An overview of the serpin superfamily RHP Law, Q Zhang, S McGowan, AM Buckle, GA Silverman, W Wong, ... Genome biology 7, 1-11, 2006 | 907 | 2006 |
The anticoagulant activation of antithrombin by heparin L Jin, JP Abrahams, R Skinner, M Petitou, RN Pike, RW Carrell Proceedings of the National Academy of Sciences 94 (26), 14683-14688, 1997 | 903 | 1997 |
Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function JA Irving, RN Pike, AM Lesk, JC Whisstock Genome research 10 (12), 1845-1864, 2000 | 780 | 2000 |
A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis SW Scally, J Petersen, SC Law, NL Dudek, HJ Nel, KL Loh, ... Journal of Experimental Medicine 210 (12), 2569-2582, 2013 | 485 | 2013 |
Lysine-and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins. R Pike, W McGraw, J Potempa, J Travis Journal of Biological Chemistry 269 (1), 406-411, 1994 | 425 | 1994 |
Corruption of innate immunity by bacterial proteases J Potempa, RN Pike Journal of innate immunity 1 (2), 70-87, 2009 | 346 | 2009 |
PROSPER: an integrated feature-based tool for predicting protease substrate cleavage sites J Song, H Tan, AJ Perry, T Akutsu, GI Webb, JC Whisstock, RN Pike PloS one 7 (11), e50300, 2012 | 338 | 2012 |
The multiple forms of trypsin-like activity present in various strains of Porphyromonas gingivalis are due to the presence of either Arg-gingipain or Lys-gingipain J Potempa, R Pike, J Travis Infection and immunity 63 (4), 1176-1182, 1995 | 334 | 1995 |
A common fold mediates vertebrate defense and bacterial attack CJ Rosado, AM Buckle, RHP Law, RE Butcher, WT Kan, CH Bird, K Ung, ... Science 317 (5844), 1548-1551, 2007 | 329 | 2007 |
Arginine-Specific Protease fromPorphyromonas gingivalis Activates Protease-Activated Receptors on Human Oral Epithelial Cells and Induces Interleukin-6 … A Lourbakos, J Potempa, J Travis, MR D'Andrea, P Andrade-Gordon, ... Infection and immunity 69 (8), 5121-5130, 2001 | 301 | 2001 |
Activation of protease-activated receptors by gingipains fromPorphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity A Lourbakos, YP Yuan, AL Jenkins, J Travis, P Andrade-Gordon, ... Blood, The Journal of the American Society of Hematology 97 (12), 3790-3797, 2001 | 294 | 2001 |
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop G Fenalti, RHP Law, AM Buckle, C Langendorf, K Tuck, CJ Rosado, ... Nature structural & molecular biology 14 (4), 280-286, 2007 | 267 | 2007 |
Porphyromonas gingivalis proteinases as virulence factors in the development of periodontitis J Travis, R Pike, T Imamura, J Potempa Journal of periodontal research 32 (1), 120-125, 1997 | 259 | 1997 |
The X-ray crystal structure of full-length human plasminogen RHP Law, T Caradoc-Davies, N Cowieson, AJ Horvath, AJ Quek, ... Cell reports 1 (3), 185-190, 2012 | 258 | 2012 |
Titration and Mapping of the Active Site of Cysteine Proteinases from Porphyromonas gingivalis (Gingipains) Using Peptidyl Chloromethanes J Potempa, R Pike, J Travis Walter de Gruyter, Berlin/New York 378 (3-4), 223-230, 1997 | 243 | 1997 |
Molecular Cloning and Structural Characterization of the Arg-gingipain Proteinase of Porphyromonas gingivalis: BIOSYNTHESIS AS A PROTEINASE-ADHESIN POLYPROTEIN (∗) N Pavloff, J Potempa, RN Pike, V Prochazka, MC Kiefer, J Travis, PJ Barr Journal of Biological Chemistry 270 (3), 1007-1010, 1995 | 226 | 1995 |
Antithrombin: in control of coagulation NS Quinsey, AL Greedy, SP Bottomley, JC Whisstock, RN Pike The international journal of biochemistry & cell biology 36 (3), 386-389, 2004 | 225 | 2004 |
Pathogenesis of periodontitis: a major arginine-specific cysteine proteinase from Porphyromonas gingivalis induces vascular permeability enhancement through activation of the … T Imamura, RN Pike, J Potempa, J Travis The Journal of clinical investigation 94 (1), 361-367, 1994 | 221 | 1994 |
Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis A Lourbakos, C Chinni, P Thompson, J Potempa, J Travis, EJ Mackie, ... FEBS letters 435 (1), 45-48, 1998 | 208 | 1998 |
Control of the coagulation system by serpins: getting by with a little help from glycosaminoglycans RN Pike, AM Buckle, BF le Bonniec, FC Church The FEBS journal 272 (19), 4842-4851, 2005 | 178 | 2005 |