Diindolylmethane, a naturally occurring compound, induces CYP3A4 and MDR1 gene expression by activating human PXR SR Pondugula, PC Flannery, KL Abbott, ES Coleman, S Mani, T Samuel, ... Toxicology letters 232 (3), 580-589, 2015 | 50 | 2015 |
IND-2, a pyrimido [1 ″, 2 ″: 1, 5] pyrazolo [3, 4-b] quinoline derivative, circumvents multi-drug resistance and causes apoptosis in colon cancer cells C Karthikeyan, C Lee, J Moore, R Mittal, EA Suswam, KL Abbott, ... Bioorganic & medicinal chemistry 23 (3), 602-611, 2015 | 44 | 2015 |
Pyrimido [1 ″, 2 ″: 1, 5] pyrazolo [3, 4-b] quinolines: Novel compounds that reverse ABCG2-mediated resistance in cancer cells C Karthikeyan, R Malla, CR Ashby Jr, H Amawi, KL Abbott, J Moore, ... Cancer letters 376 (1), 118-126, 2016 | 33 | 2016 |
Adverse pharmacokinetic interactions between illicit substances and clinical drugs KL Abbott, PC Flannery, KS Gill, DM Boothe, M Dhanasekaran, S Mani, ... Drug Metabolism Reviews 52 (1), 44-65, 2020 | 23 | 2020 |
Oroxylum Indicum ameliorates chemotherapy induced cognitive impairment SR Pondugula, M Majrashi, M Almaghrabi, S Ramesh, KL Abbott, ... Plos one 16 (6), e0252522, 2021 | 18 | 2021 |
Stearidonic acid, a plant-based dietary fatty acid, enhances the chemosensitivity of canine lymphoid tumor cells SR Pondugula, G Ferniany, F Ashraf, KL Abbott, BF Smith, ES Coleman, ... Biochemical and Biophysical Research Communications 460 (4), 1002-1007, 2015 | 17 | 2015 |
Mg2+/Mn2+-Dependent Phosphatase 1A Is Involved in Regulating Pregnane X Receptor–Mediated Cytochrome p450 3A4 Gene Expression SR Pondugula, PC Flannery, U Apte, JR Babu, T Geetha, SD Rege, ... Drug Metabolism and Disposition 43 (3), 385-391, 2015 | 17 | 2015 |
Belinostat, at its clinically relevant concentrations, inhibits rifampicin-induced CYP3A4 and MDR1 gene expression KL Abbott, CS Chaudhury, A Chandran, S Vishveshwara, Z Dvorak, ... Molecular Pharmacology 95 (3), 324-334, 2019 | 16 | 2019 |
The combination of omega-3 stearidonic acid and docetaxel enhances cell death over docetaxel alone in human prostate cancer cells M Mansour, S van Ginkel, JC Dennis, B Mason, I Elhussin, K Abbott, ... Journal of Cancer 9 (23), 4536, 2018 | 16 | 2018 |
Cardioprotective Effects of Oroxylum indicum Extract Against Doxorubicin and Cyclophosphamide-Induced Cardiotoxicity SR Pondugula, A Harshan, S Ramesh, M Govindarajulu, M Almaghrabi, ... Cardiovascular Toxicology, 1-11, 2022 | 15 | 2022 |
Correlation of PPM1A downregulation with CYP3A4 repression in the tumor liver tissue of hepatocellular carcinoma patients PC Flannery, KL Abbott, SR Pondugula European journal of drug metabolism and pharmacokinetics 45, 297-304, 2020 | 12 | 2020 |
A clinically relevant combination treatment with doxorubicin and cyclophosphamide does not induce hepatotoxicity in C57BL/6J mice SR Pondugula, JM Salamat, KL Abbott, PC Flannery, M Majrashi, ... Liver research 5 (4), 239-242, 2021 | 5 | 2021 |
Nothing ventured, nothing gained: regulations cripple potentially life-saving research of illicit substances KL Abbott, KS Gill, PC Flannery, DM Boothe, M Dhanasekaran, ... ACS Chemical Neuroscience 11 (10), 1382-1384, 2020 | 5 | 2020 |
Interplay between the Cannabinoid system and microRNAs in cancer JM Salamat, KL Abbott, PC Flannery, EL Ledbetter, SR Pondugula ACS omega 7 (12), 9995-10000, 2022 | 4 | 2022 |
Screening for CYP3A4 inhibition and induction coupled to parallel artificial membrane permeability assay (PAMPA) for prediction of botanical-drug interactions: The case of açaí … Y Zhang, TA Rants'o, D Jung, E Lopez, K Abbott, SR Pondugula, ... Phytomedicine 59, 152915, 2019 | 4 | 2019 |
Effects of developmental exposures to Bisphenol-A and Bisphenol-S on hepatocellular function in male Long-Evans rats K Liu, S Kadannagari, J Deruiter, S Pathak, KL Abbott, JM Salamat, ... Life Sciences 326, 121752, 2023 | 3 | 2023 |
Predictable hematological markers associated with cognitive decline in valid rodent models of cognitive impairment SR Pondugula, M Majrashi, M Almaghrabi, K Abbott, M Govindarajulu, ... Toxicology Mechanisms and Methods 30 (6), 454-461, 2020 | 3 | 2020 |
Cannabinoids in cancer: Cross-talk between cannabinoids and miRNAs JM Salamat, EL Ledbetter, KL Abbott, K Thungrat, PC Flannery, ... Cannabis/marijuana for healthcare, 53-75, 2022 | 2 | 2022 |
Dysregulation of Endobiotic Homeostasis Mechanisms: Novel Insights into Adverse Pharmacokinetic Interactions between Illicit Substances and Clinical Drugs JM Salamat, KL Abbott, PC Flannery, SR Pondugula ACS Chemical Neuroscience 11 (24), 4021-4023, 2020 | 2 | 2020 |
Oroxylum indicum extract prevents chemotherapy‐induced cognitive impairment in mice SR Pondugula, M Majrashi, M Almaghrabi, KL Abbott, M Govindarajulu, ... The FASEB Journal 34 (S1), 1-1, 2020 | 2 | 2020 |