| Artemisinins target the SERCA of Plasmodium falciparum U Eckstein-Ludwig, RJ Webb, IDA Van Goethem, JM East, AG Lee, ... Nature 424 (6951), 957-961, 2003 | 1349 | 2003 |
| 4-Aminoquinolines—Past, present, and future; A chemical perspective PM O'Neill, PG Bray, SR Hawley, SA Ward, BK Park Pharmacology & therapeutics 77 (1), 29-58, 1998 | 393 | 1998 |
| Access to hematin: the basis of chloroquine resistance PG Bray, M Mungthin, RG Ridley, SA Ward Molecular pharmacology 54 (1), 170-179, 1998 | 331 | 1998 |
| Pentamidine uptake and resistance in pathogenic protozoa: past, present and future PG Bray, MP Barrett, SA Ward, HP de Koning Trends in parasitology 19 (5), 232-239, 2003 | 325 | 2003 |
| A critical role for PfCRT K76T in Plasmodium falciparum verapamil‐reversible chloroquine resistance V Lakshmanan, PG Bray, D Verdier‐Pinard, DJ Johnson, P Horrocks, ... The EMBO journal 24 (13), 2294-2305, 2005 | 297 | 2005 |
| Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance PG Bray, RE Martin, L Tilley, SA Ward, K Kirk, DA Fidock Molecular microbiology 56 (2), 323-333, 2005 | 291 | 2005 |
| Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents DJ Johnson, DA Fidock, M Mungthin, V Lakshmanan, ABS Sidhu, ... Molecular cell 15 (6), 867-877, 2004 | 245 | 2004 |
| Relationship between Antimalarial Drug Activity, Accumulation, and Inhibition of Heme Polymerization in Plasmodium falciparum In Vitro SR Hawley, PG Bray, M Mungthin, JD Atkinson, PM O’Neill, SA Ward Antimicrobial agents and chemotherapy 42 (3), 682-686, 1998 | 233 | 1998 |
| Cellular Uptake of Chloroquine Is Dependent on Binding to Ferriprotoporphyrin IX and Is Independent of NHE Activity in Plasmodium falciparum PG Bray, O Janneh, KJ Raynes, M Mungthin, H Ginsburg, SA Ward The Journal of cell biology 145 (2), 363-376, 1999 | 219 | 1999 |
| Plant homologs of the Plasmodium falciparum chloroquine-resistance transporter, PfCRT, are required for glutathione homeostasis and stress responses SC Maughan, M Pasternak, N Cairns, G Kiddle, T Brach, R Jarvis, F Haas, ... Proceedings of the National Academy of Sciences 107 (5), 2331-2336, 2010 | 207 | 2010 |
| Quinolines and artemisinin: chemistry, biology and history PG Bray, SA Ward, PM O’neill Malaria: drugs, disease and post-genomic biology, 3-38, 2005 | 205 | 2005 |
| Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials PM O'Neill, A Mukhtar, PA Stocks, LE Randle, S Hindley, SA Ward, ... Journal of medicinal chemistry 46 (23), 4933-4945, 2003 | 184 | 2003 |
| Novel Short Chain Chloroquine Analogues Retain Activity Against Chloroquine Resistant K1 Plasmodium falciparum PA Stocks, KJ Raynes, PG Bray, BK Park, PM O'Neill, SA Ward Journal of Medicinal Chemistry 45 (23), 4975-4983, 2002 | 171 | 2002 |
| P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance? K Jones, PG Bray, SH Khoo, RA Davey, ER Meaden, SA Ward, DJ Back Aids 15 (11), 1353-1358, 2001 | 171 | 2001 |
| Identification of a 1, 2, 4, 5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins PM O'Neill, RK Amewu, GL Nixon, F BousejraElGarah, M Mungthin, ... Angewandte Chemie-International Edition 49 (33), 5693, 2010 | 169 | 2010 |
| Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs PA Stocks, PG Bray, VE Barton, M Al-Helal, M Jones, NC Araujo, ... Angewandte Chemie-International Edition 46 (33), 6278-6283, 2007 | 168 | 2007 |
| Functional Characterization and Target Validation of Alternative Complex I of Plasmodium falciparum Mitochondria GA Biagini, P Viriyavejakul, PM O'neill, PG Bray, SA Ward Antimicrobial agents and chemotherapy 50 (5), 1841-1851, 2006 | 168 | 2006 |
| Risk of multiple sclerosis exacerbation during pregnancy and breast-feeding LM Nelson, GM Franklin, MC Jones, G Belendiuk, B Kasper, D Klatzman, ... Jama 259 (23), 3441-3443, 1988 | 166 | 1988 |
| Acidification of the malaria parasite's digestive vacuole by a H+-ATPase and a H+-pyrophosphatase KJ Saliba, RJW Allen, S Zissis, PG Bray, SA Ward, K Kirk Journal of Biological Chemistry 278 (8), 5605-5612, 2003 | 164 | 2003 |
| Central role of hemoglobin degradation in mechanisms of action of 4-aminoquinolines, quinoline methanols, and phenanthrene methanols M Mungthin, PG Bray, RG Ridley, SA Ward Antimicrobial agents and chemotherapy 42 (11), 2973-2977, 1998 | 155 | 1998 |
