|The cholinergic hypothesis of geriatric memory dysfunction|
RT Bartus, RL Dean, B Beer, AS Lippa
Science 217 (4558), 408-414, 1982
|Age‐associated memory impairment: Proposed diagnostic criteria and measures of clinical change—report of a national institute of mental health work group|
T Crook, RT Bartus, SH Ferris, P Whitehouse, GD Cohen, S Gershon
Taylor & Francis Group 2 (4), 261-276, 1986
|On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis|
Experimental neurology 163 (2), 495-529, 2000
|Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label …|
WJ Marks Jr, JL Ostrem, L Verhagen, PA Starr, PS Larson, RAE Bakay, ...
The Lancet Neurology 7 (5), 400-408, 2008
|The cholinergic hypothesis: a historical overview, current perspective, and future directions|
RT Bartus, RL Dean, MJ Pontecorvo, C Flicker
Annals of the New York Academy of Sciences 444 (1), 332-358, 1985
|Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial|
WJ Marks Jr, RT Bartus, J Siffert, CS Davis, A Lozano, N Boulis, J Vitek, ...
The Lancet Neurology 9 (12), 1164-1172, 2010
|Disease duration and the integrity of the nigrostriatal system in Parkinson’s disease|
JH Kordower, CW Olanow, HB Dodiya, Y Chu, TG Beach, CH Adler, ...
Brain 136 (8), 2419-2431, 2013
|Behavioral and neurochemical effects following neurotoxic lesions of a major cholinergic input to the cerebral cortex in the rat|
C Flicker, RL Dean, DL Watkins, SK Fisher, RT Bartus
Pharmacology Biochemistry and Behavior 18 (6), 973-981, 1983
|Short-term memory in the rhesus monkey: disruption from the anti-cholinergic scopolamine|
RT Bartus, HR Johnson
Pharmacology Biochemistry and Behavior 5 (1), 39-46, 1976
|Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses|
K Ikeda, T Ichikawa, H Wakimoto, JS Silver, TS Deisboeck, D Finkelstein, ...
Nature medicine 5 (8), 881, 1999
|Age-related changes in passive avoidance retention: modulation with dietary choline.|
RT Bartus, RL Dean, JA Goas, AS Lippa
|Aging in the rhesus monkey: debilitating effects on short-term memory|
RT Bartus, D Fleming, HR Johnson
Journal of Gerontology 33 (6), 858-871, 1978
|Selective memory loss following nucleus basalis lesions: long term behavioral recovery despite persistent cholinergic deficiencies|
RT Bartus, C Flicker, RL Dean, M Pontecorvo, JC Figueiredo, SK Fisher
Pharmacology Biochemistry and Behavior 23 (1), 125-135, 1985
|Brain cholinergic dysfunction and memory in aged rats|
AS Lippa, RW Pelham, B Beer, DJ Critchett, RL Dean, RT Bartus
Neurobiology of Aging 1 (1), 13-19, 1980
|Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat|
KE Saatman, H Murai, RT Bartus, DH Smith, NJ Hayward, BR Perri, ...
Proceedings of the National Academy of Sciences 93 (8), 3428-3433, 1996
|Age-related alterations in the rodent brain cholinergic system and behavior|
R Strong, P Hicks, L Hsu, RT Bartus, SJ Enna
Neurobiology of aging 1 (1), 59-63, 1980
|Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration.|
RT Bartus, NJ Hayward, PJ Elliott, SD Sawyer, KL Baker, RL Dean, ...
Stroke 25 (11), 2265-2270, 1994
|Physostigmine and recent memory: effects in young and aged nonhuman primates|
Science 206 (4422), 1087-1089, 1979
|Delivery of neurturin by AAV2 (CERE‐120)‐mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP‐treated monkeys|
JH Kordower, CD Herzog, B Dass, RAE Bakay, J Stansell, M Gasmi, ...
Annals of neurology 60 (6), 706-715, 2006
|Pulmonary delivery in treating disorders of the central nervous system|
RT Bartus, DF Emerich
US Patent 6,613,308, 2003