| Inhibition of endosteal vascular niche remodeling rescues hematopoietic stem cell loss in AML D Duarte, ED Hawkins, O Akinduro, H Ang, K De Filippo, IY Kong, ... Cell stem cell 22 (1), 64-77. e6, 2018 | 288 | 2018 |
| Tumor immune evasion arises through loss of TNF sensitivity CJ Kearney, SJ Vervoort, SJ Hogg, KM Ramsbottom, AJ Freeman, ... Science immunology 3 (23), eaar3451, 2018 | 287 | 2018 |
| BET-bromodomain inhibitors engage the host immune system and regulate expression of the immune checkpoint ligand PD-L1 SJ Hogg, SJ Vervoort, S Deswal, CJ Ott, J Li, LA Cluse, PA Beavis, ... Cell reports 18 (9), 2162-2174, 2017 | 271 | 2017 |
| Modulation of glutamine metabolism by the PI (3) K–PKB–FOXO network regulates autophagy KE Van Der Vos, P Eliasson, T Proikas-Cezanne, SJ Vervoort, ... Nature cell biology 14 (8), 829-837, 2012 | 264 | 2012 |
| The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe? SJ Vervoort, R van Boxtel, PJ Coffer Oncogene 32 (29), 3397-3409, 2013 | 227 | 2013 |
| Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity J Lai, S Mardiana, IG House, K Sek, MA Henderson, L Giuffrida, ... Nature immunology 21 (8), 914-926, 2020 | 135 | 2020 |
| The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, S Offley, ... Cell 184 (12), 3143-3162. e32, 2021 | 115 | 2021 |
| SOX4 mediates TGF-β-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition SJ Vervoort, AR Lourenço, R van Boxtel, PJ Coffer PloS one 8 (1), e53238, 2013 | 111 | 2013 |
| Inhibition of super-enhancer activity in autoinflammatory site-derived T cells reduces disease-associated gene expression JGC Peeters, SJ Vervoort, SC Tan, G Mijnheer, S de Roock, SJ Vastert, ... Cell reports 12 (12), 1986-1996, 2015 | 104 | 2015 |
| CDK13 cooperates with CDK12 to control global RNA polymerase II processivity Z Fan, JR Devlin, SJ Hogg, MA Doyle, PF Harrison, I Todorovski, ... Science advances 6 (18), eaaz5041, 2020 | 102 | 2020 |
| Natural killer cells suppress T cell-associated tumor immune evasion AJ Freeman, SJ Vervoort, KM Ramsbottom, MJ Kelly, J Michie, L Pijpers, ... Cell reports 28 (11), 2784-2794. e5, 2019 | 86 | 2019 |
| Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition SJ Hogg, O Motorna, LA Cluse, TM Johanson, HD Coughlan, R Raviram, ... Molecular cell 81 (10), 2183-2200. e13, 2021 | 72 | 2021 |
| Antagonism of IAPs enhances CAR T-cell efficacy J Michie, PA Beavis, AJ Freeman, SJ Vervoort, KM Ramsbottom, ... Cancer immunology research 7 (2), 183-192, 2019 | 72 | 2019 |
| BET inhibition induces apoptosis in aggressive B-cell lymphoma via epigenetic regulation of BCL-2 family members SJ Hogg, A Newbold, SJ Vervoort, LA Cluse, BP Martin, GP Gregory, ... Molecular cancer therapeutics 15 (9), 2030-2041, 2016 | 72 | 2016 |
| CDK4/6 inhibition promotes antitumor immunity through the induction of T-cell memory EJ Lelliott, IY Kong, M Zethoven, KM Ramsbottom, LG Martelotto, ... Cancer discovery 11 (10), 2582-2601, 2021 | 69 | 2021 |
| Complexity and diversity of the mammalian sialome revealed by nidovirus virolectins MA Langereis, MJG Bakkers, L Deng, V Padler-Karavani, SJ Vervoort, ... Cell reports 11 (12), 1966-1978, 2015 | 67 | 2015 |
| Targeting transcription cycles in cancer SJ Vervoort, JR Devlin, N Kwiatkowski, M Teng, NS Gray, RW Johnstone Nature Reviews Cancer 22 (1), 5-24, 2022 | 65 | 2022 |
| IL-15 preconditioning augments CAR T cell responses to checkpoint blockade for improved treatment of solid tumors L Giuffrida, K Sek, MA Henderson, IG House, J Lai, AXY Chen, KL Todd, ... Molecular Therapy 28 (11), 2379-2393, 2020 | 63 | 2020 |
| FOXP1 promotes embryonic neural stem cell differentiation by repressing Jagged1 expression L Braccioli, SJ Vervoort, Y Adolfs, CJ Heijnen, O Basak, RJ Pasterkamp, ... Stem cell reports 9 (5), 1530-1545, 2017 | 63 | 2017 |
| Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis MJ Kelly, J So, AJ Rogers, G Gregory, J Li, M Zethoven, MD Gearhart, ... Nature communications 10 (1), 1347, 2019 | 56 | 2019 |
Simon J. HoggAbbVie, Memorial Sloan Kettering Cancer Center, Peter MacCallum Cancer CenterVerified email at abbvie.com
