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Kurt De Vos
Kurt De Vos
Verified email at sheffield.ac.uk
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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ...
Science 323 (5918), 1208-1211, 2009
31232009
Role of axonal transport in neurodegenerative diseases
KJ De Vos, AJ Grierson, S Ackerley, CCJ Miller
Annu. Rev. Neurosci. 31 (1), 151-173, 2008
8942008
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity.
V Goossens, J Grooten, K De Vos, W Fiers
Proceedings of the National Academy of Sciences 92 (18), 8115-8119, 1995
7551995
ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43
R Stoica, KJ De Vos, S Paillusson, S Mueller, RM Sancho, KF Lau, ...
Nature communications 5 (1), 3996, 2014
6472014
The role of mitochondria in amyotrophic lateral sclerosis
EF Smith, PJ Shaw, KJ De Vos
Neuroscience letters 710, 132933, 2019
5802019
VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis
KJ De Vos, GM Morotz, R Stoica, EL Tudor, KF Lau, S Ackerley, A Warley, ...
Human molecular genetics 21 (6), 1299-1311, 2012
5602012
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ...
Human molecular genetics 16 (22), 2720-2728, 2007
5062007
The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy
CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ...
The EMBO journal 35 (15), 1656-1676, 2016
4862016
Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission
KJ De Vos, VJ Allan, AJ Grierson, MP Sheetz
Current Biology 15 (7), 678-683, 2005
4042005
Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity
K Vancompernolle, F Van Herreweghe, G Pynaert, M Van de Craen, ...
FEBS letters 438 (3), 150-158, 1998
3941998
Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations
VK Godena, N Brookes-Hocking, A Moller, G Shaw, M Oswald, ...
Nature communications 5 (1), 5245, 2014
3032014
ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP 51 interaction and ER–mitochondria associations
R Stoica, S Paillusson, P Gomez‐Suaga, JC Mitchell, DHW Lau, EH Gray, ...
EMBO reports 17 (9), 1326-1342, 2016
2752016
RPTP-α acts as a transducer of mechanical force on αv3-integrin–cytoskeleton linkages
G Von Wichert, G Jiang, A Kostic, K De Vos, J Sap, MP Sheetz
The Journal of cell biology 161 (1), 143-153, 2003
2692003
Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?
KJ De Vos, M Hafezparast
Neurobiology of disease 105, 283-299, 2017
2682017
The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region
K De Vos, V Goossens, E Boone, D Vercammen, K Vancompernolle, ...
Journal of Biological Chemistry 273 (16), 9673-9680, 1998
2041998
C9orf72 expansion disrupts ATM-mediated chromosomal break repair
C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ...
Nature neuroscience 20 (9), 1225-1235, 2017
1982017
Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration
TM Woodruff, JW Crane, LM Proctor, KM Buller, AB Shek, K De Vos, ...
The FASEB Journal 20 (9), 1407-1417, 2006
1712006
Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria
GM Morotz, KJ De Vos, A Vagnoni, S Ackerley, CE Shaw, CCJ Miller
Human molecular genetics 21 (9), 1979-1988, 2012
1692012
Direct evidence for axonal transport defects in a novel mouse model of mutant spastin‐induced hereditary spastic paraplegia (HSP) and human HSP patients
PR Kasher, KJ De Vos, SB Wharton, C Manser, EJ Bennett, M Bingley, ...
Journal of neurochemistry 110 (1), 34-44, 2009
1542009
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits
GM Hautbergue, LM Castelli, L Ferraiuolo, A Sanchez-Martinez, ...
Nature communications 8 (1), 16063, 2017
1522017
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