|Guidelines for the use and interpretation of assays for monitoring autophagy|
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 8 (4), 445-544, 2012
|Apoptosis, p53, and tumor cell sensitivity to anticancer agents|
JM Brown, BG Wouters
Cancer research 59 (7), 1391-1399, 1999
|Hypoxia signalling through mTOR and the unfolded protein response in cancer|
BG Wouters, M Koritzinsky
Nature Reviews Cancer 8 (11), 851-864, 2008
|Towards the introduction of the ‘Immunoscore’in the classification of malignant tumours|
J Galon, B Mlecnik, G Bindea, HK Angell, A Berger, C Lagorce, A Lugli, ...
The Journal of pathology 232 (2), 199-209, 2014
|ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth|
M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ...
The EMBO journal 24 (19), 3470-3481, 2005
|Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α|
C Koumenis, C Naczki, M Koritzinsky, S Rastani, A Diehl, N Sonenberg, ...
Molecular and cellular biology 22 (21), 7405-7416, 2002
|The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5|
KMA Rouschop, T Van Den Beucken, L Dubois, H Niessen, J Bussink, ...
The Journal of clinical investigation 120 (1), 127-141, 2010
|Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells|
TN Seagroves, HE Ryan, H Lu, BG Wouters, M Knapp, P Thibault, ...
Molecular and cellular biology 21 (10), 3436-3444, 2001
|Cancer classification using the Immunoscore: a worldwide task force|
J Galon, F Pagès, FM Marincola, HK Angell, M Thurin, A Lugli, I Zlobec, ...
Journal of translational medicine 10 (1), 1-10, 2012
|International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study|
F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou, C Bifulco, A Lugli, ...
The Lancet 391 (10135), 2128-2139, 2018
|Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis|
JC Sluimer, JM Gasc, JL van Wanroij, N Kisters, M Groeneweg, ...
Journal of the American College of Cardiology 51 (13), 1258-1265, 2008
|Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and-Independent Mechanisms and Contributes to Drug Resistance|
JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ...
Molecular and Cellular Biology 24 (7), 2875-2889, 2004
|Activating transcription factor 4 is translationally regulated by hypoxic stress|
JD Blais, V Filipenko, M Bi, HP Harding, D Ron, C Koumenis, BG Wouters, ...
Molecular and cellular biology 24 (17), 7469-7482, 2004
|Cells at intermediate oxygen levels can be more important than the" hypoxic fraction" in determining tumor response to fractionated radiotherapy|
BG Wouters, JM Brown
Radiation research 147 (5), 541-550, 1997
|Time between the first day of chemotherapy and the last day of chest radiation is the most important predictor of survival in limited-disease small-cell lung cancer|
D De Ruysscher, M Pijls-Johannesma, SM Bentzen, A Minken, ...
J Clin Oncol 24 (7), 1057-1063, 2006
|Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control|
M Koritzinsky, MG Magagnin, T van den Beucken, R Seigneuric, ...
The EMBO journal 25 (5), 1114-1125, 2006
|Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance|
N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ...
Cancer research 68 (2), 605-614, 2008
|Low-dose hyper-radiosensitivity: a consequence of ineffective cell cycle arrest of radiation-damaged G2-phase cells|
B Marples, BG Wouters, SJ Collis, AJ Chalmers, MC Joiner
Radiation research 161 (3), 247-255, 2004
|Hypoxia as a target for combined modality treatments|
BG Wouters, SA Weppler, M Koritzinsky, W Landuyt, S Nuyts, J Theys, ...
European Journal of Cancer 38 (2), 240-257, 2002
|“Translating” Tumor Hypoxia: Unfolded Protein Response (UPR)–Dependent and UPR-Independent Pathways|
C Koumenis, BG Wouters
Molecular Cancer Research 4 (7), 423-436, 2006