| CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes B Evers, K Jastrzebski, JPM Heijmans, W Grernrum, RL Beijersbergen, ... Nature biotechnology 34 (6), 631-633, 2016 | 347 | 2016 |
| Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function K Jastrzebski, KM Hannan, EB Tchoubrieva, RD Hannan, RB Pearson Growth factors 25 (4), 209-226, 2007 | 294 | 2007 |
| AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer JC Chan, KM Hannan, K Riddell, PY Ng, A Peck, RS Lee, S Hung, ... Science signaling 4 (188), ra56-ra56, 2011 | 150 | 2011 |
| Optimized PCR conditions and increased shRNA fold representation improve reproducibility of pooled shRNA screens Ž Strezoska, A Licon, J Haimes, KJ Spayd, KM Patel, K Sullivan, ... Public Library of Science 7 (8), e42341, 2012 | 41 | 2012 |
| Sensitizing Triple-Negative Breast Cancer to PI3K Inhibition by Cotargeting IGF1RSensitizing TNBC to PI3K Inhibition by Cotargeting IGF1R K de Lint, JB Poell, H Soueidan, K Jastrzebski, J Vidal Rodriguez, ... Molecular cancer therapeutics 15 (7), 1545-1556, 2016 | 28 | 2016 |
| PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity O Gilan, J Diesch, M Amalia, K Jastrzebski, AC Chueh, NM Verrills, ... Oncogene 34 (10), 1333-1339, 2015 | 24 | 2015 |
| S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila NC Mitchell, EB Tchoubrieva, A Chahal, S Woods, A Lee, JI Lin, ... Cellular signalling 27 (10), 2045-2053, 2015 | 23 | 2015 |
| A phospho-proteomic screen identifies novel S6K1 and mTORC1 substrates revealing additional complexity in the signaling network regulating cell growth K Jastrzebski, KM Hannan, CM House, SSC Hung, RB Pearson, ... Cellular signalling 23 (8), 1338-1347, 2011 | 22 | 2011 |
| Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell LinesIntegrative Modeling of Inhibitor Sensitivity K Jastrzebski, B Thijssen, RJC Kluin, K De Lint, IJ Majewski, ... Cancer research 78 (15), 4396-4410, 2018 | 19 | 2018 |
| Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription SS Hung, A Lesmana, A Peck, R Lee, E Tchoubrieva, KM Hannan, J Lin, ... Gene 612, 36-48, 2017 | 16 | 2017 |
| Pooled shRNA screening in mammalian cells as a functional genomic discovery platform K Jastrzebski, B Evers, RL Beijersbergen High-Throughput RNAi Screening, 49-73, 2016 | 6 | 2016 |
| Delineating feedback activity in the mapk and akt pathways using feedback-enabled inference of signaling activity B Thijssen, K Jastrzebski, RL Beijersbergen, LFA Wessels bioRxiv, 268359, 2018 | 3 | 2018 |
| Optimized Cas9 expression improves performance of large-scale CRISPR screening JMF Neto, K Jastrzebski, C Lieftink, L Krenning, M Dias, B Morris, ... bioRxiv, 2021 | 1 | 2021 |
| Optimized Cas9 expression improves performance of large-scale CRISPR screening FN JM, K Jastrzebski, C Lieftink, L Krenning, M Dias, B Morris, ... | | 2021 |
| PO-467 Integrative modelling to understand and predict cancer drug response K Jastrzebski, B Thijssen, I Majewski, L Mulder, M Van Ramshorst, E Lips, ... ESMO Open 3, A205, 2018 | | 2018 |
| Role of S6K Signaling in the Regulation of in the Regulation of RRNA Gene Transcription, Ribosome Biogenesis and Cellular Growth K Jastrzebski University of Melbourne, Department of Biochemistry and Molecular Biology, 2007 | | 2007 |
Ross HannanProfessor Ross Hannan, Centenary Chair of Cancer Research, Associate Dean of ResearchVerified email at anu.edu.au
