| Efficient affinity maturation of antibody variable domains requires co-selection of compensatory mutations to maintain thermodynamic stability MC Julian, L Li, S Garde, R Wilen, PM Tessier Scientific Reports 7, 45259, 2017 | 100 | 2017 |
| Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs KE Tiller, L Li, S Kumar, MC Julian, S Garde, PM Tessier Journal of Biological Chemistry 292 (40), 16638-16652, 2017 | 66 | 2017 |
| Net charge of antibody complementarity-determining regions is a key predictor of specificity LA Rabia, Y Zhang, SD Ludwig, MC Julian, PM Tessier Protein Engineering, Design and Selection 31 (11), 409-418, 2018 | 63 | 2018 |
| Design and optimization of anti-amyloid domain antibodies specific for β-amyloid and islet amyloid polypeptide CC Lee, MC Julian, KE Tiller, F Meng, SE DuConge, R Akter, DP Raleigh, ... Journal of Biological Chemistry 291 (6), 2858-2873, 2016 | 49 | 2016 |
| Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies MC Julian, CC Lee, KE Tiller, LA Rabia, EK Day, AJ Schick III, PM Tessier Protein Engineering, Design and Selection 28 (10), 339-350, 2015 | 40 | 2015 |
| Nature-inspired design and evolution of anti-amyloid antibodies MC Julian, LA Rabia, AA Desai, A Arsiwala, JE Gerson, HL Paulson, ... Journal of Biological Chemistry 294 (21), 8438-8451, 2019 | 27 | 2019 |
| Systematic engineering of optimized autonomous heavy-chain variable domains J Nilvebrant, J Ereño-Orbea, M Gorelik, MC Julian, PM Tessier, JP Julien, ... Journal of Molecular Biology 433 (21), 167241, 2021 | 4 | 2021 |
| Directed evolution and optimization of antibodies for enhanced affinity and stability MC Julian Rensselaer Polytechnic Institute, 2017 | | 2017 |
Peter TessierUniversity of MichiganVerified email at umich.edu
