Daniel B. Hardy, PhD
Daniel B. Hardy, PhD
Associate Professor, Depts of Physiology and Pharmacology and Ob/Gyn, University of Western Ontario
Verified email at - Homepage
Cited by
Cited by
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
BA Janowski, ST Younger, DB Hardy, R Ram, KE Huffman, DR Corey
Nature chemical biology 3 (3), 166-173, 2007
Antisense transcripts are targets for activating small RNAs
JC Schwartz, ST Younger, NB Nguyen, DB Hardy, BP Monia, DR Corey, ...
Nature structural & molecular biology 15 (8), 842-848, 2008
Up-regulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of nuclear factor-κB may contribute to the onset of labor through inhibition of …
JC Condon, DB Hardy, K Kovaric, CR Mendelson
Molecular endocrinology 20 (4), 764-775, 2006
Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-κB activation of cyclooxygenase 2 expression
DB Hardy, BA Janowski, DR Corey, CR Mendelson
Molecular endocrinology 20 (11), 2724-2733, 2006
Developmental origins of health and disease: current knowledge and potential mechanisms
DJ Hoffman, RM Reynolds, DB Hardy
Nutrition reviews 75 (12), 951-970, 2017
Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs
BA Janowski, KE Huffman, JC Schwartz, R Ram, D Hardy, DS Shames, ...
Nature chemical biology 1 (4), 216-222, 2005
Inflammatory status influences aromatase and steroid receptor expression in endometriosis
O Bukulmez, DB Hardy, BR Carr, RA Word, CR Mendelson
Endocrinology 149 (3), 1190-1204, 2008
Developmental origins of metabolic diseases
DJ Hoffman, TL Powell, ES Barrett, DB Hardy
Physiological reviews 101 (3), 739-795, 2021
Inhibiting transcription of chromosomal DNA with antigene peptide nucleic acids
BA Janowski, K Kaihatsu, KE Huffman, JC Schwartz, R Ram, D Hardy, ...
Nature chemical biology 1 (4), 210-215, 2005
Maternal protein restriction elevates cholesterol in adult rat offspring due to repressive changes in histone modifications at the cholesterol 7 α-hydroxylase promoter
G Sohi, K Marchand, A Revesz, E Arany, DB Hardy
Molecular endocrinology 25 (5), 785-798, 2011
Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.
GA Arreaza, MJ Cameron, A Jaramillo, BM Gill, D Hardy, KB Laupland, ...
The Journal of clinical investigation 100 (9), 2243-2253, 1997
Δ9-tetrahydrocannabinol exposure during rat pregnancy leads to symmetrical fetal growth restriction and labyrinth-specific vascular defects in the placenta
BV Natale, KN Gustin, K Lee, AC Holloway, SR Laviolette, DRC Natale, ...
Scientific reports 10 (1), 544, 2020
Progesterone receptor inhibits proliferation of human breast cancer cells via induction of MAPK phosphatase 1 (MKP-1/DUSP1)
CC Chen, DB Hardy, CR Mendelson
Journal of Biological Chemistry 286 (50), 43091-43102, 2011
The expression of 11β-hydroxysteroid dehydrogenase type 2 is induced during trophoblast differentiation: effects of hypoxia
DB Hardy, K Yang
The Journal of Clinical Endocrinology & Metabolism 87 (8), 3696-3701, 2002
Progesterone receptor inhibits aromatase and inflammatory response pathways in breast cancer cells via ligand-dependent and ligand-independent mechanisms
DB Hardy, BA Janowski, CC Chen, CR Mendelson
Molecular Endocrinology 22 (8), 1812-1824, 2008
Molecular mechanisms underlying the fetal programming of adult disease
T Vo, DB Hardy
Journal of cell communication and signaling 6 (3), 139-153, 2012
Retinoic acid stimulates the expression of 11β-hydroxysteroid dehydrogenase type 2 in human choriocarcinoma JEG-3 cells
J Tremblay, DB Hardy, LE Pereira, K Yang
Biology of reproduction 60 (3), 541-545, 1999
Androstenedione up-regulation of endometrial aromatase expression via local conversion to estrogen: potential relevance to the pathogenesis of endometriosis
O Bukulmez, DB Hardy, BR Carr, RJ Auchus, T Toloubeydokhti, RA Word, ...
The Journal of Clinical Endocrinology & Metabolism 93 (9), 3471-3477, 2008
Maternal protein restriction leads to enhanced hepatic gluconeogenic gene expression in adult male rat offspring due to impaired expression of the liver X receptor
TX Vo, A Revesz, G Sohi, N Ma, DB Hardy
Journal of endocrinology 218 (1), 85, 2013
Adverse effects of perinatal nicotine exposure on reproductive outcomes
MK Wong, NG Barra, N Alfaidy, DB Hardy, AC Holloway
Reproduction 150 (6), R185-R193, 2015
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