Insights into RNA biology from an atlas of mammalian mRNA-binding proteins A Castello, B Fischer, K Eichelbaum, R Horos, BM Beckmann, C Strein, ... Cell 149 (6), 1393-1406, 2012 | 2255 | 2012 |
Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA JE Squires, HR Patel, M Nousch, T Sibbritt, DT Humphreys, BJ Parker, ... Nucleic acids research 40 (11), 5023-5033, 2012 | 1002 | 2012 |
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly (A) tail function DT Humphreys, BJ Westman, DIK Martin, T Preiss Proceedings of the National Academy of Sciences 102 (47), 16961-16966, 2005 | 956 | 2005 |
Clusterin has chaperone-like activity similar to that of small heat shock proteins DT Humphreys, JA Carver, SB Easterbrook-Smith, MR Wilson Journal of Biological Chemistry 274 (11), 6875-6881, 1999 | 550 | 1999 |
Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells CCY Li, SA Eaton, PE Young, M Lee, R Shuttleworth, DT Humphreys, ... RNA biology 10 (8), 1333-1344, 2013 | 279 | 2013 |
Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-β N Schonrock, YD Ke, D Humphreys, M Staufenbiel, LM Ittner, T Preiss, ... PloS one 5 (6), e11070, 2010 | 267 | 2010 |
NAD deficiency, congenital malformations, and niacin supplementation H Shi, A Enriquez, M Rapadas, EMMA Martin, R Wang, J Moreau, CK Lim, ... New England Journal of Medicine 377 (6), 544-552, 2017 | 249 | 2017 |
Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β N Schonrock, DT Humphreys, T Preiss, J Götz Journal of Molecular Neuroscience 46, 324-335, 2012 | 187 | 2012 |
Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity JE Cropley, SA Eaton, A Aiken, PE Young, E Giannoulatou, JWK Ho, ... Molecular metabolism 5 (8), 699-708, 2016 | 173 | 2016 |
The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells SP Keam, PE Young, AL McCorkindale, THY Dang, JL Clancy, ... Nucleic acids research 42 (14), 8984-8995, 2014 | 150 | 2014 |
microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells TH Beilharz, DT Humphreys, JL Clancy, R Thermann, DIK Martin, ... PloS one 4 (8), e6783, 2009 | 150 | 2009 |
Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction V Janbandhu, V Tallapragada, R Patrick, Y Li, D Abeygunawardena, ... Cell Stem Cell 29 (2), 281-297. e12, 2022 | 128 | 2022 |
Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function DT Humphreys, CJ Hynes, HR Patel, GH Wei, L Cannon, D Fatkin, ... PloS one 7 (2), e30933, 2012 | 105 | 2012 |
Effects of clusterin overexpression on TNFα-and TGFβ-mediated death of L929 cells D Humphreys, TT Hochgrebe, SB Easterbrook-Smith, MP Tenniswood, ... Biochemistry 36 (49), 15233-15243, 1997 | 104 | 1997 |
Verification and validation of bioinformatics software without a gold standard: a case study of BWA and Bowtie E Giannoulatou, SH Park, DT Humphreys, JWK Ho BMC bioinformatics 15, 1-8, 2014 | 95 | 2014 |
A screening approach to identify clinically actionable variants causing congenital heart disease in exome data JO Szot, H Cuny, GM Blue, DT Humphreys, E Ip, K Harrison, GF Sholler, ... Circulation: Genomic and Precision Medicine 11 (3), e001978, 2018 | 87 | 2018 |
Identification of clinically actionable variants from genome sequencing of families with congenital heart disease D Alankarage, E Ip, JO Szot, J Munro, GM Blue, K Harrison, H Cuny, ... Genetics in Medicine 21 (5), 1111-1120, 2019 | 80 | 2019 |
Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis B Liang, M Soka, AH Christensen, MS Olesen, AP Larsen, FK Knop, ... Journal of Molecular and Cellular Cardiology 67, 69-76, 2014 | 79 | 2014 |
Modes of L929 cell death induced by TNF-α and other cytotoxic agents DT Humphreys, MR Wilson Cytokine 11 (10), 773-782, 1999 | 77 | 1999 |
Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data R Patrick, DT Humphreys, V Janbandhu, A Oshlack, JWK Ho, RP Harvey, ... Genome biology 21, 1-27, 2020 | 76 | 2020 |