David De Souza
David De Souza
Facility Manager, Metabolomics Australia, Bio21 Institute,The University of Melbourne
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Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130
SE Nicholson, D De Souza, LJ Fabri, J Corbin, TA Willson, JG Zhang, ...
Proceedings of the National Academy of Sciences 97 (12), 6493-6498, 2000
Microbiota-derived short-chain fatty acids promote the memory potential of antigen-activated CD8+ T cells
A Bachem, C Makhlouf, KJ Binger, DP de Souza, D Tull, K Hochheiser, ...
Immunity 51 (2), 285-297. e5, 2019
Living in a phagolysosome; metabolism of Leishmania amastigotes
MJ McConville, D De Souza, E Saunders, VA Likic, T Naderer
Trends in parasitology 23 (8), 368-375, 2007
Normalizing and integrating metabolomics data
AM De Livera, DA Dias, D De Souza, T Rupasinghe, J Pyke, D Tull, ...
Analytical chemistry 84 (24), 10768-10776, 2012
The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability
JJ Babon, EJ McManus, S Yao, DP DeSouza, LA Mielke, NS Sprigg, ...
Molecular cell 22 (2), 205-216, 2006
Virulence of Leishmania major in macrophages and mice requires the gluconeogenic enzyme fructose-1, 6-bisphosphatase
T Naderer, MA Ellis, MF Sernee, DP De Souza, J Curtis, E Handman, ...
Proceedings of the National Academy of Sciences 103 (14), 5502-5507, 2006
Synergy between the KEAP1/NRF2 and PI3K pathways drives non-small-cell lung cancer with an altered immune microenvironment
SA Best, DP De Souza, A Kersbergen, AN Policheni, S Dayalan, D Tull, ...
Cell metabolism 27 (4), 935-943. e4, 2018
Oocyst wall formation and composition in coccidian parasites
K Mai, PA Sharman, RA Walker, M Katrib, DD Souza, MJ McConville, ...
Memorias do Instituto Oswaldo Cruz 104, 281-289, 2009
SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation
DL Krebs, RT Uren, D Metcalf, S Rakar, JG Zhang, R Starr, DP De Souza, ...
Molecular and cellular biology, 2002
SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities
D De Souza, LJ Fabri, A Nash, DJ Hilton, NA Nicola, M Baca
Biochemistry 41 (29), 9229-9236, 2002
Direct production of proteins with N-terminal cysteine for site-specific conjugation
IE Gentle, DP De Souza, M Baca
Bioconjugate chemistry 15 (3), 658-663, 2004
Specific plasma lipid classes and phospholipid fatty acids indicative of dairy food consumption associate with insulin sensitivity
PJ Nestel, N Straznicky, NA Mellett, G Wong, DP De Souza, DL Tull, ...
The American journal of clinical nutrition 99 (1), 46-53, 2014
Sengers syndrome-associated mitochondrial acylglycerol kinase is a subunit of the human TIM22 protein import complex
Y Kang, DA Stroud, MJ Baker, DP De Souza, AE Frazier, M Liem, D Tull, ...
Molecular cell 67 (3), 457-470. e5, 2017
NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease
H Tye, CH Yu, LA Simms, MR de Zoete, ML Kim, M Zakrzewski, ...
Nature communications 9 (1), 3728, 2018
A dynamic programming approach for the alignment of signal peaks in multiple gas chromatography-mass spectrometry experiments
MD Robinson, DP De Souza, WW Keen, EC Saunders, MJ McConville, ...
BMC bioinformatics 8, 1-14, 2007
PyMS: a Python toolkit for processing of gas chromatography-mass spectrometry (GC-MS) data. Application and comparative study of selected tools
S O'Callaghan, DP De Souza, A Isaac, Q Wang, L Hodkinson, ...
BMC bioinformatics 13, 1-18, 2012
LeishCyc: a biochemical pathways database for Leishmania major
MA Doyle, JI MacRae, DP De Souza, EC Saunders, MJ McConville, ...
BMC systems biology 3, 1-12, 2009
Host reticulocytes provide metabolic reservoirs that can be exploited by malaria parasites
A Srivastava, DJ Creek, KJ Evans, D De Souza, L Schofield, S Müller, ...
PLoS pathogens 11 (6), e1004882, 2015
Progressive peak clustering in GC-MS Metabolomic experiments applied to Leishmania parasites
DP De Souza, EC Saunders, MJ McConville, VA Likić
Bioinformatics 22 (11), 1391-1396, 2006
Profiling of polar metabolites in biological extracts using diamond hydride‐based aqueous normal phase chromatography
DL Callahan, DD Souza, A Bacic, U Roessner
Journal of separation science 32 (13), 2273-2280, 2009
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