Andrew Grierson
Andrew Grierson
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Role of Axonal Transport in Neurodegenerative Diseases*
KJ De Vos, AJ Grierson, S Ackerley, CCJ Miller
Annu. Rev. Neurosci. 31, 151-173, 2008
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis
L Ferraiuolo, J Kirby, AJ Grierson, M Sendtner, PJ Shaw
Nature Reviews Neurology 7 (11), 616-630, 2011
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ...
Human molecular genetics 16 (22), 2720-2728, 2007
Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission
KJ De Vos, VJ Allan, AJ Grierson, MP Sheetz
Current biology 15 (7), 678-683, 2005
The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy
CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ...
The EMBO Journal, e201694401, 2016
Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy
CF Valori, K Ning, M Wyles, RJ Mead, AJ Grierson, PJ Shaw, M Azzouz
Science translational medicine 2 (35), 35ra42-35ra42, 2010
Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)
LE Cox, L Ferraiuolo, EF Goodall, PR Heath, A Higginbottom, H Mortiboys, ...
PLoS One 5 (3), e9872, 2010
Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments
S Ackerley, P Thornhill, AJ Grierson, J Brownlees, BH Anderton, PN Leigh, ...
The Journal of cell biology 161 (3), 489-495, 2003
Charcot–Marie–Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport
J Brownlees, S Ackerley, AJ Grierson, NJO Jacobsen, K Shea, ...
Human molecular genetics 11 (23), 2837-2844, 2002
Glutamate slows axonal transport of neurofilaments in transfected neurons
S Ackerley, AJ Grierson, J Brownlees, P Thornhill, BH Anderton, PN Leigh, ...
The Journal of cell biology 150 (1), 165-176, 2000
Parkinson's disease α-synuclein mutations exhibit defective axonal transport in cultured neurons
AR Saha, J Hill, MA Utton, AA Asuni, S Ackerley, AJ Grierson, CC Miller, ...
J Cell Sci 117 (7), 1017-1024, 2004
Phosphorylation of thr668 in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress‐activated protein kinase 1b (Jun N‐terminal kinase‐3)
CL Standen, J Brownlees, AJ Grierson, S Kesavapany, KF Lau, ...
Journal of neurochemistry 76 (1), 316-320, 2001
p38α stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis
S Ackerley, AJ Grierson, S Banner, MS Perkinton, J Brownlees, HL Byers, ...
Molecular and Cellular Neuroscience 26 (2), 354-364, 2004
Hereditary spastic paraparesis: disrupted intracellular transport associated with spastin mutation
CJ McDermott, AJ Grierson, JD Wood, M Bingley, SB Wharton, K Bushby, ...
Annals of neurology 54 (6), 748-759, 2003
Direct evidence for axonal transport defects in a novel mouse model of mutant spastin‐induced hereditary spastic paraplegia (HSP) and human HSP patients
PR Kasher, KJ De Vos, SB Wharton, C Manser, EJ Bennett, M Bingley, ...
Journal of neurochemistry 110 (1), 34-44, 2009
Axonal transport of neurofilaments in normal and disease states
CCJ Miller, S Ackerley, J Brownlees, AJ Grierson, NJO Jacobsen, ...
Cellular and Molecular Life Sciences CMLS 59 (2), 323-330, 2002
The cellular and molecular pathology of the motor system in hereditary spastic paraparesis due to mutation of the spastin gene
SB Wharton, CJ McDermott, AJ Grierson, JD Wood, C Gelsthorpe, ...
Journal of Neuropathology & Experimental Neurology 62 (11), 1166-1177, 2003
Selective loss of neurofilament expression in Cu/Zn superoxide dismutase (SOD1) linked amyotrophic lateral sclerosis
FM Menzies, AJ Grierson, MR Cookson, PR Heath, J Tomkins, ...
Journal of neurochemistry 82 (5), 1118-1128, 2002
Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis
LM Duffy, AL Chapman, PJ Shaw, AJ Grierson
Neuropathology and applied neurobiology 37 (4), 336-352, 2011
Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)
RJ Mead, EJ Bennett, AJ Kennerley, P Sharp, C Sunyach, P Kasher, ...
PloS one 6 (8), e23244, 2011
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