Katarzyna (Kathy) Jastrzebski
Katarzyna (Kathy) Jastrzebski
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CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes
B Evers, K Jastrzebski, JPM Heijmans, W Grernrum, RL Beijersbergen, ...
Nature biotechnology 34 (6), 631-633, 2016
Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function
K Jastrzebski, KM Hannan, EB Tchoubrieva, RD Hannan, RB Pearson
Growth factors 25 (4), 209-226, 2007
AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer
JC Chan, KM Hannan, K Riddell, PY Ng, A Peck, RS Lee, S Hung, ...
Science signaling 4 (188), ra56-ra56, 2011
Optimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens
Ž Strezoska, A Licon, J Haimes, KJ Spayd, KM Patel, K Sullivan, ...
Public Library of Science 7 (8), e42341, 2012
Sensitizing Triple-Negative Breast Cancer to PI3K Inhibition by Cotargeting IGF1RSensitizing TNBC to PI3K Inhibition by Cotargeting IGF1R
K de Lint, JB Poell, H Soueidan, K Jastrzebski, J Vidal Rodriguez, ...
Molecular cancer therapeutics 15 (7), 1545-1556, 2016
PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity
O Gilan, J Diesch, M Amalia, K Jastrzebski, AC Chueh, NM Verrills, ...
Oncogene 34 (10), 1333-1339, 2015
S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila
NC Mitchell, EB Tchoubrieva, A Chahal, S Woods, A Lee, JI Lin, ...
Cellular signalling 27 (10), 2045-2053, 2015
A phospho-proteomic screen identifies novel S6K1 and mTORC1 substrates revealing additional complexity in the signaling network regulating cell growth
K Jastrzebski, KM Hannan, CM House, SSC Hung, RB Pearson, ...
Cellular signalling 23 (8), 1338-1347, 2011
Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell LinesIntegrative Modeling of Inhibitor Sensitivity
K Jastrzebski, B Thijssen, RJC Kluin, K De Lint, IJ Majewski, ...
Cancer research 78 (15), 4396-4410, 2018
Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription
SS Hung, A Lesmana, A Peck, R Lee, E Tchoubrieva, KM Hannan, J Lin, ...
Gene 612, 36-48, 2017
Pooled shRNA screening in mammalian cells as a functional genomic discovery platform
K Jastrzebski, B Evers, RL Beijersbergen
High-Throughput RNAi Screening, 49-73, 2016
Delineating feedback activity in the mapk and akt pathways using feedback-enabled inference of signaling activity
B Thijssen, K Jastrzebski, RL Beijersbergen, LFA Wessels
bioRxiv, 268359, 2018
Optimized Cas9 expression improves performance of large-scale CRISPR screening
JMF Neto, K Jastrzebski, C Lieftink, L Krenning, M Dias, B Morris, ...
bioRxiv, 2021
Optimized Cas9 expression improves performance of large-scale CRISPR screening
FN JM, K Jastrzebski, C Lieftink, L Krenning, M Dias, B Morris, ...
PO-467 Integrative modelling to understand and predict cancer drug response
K Jastrzebski, B Thijssen, I Majewski, L Mulder, M Van Ramshorst, E Lips, ...
ESMO Open 3, A205, 2018
Role of S6K Signaling in the Regulation of in the Regulation of RRNA Gene Transcription, Ribosome Biogenesis and Cellular Growth
K Jastrzebski
University of Melbourne, Department of Biochemistry and Molecular Biology, 2007
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