| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10662 | 2021 |
| α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models AA Cooper, AD Gitler, A Cashikar, CM Haynes, KJ Hill, B Bhullar, K Liu, ... Science 313 (5785), 324-328, 2006 | 1681 | 2006 |
| arrow encodes an LDL-receptor-related protein essential for Wingless signalling M Wehrli, ST Dougan, K Caldwell, L O'Keefe, S Schwartz, ... Nature 407 (6803), 527-530, 2000 | 1170 | 2000 |
| The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis AD Gitler, BJ Bevis, J Shorter, KE Strathearn, S Hamamichi, LJ Su, ... Proceedings of the National Academy of Sciences 105 (1), 145-150, 2008 | 639 | 2008 |
| α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity AD Gitler, A Chesi, ML Geddie, KE Strathearn, S Hamamichi, KJ Hill, ... Nature genetics 41 (3), 308-315, 2009 | 630 | 2009 |
| Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer’s disease risk factors in yeast S Treusch, S Hamamichi, JL Goodman, KES Matlack, CY Chung, V Baru, ... Science 334 (6060), 1241-1245, 2011 | 438 | 2011 |
| Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model S Hamamichi, RN Rivas, AL Knight, S Cao, KA Caldwell, GA Caldwell Proceedings of the National Academy of Sciences 105 (2), 728-733, 2008 | 353 | 2008 |
| Lysosomal impairment in Parkinson's disease B Dehay, M Martinez‐Vicente, GA Caldwell, KA Caldwell, Z Yue, ... Movement Disorders 28 (6), 725-732, 2013 | 351 | 2013 |
| Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans S Cao, CC Gelwix, KA Caldwell, GA Caldwell Journal of Neuroscience 25 (15), 3801-3812, 2005 | 324 | 2005 |
| Yeast reveal a “druggable” Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons DF Tardiff, NT Jui, V Khurana, MA Tambe, ML Thompson, CY Chung, ... Science 342 (6161), 979-983, 2013 | 291 | 2013 |
| Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho-and caspase-3-cleaved tau species CA Dickey, M Yue, WL Lin, DW Dickson, JH Dunmore, WC Lee, C Zehr, ... Journal of Neuroscience 26 (26), 6985-6996, 2006 | 286 | 2006 |
| Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity L Qiao, S Hamamichi, KA Caldwell, GA Caldwell, TA Yacoubian, S Wilson, ... Molecular brain 1, 1-18, 2008 | 268 | 2008 |
| Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events ME Jackrel, ME DeSantis, BA Martinez, LM Castellano, RM Stewart, ... Cell 156 (1), 170-182, 2014 | 241 | 2014 |
| Using Caenorhabditis elegans to probe toxicity of 1-alkyl-3-methylimidazolium chloride based ionic liquids RP Swatloski, JD Holbrey, SB Memon, GA Caldwell, KA Caldwell, ... Chemical communications, 668-669, 2004 | 241 | 2004 |
| Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration DE Mor, E Tsika, JR Mazzulli, NS Gould, H Kim, MJ Daniels, S Doshi, ... Nature neuroscience 20 (11), 1560-1568, 2017 | 220 | 2017 |
| Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models LJ Su, PK Auluck, TF Outeiro, E Yeger-Lotem, JA Kritzer, DF Tardiff, ... Disease models & mechanisms 3 (3-4), 194-208, 2010 | 219 | 2010 |
| Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity KES Matlack, DF Tardiff, P Narayan, S Hamamichi, KA Caldwell, ... Proceedings of the National Academy of Sciences 111 (11), 4013-4018, 2014 | 175 | 2014 |
| C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease AJ Harrington, S Hamamichi, GA Caldwell, KA Caldwell Developmental dynamics: an official publication of the American Association …, 2010 | 175 | 2010 |
| Rapid selection of cyclic peptides that reduce α-synuclein toxicity in yeast and animal models JA Kritzer, S Hamamichi, JM McCaffery, S Santagata, TA Naumann, ... Nature chemical biology 5 (9), 655-663, 2009 | 170 | 2009 |
| Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins GA Caldwell, S Cao, EG Sexton, CC Gelwix, JP Bevel, KA Caldwell Human molecular genetics 12 (3), 307-319, 2003 | 168 | 2003 |
Guy A CaldwellThe University of AlabamaVerified email at ua.edu
