Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease M Shi, C Liu, TJ Cook, KM Bullock, Y Zhao, C Ginghina, Y Li, P Aro, ... Acta neuropathologica 128, 639-650, 2014 | 615 | 2014 |
PBDEs altered gut microbiome and bile acid homeostasis in male C57BL/6 mice CY Li, JL Dempsey, D Wang, SW Lee, KM Weigel, Q Fei, DK Bhatt, ... Drug Metabolism and Disposition 46 (8), 1226-1240, 2018 | 68 | 2018 |
Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney CY Li, A Basit, A Gupta, Z Gáborik, E Kis, B Prasad The Journal of steroid biochemistry and molecular biology 191, 105350, 2019 | 50 | 2019 |
Novel interactions between gut microbiome and host drug-processing genes modify the hepatic metabolism of the environmental chemicals polybrominated diphenyl ethers CY Li, S Lee, S Cade, LJ Kuo, IR Schultz, DK Bhatt, B Prasad, ... Drug Metabolism and Disposition 45 (11), 1197-1214, 2017 | 44 | 2017 |
Age-specific regulation of drug-processing genes in mouse liver by ligands of xenobiotic-sensing transcription factors CY Li, HJ Renaud, CD Klaassen, JY Cui Drug Metabolism and Disposition 44 (7), 1038-1049, 2016 | 38 | 2016 |
Regulation of drug transport proteins—From mechanisms to clinical impact: A white paper on behalf of the international transporter consortium KLR Brouwer, R Evers, E Hayden, S Hu, CY Li, ... Clinical Pharmacology & Therapeutics 112 (3), 461-484, 2022 | 37 | 2022 |
Optimized renal transporter quantification by using aquaporin 1 and aquaporin 2 as anatomical markers: application in characterizing the ontogeny of renal transporters and its … CY Li, C Hosey-Cojocari, A Basit, JD Unadkat, JS Leeder, B Prasad The AAPS journal 21, 1-8, 2019 | 37 | 2019 |
Polybrominated diphenyl ethers and gut microbiome modulate metabolic syndrome–related aqueous metabolites in mice DK Scoville, CY Li, D Wang, JL Dempsey, D Raftery, S Mani, H Gu, JY Cui Drug Metabolism and Disposition 47 (8), 928-940, 2019 | 37 | 2019 |
Flexible catalytic site conformations implicated in modulation of HIV-1 protease autoprocessing reactions L Huang, Y Li, C Chen Retrovirology 8, 1-12, 2011 | 29 | 2011 |
Regulation of protein-coding gene and long noncoding RNA pairs in liver of conventional and germ-free mice following oral PBDE exposure CY Li, JY Cui PLoS One 13 (8), e0201387, 2018 | 25 | 2018 |
Editor’s highlight: neonatal activation of the xenobiotic-sensors PXR and CAR results in acute and persistent down-regulation of PPARα-signaling in mouse liver CY Li, SL Cheng, TK Bammler, JY Cui Toxicological Sciences 153 (2), 282-302, 2016 | 24* | 2016 |
Contribution of uptake and efflux transporters to oral pharmacokinetics of furosemide R Chapa, CY Li, A Basit, A Thakur, MK Ladumor, S Sharma, S Singh, ... ACS omega 5 (51), 32939-32950, 2020 | 20 | 2020 |
OATP-mediated hepatic uptake of glucuronide metabolites of androgens CY Li, A Gupta, Z Gáborik, E Kis, B Prasad Molecular Pharmacology 98 (3), 234-242, 2020 | 14 | 2020 |
Transcriptomic profiling of PBDE-exposed HepaRG cells unveils critical lncRNA-PCG pairs involved in intermediary metabolism A Zhang, CY Li, EJ Kelly, L Sheppard, JY Cui PLoS One 15 (2), e0224644, 2020 | 11 | 2020 |
Regulation of Xenobiotic metabolism in the liver JY Cui, CY Li Comprehensive Toxicology (Third Edition) 2, 168-214, 2018 | 8 | 2018 |
Pitfalls in Predicting Hepatobiliary Drug Transport Using Human Sandwich-Cultured Hepatocytes V Kumar, CY Li, K Ishida, E Kis, Z Gáborik, JD Unadkat The AAPS J 22 (5), 110, 2020 | 7 | 2020 |
Relevance of human aldoketoreductases and microbial β-glucuronidases in testosterone disposition A Basit, JK Amory, VS Mettu, CY Li, S Heyward, PB Jariwala, MR Redinbo, ... Drug Metabolism and Disposition 51 (4), 427-435, 2023 | 4 | 2023 |
Prediction of hepatobiliary clearances and hepatic concentrations of transported drugs in humans using rosuvastatin as a model drug F Storelli, CY Li, M Sachar, V Kumar, S Heyward, Z Sáfár, E Kis, ... Clinical Pharmacology & Therapeutics 112 (3), 593-604, 2022 | 4 | 2022 |
Epigenetics in Toxicology JY Cui, CY Li Comprehensive Toxicology (Third Edition) 1, 415-446, 2018 | 2 | 2018 |
Novel mechanisms of testosterone detoxification in UGT2B17 gene deletion carriers and androgen activation by gut microbiome A Basit, J Amory, C Li, V Mettu, S Heyward, P Jariwala, M Redinbo, ... The FASEB Journal 35, 2021 | 1 | 2021 |