|Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism|
M Steinhoff, N Vergnolle, SH Young, M Tognetto, S Amadesi, HS Ennes, ...
Nature medicine 6 (2), 151-158, 2000
|NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2|
JL Wallace, W McKnight, BK Reuter, N Vergnolle
Gastroenterology 119 (3), 706-714, 2000
|Role for protease activity in visceral pain in irritable bowel syndrome|
N Cenac, CN Andrews, M Holzhausen, K Chapman, G Cottrell, ...
The Journal of clinical investigation 117 (3), 636-647, 2007
|Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response|
M Steinhoff, J Buddenkotte, V Shpacovitch, A Rattenholl, C Moormann, ...
Endocrine reviews 26 (1), 1-43, 2005
|Proteinase-activated receptor-2 and hyperalgesia: a novel pain pathway|
N Vergnolle, NW Bunnett, KA Sharkey, V Brussee, SJ Compton, EF Grady, ...
Nature medicine 7 (7), 821-826, 2001
|Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia|
S Amadesi, J Nie, N Vergnolle, GS Cottrell, EF Grady, M Trevisani, ...
Journal of Neuroscience 24 (18), 4300-4312, 2004
|Protease-activated receptors in inflammation, neuronal signaling and pain|
N Vergnolle, JL Wallace, NW Bunnett, MD Hollenberg
Trends in Pharmacological Sciences 22 (3), 146-152, 2001
|Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2|
N Cenac, AM Coelho, C Nguyen, S Compton, P Andrade-Gordon, ...
The American journal of pathology 161 (5), 1903-1915, 2002
|Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice|
AD Grant, GS Cottrell, S Amadesi, M Trevisani, P Nicoletti, S Materazzi, ...
The Journal of physiology 578 (3), 715-733, 2007
|Protease‐activated receptor 2 sensitizes TRPV1 by protein kinase Cɛ‐and A‐dependent mechanisms in rats and mice|
S Amadesi, GS Cottrell, L Divino, K Chapman, EF Grady, F Bautista, ...
The Journal of physiology 575 (2), 555-571, 2006
|Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo|
The Journal of Immunology 163 (9), 5064-5069, 1999
|Characterization of the inflammatory response to proteinase‐activated receptor‐2 (PAR2)‐activating peptides in the rat paw|
N Vergnolle, MD Hollenberg, KA Sharkey, JL Wallace
British journal of pharmacology 127 (5), 1083-1090, 1999
|Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats|
AM Coelho, N Vergnolle, B Guiard, J Fioramonti, L Bueno
Gastroenterology 122 (4), 1035-1047, 2002
|Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis|
S Fiorucci, A Mencarelli, B Palazzetti, E Distrutti, N Vergnolle, ...
Proceedings of the National Academy of Sciences 98 (24), 13936-13941, 2001
|Proteinase-activated receptor 2 (PAR2)-activating peptides: identification of a receptor distinct from PAR2 that regulates intestinal transport|
N Vergnolle, WK Macnaughton, B Al-Ani, M Saifeddine, JL Wallace, ...
Proceedings of the National Academy of Sciences 95 (13), 7766-7771, 1998
|A major role for proteolytic activity and proteinase-activated receptor-2 in the pathogenesis of infectious colitis|
KK Hansen, PM Sherman, L Cellars, P Andrade-Gordon, Z Pan, A Baruch, ...
Proceedings of the National Academy of Sciences 102 (23), 8363-8368, 2005
|Clinical relevance of proteinase activated receptors (pars) in the gut|
Gut 54 (6), 867-874, 2005
|Transient receptor potential vanilloid-4 has a major role in visceral hypersensitivity symptoms|
N Cenac, C Altier, K Chapman, W Liedtke, G Zamponi, N Vergnolle
Gastroenterology 135 (3), 937-946. e2, 2008
|Proteinase-activated receptor 1 activation induces epithelial apoptosis and increases intestinal permeability|
AC Chin, N Vergnolle, WK MacNaughton, JL Wallace, MD Hollenberg, ...
Proceedings of the National Academy of Sciences 100 (19), 11104-11109, 2003
|Proteinase-activated receptor-2-induced colonic inflammation in mice: possible involvement of afferent neurons, nitric oxide, and paracellular permeability|
N Cenac, R Garcia-Villar, L Ferrier, M Larauche, N Vergnolle, NW Bunnett, ...
The Journal of Immunology 170 (8), 4296-4300, 2003