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Mitchell Lawrence
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Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression
H Hugo, ML Ackland, T Blick, MG Lawrence, JA Clements, ED Williams, ...
Journal of cellular physiology 213 (2), 374-383, 2007
13152007
Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling
R Pidsley, E Zotenko, TJ Peters, MG Lawrence, GP Risbridger, P Molloy, ...
Genome biology 17 (1), 208, 2016
7162016
Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus
MG Lawrence, J Lai, JA Clements
Endocrine reviews 31 (4), 407-446, 2010
2662010
Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer …
TL Veveris-Lowe, MG Lawrence, RL Collard, L Bui, AC Herington, ...
Endocrine-related cancer 12 (3), 631-643, 2005
1782005
Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories
RA Taylor, M Fraser, J Livingstone, SMG Espiritu, H Thorne, V Huang, ...
Nature communications 8 (1), 1-10, 2017
1772017
Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells
MG Lawrence, NV Margaryan, D Loessner, A Collins, KM Kerr, M Turner, ...
The Prostate 71 (11), 1198-1209, 2011
1162011
Patient-derived Xenografts Reveal that Intraductal Carcinoma of the Prostate Is a Prominent Pathology in BRCA2 Mutation Carriers with Prostate Cancer and …
GP Risbridger, RA Taylor, D Clouston, A Sliwinski, H Thorne, S Hunter, ...
European urology 67 (3), 496-503, 2015
1102015
A preclinical xenograft model of prostate cancer using human tumors
MG Lawrence, RA Taylor, R Toivanen, J Pedersen, S Norden, DW Pook, ...
Nature protocols 8 (5), 836, 2013
1022013
Enduring epigenetic landmarks define the cancer microenvironment
R Pidsley, MG Lawrence, E Zotenko, B Niranjan, A Statham, J Song, ...
Genome research 28 (5), 625-638, 2018
722018
A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer
AK Clark, AV Taubenberger, RA Taylor, B Niranjan, ZY Chea, E Zotenko, ...
Biomaterials 34 (20), 4777-4785, 2013
682013
Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy
MG Lawrence, D Obinata, S Sandhu, LA Selth, SQ Wong, LH Porter, ...
European urology 74 (5), 562-572, 2018
662018
Systematic review links the prevalence of intraductal carcinoma of the prostate to prostate cancer risk categories
LH Porter, MG Lawrence, D Ilic, D Clouston, DM Bolton, M Frydenberg, ...
European urology 72 (4), 492-495, 2017
652017
A community-based model of rapid autopsy in end-stage cancer patients.
K Alsop, H Thorne, S Sandhu, A Hamilton, C Mintoff, E Christie, O Spruyt, ...
Nature biotechnology 34 (10), 1010, 2016
612016
The role of kallikrein-related peptidases in prostate cancer: potential involvement in an epithelial to mesenchymal transition
AK Whitbread, TL Veveris-Lowe, MG Lawrence, DL Nicol, JA Clements
Biological chemistry 387 (6), 707-714, 2006
522006
Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment
EV Nguyen, BA Pereira, MG Lawrence, X Ma, RJ Rebello, H Chan, ...
Molecular & Cellular Proteomics 18 (7), 1410-1427, 2019
512019
Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity
I Takizawa, MG Lawrence, P Balanathan, R Rebello, HB Pearson, E Garg, ...
Oncotarget 6 (2), 604, 2015
512015
Estrogen receptor β activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations
S Hussain, MG Lawrence, RA Taylor, CYW Lo, APC BioResource, ...
PloS one 7 (7), e40732, 2012
422012
Epithelial-mesenchymal transition in prostate cancer and the potential role of kallikrein serine proteases
MG Lawrence, TL Veveris-Lowe, AK Whitbread, DL Nicol, JA Clements
Cells Tissues Organs 185 (1-3), 111-115, 2007
422007
A variant of the KLK4 gene is expressed as a cis sense–antisense chimeric transcript in prostate cancer cells
J Lai, ML Lehman, ME Dinger, SC Hendy, TR Mercer, I Seim, ...
Rna 16 (6), 1156-1166, 2010
402010
Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate‐tolerant cells
LH Porter, K Hashimoto, MG Lawrence, C Pezaro, D Clouston, H Wang, ...
BJU international 121 (6), 971-978, 2018
392018
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