...
Elife 8, e41156, 2019
|High throughput single cell RNA-seq of developing mouse kidney and human kidney organoids reveals a roadmap for recreating the kidney|
AN Combes, B Phipson, L Zappia, KT Lawlor, PX Er, A Oshlack, MH Little
bioRxiv, 235499, 2017
|Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology|
KT Lawlor, LV O’Keefe, SE Samaraweera, CL Van Eyk, RI Richards
PLoS One 7 (6), 2012
|Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening.|
JW Higgins, A Chambon, K Bishard, A Hartung, D Arndt, J Brugnano, ...
bioRxiv, 505396, 2018
|Drosophila Dachsous and Fat polarize actin-based protrusions over a restricted domain of the embryonic denticle field|
KT Lawlor, DC Ly, S DiNardo
Developmental biology 383 (2), 285-294, 2013
|Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions|
L Zhuang, KT Lawlor, H Schlueter, Z Pieterse, Y Yu, P Kaur
Life science alliance 1 (4), 2018
|Transcriptional evaluation of the developmental accuracy, reproducibility and robustness of kidney organoids derived from human pluripotent stem cells|
B Phipson, PX Er, L Hale, D Yen, K Lawlor, M Takasato, J Sun, ...
bioRxiv, 238428, 2017
|Modeling and Analysis of Repeat RNA Toxicity in Drosophila|
SE Samaraweera, LV O’Keefe, CL van Eyk, KT Lawlor, DT Humphreys, ...
Tandem Repeats in Genes, Proteins, and Disease, 173-192, 2013
|Recreating, expanding and using nephron progenitor populations|
MH Little, KT Lawlor
Nature Reviews Nephrology 16 (2), 75-76, 2020