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Mike Clark
Mike Clark
Retired (30th Sept 2014) as Reader in Therapeutic and Molecular Immunology, Cambridge University
Verified email at cam.ac.uk - Homepage
Title
Cited by
Cited by
Year
Reshaping human antibodies for therapy
L Riechmann, M Clark, H Waldmann, G Winter
Nature 332 (6162), 323-327, 1988
35941988
Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.
M Brüggemann, GT Williams, CI Bindon, MR Clark, MR Walker, R Jefferis, ...
The Journal of experimental medicine 166 (5), 1351, 1987
10911987
Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H
G Hale, MR Clark, R Marcus, G Winter, MJS Dyer, JM Phillips, ...
The Lancet 332 (8625), 1394-1399, 1988
7321988
Recombinant human IgG molecules lacking Fc receptor I binding and monocyte triggering activities
KL Armour, MR Clark, AG Hadley, LM Williamson
European journal of immunology 29, 2613-2624, 1999
5251999
Antibody humanization: a case of the "Emperor's new clothes"?
M Clark
Immunology today 21 (8), 397-402, 2000
4672000
IgG Effector Functions
MR Clark
Chemical immunology 65, 88-110, 1997
341*1997
The generation of a humanized, non‐mitogenic CD3 monoclonal antibody which retains in vitro immunosuppressive properties
S Bolt, E Routledge, I Lloyd, L Chatenoud, H Pope, SD Gorman, M Clark, ...
European journal of immunology 23 (2), 403-411, 1993
3131993
American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006
M Clark, JF Colombel, BC Feagan, RN Fedorak, SB Hanauer, MA Kamm, ...
Gastroenterology 133 (1), 312-339, 2007
3032007
Monoclonal-antibody therapy in systemic vasculitis
PW Mathieson, SP Cobbold, G Hale, MR Clark, DBG Oliveira, ...
New England Journal of Medicine 323 (4), 250-254, 1990
3011990
Reshaping a therapeutic CD4 antibody
SD Gorman, MR Clark, EG Routledge, SP Cobbold, H Waldmann
Proceedings of the National Academy of Sciences 88 (10), 4181, 1991
2441991
Humanized anti-CD3 specific antibodies
SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldmann, ...
US Patent 6,706,265, 2004
231*2004
Tolerance to rat monoclonal antibodies. Implications for serotherapy.
RJ Benjamin, SP Cobbold, MR Clark, H Waldmann
The Journal of experimental medicine 163 (6), 1539-1552, 1986
2171986
Structural motifs involved in human IgG antibody effector functions
J Greenwood, M Clark, H Waldmann
European journal of immunology 23 (5), 1098-1104, 1993
2141993
Humanized anti-CD3 specific antibodies
SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldman
US Patent App. 11/300,396, 2005
202*2005
Humanized anti-CD3 specific antibodies
SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldmann
US Patent 5,585,097, 1996
2021996
Humanized anti-CD3 specific antibodies
SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldman
US Patent App. 11/501,894, 2006
199*2006
Humanized anti-CD3 specific antibodies
SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldman
US Patent App. 10/743,423, 2003
196*2003
Humanized anti-CD3 specific antibodies
S Bolt, M Clark, S Gorman, E Routledge, H Waldman
US Patent App. 11/300,278, 2005
195*2005
Humanized anti-CD3 specific antibodies
SL Bolt, MR Clark, SD Gorman, EG Routledge, H Waldman
US Patent App. 11/300,279, 2005
195*2005
Differential binding to human FcγRIIa and FcγRIIb receptors by human IgG wildtype and mutant antibodies
KL Armour, JGJ van de Winkel, LM Williamson, MR Clark
Molecular immunology 40 (9), 585-593, 2003
1932003
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