Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 7244 | 2021 |
Distinct Wnt signaling pathways have opposing roles in appendage regeneration CL Stoick-Cooper, G Weidinger, KJ Riehle, C Hubbert, MB Major, ... Development 134 (3), 479-489, 2007 | 524 | 2007 |
Wilms tumor suppressor WTX negatively regulates WNT/ß-catenin signaling MB Major, ND Camp, JD Berndt, XH Yi, SJ Goldenberg, C Hubbert, ... science 316 (5827), 1043-1046, 2007 | 438 | 2007 |
Activated Wnt/ß-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model AJ Chien, EC Moore, AS Lonsdorf, RM Kulikauskas, BG Rothberg, ... Proceedings of the National Academy of Sciences 106 (4), 1193-1198, 2009 | 371 | 2009 |
Colon cancer AM Cohen Principles and practice of oncology, 1993 | 268* | 1993 |
Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease GV De Ferrari, A Papassotiropoulos, T Biechele, FW De-Vrieze, ME Avila, ... Proceedings of the National Academy of Sciences 104 (22), 9434-9439, 2007 | 212 | 2007 |
The Kindler syndrome protein is regulated by transforming growth factor-β and involved in integrin-mediated adhesion S Kloeker, MB Major, DA Calderwood, MH Ginsberg, DA Jones, ... Journal of Biological Chemistry 279 (8), 6824-6833, 2004 | 202 | 2004 |
Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination BE Hast, D Goldfarb, KM Mulvaney, MA Hast, PF Siesser, F Yan, ... Cancer research 73 (7), 2199-2210, 2013 | 189 | 2013 |
New regulators of Wnt/β-catenin signaling revealed by integrative molecular screening MB Major, BS Roberts, JD Berndt, S Marine, J Anastas, N Chung, ... Science signaling 1 (45), ra12-ra12, 2008 | 150 | 2008 |
Small-molecule synergist of the Wnt/β-catenin signaling pathway Q Zhang, MB Major, S Takanashi, ND Camp, N Nishiya, EC Peters, ... Proceedings of the National Academy of Sciences 104 (18), 7444-7448, 2007 | 147 | 2007 |
Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination BE Hast, EW Cloer, D Goldfarb, H Li, PF Siesser, F Yan, V Walter, ... Cancer research 74 (3), 808-817, 2014 | 106 | 2014 |
WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma MD Arensman, AN Kovochich, RM Kulikauskas, AR Lay, PT Yang, X Li, ... Oncogene 33 (7), 899-908, 2014 | 96 | 2014 |
Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein ND Camp, RG James, DW Dawson, F Yan, JM Davison, SA Houck, ... Journal of Biological Chemistry 287 (9), 6539-6550, 2012 | 96 | 2012 |
BRG1/SMARCA4 inactivation promotes non–small cell lung cancer aggressiveness by altering chromatin organization T Orvis, A Hepperla, V Walter, S Song, J Simon, J Parker, MD Wilkerson, ... Cancer research 74 (22), 6486-6498, 2014 | 92 | 2014 |
WIKI4, a novel inhibitor of tankyrase and Wnt/ss-catenin signaling RG James, KC Davidson, KA Bosch, TL Biechele, NC Robin, RJ Taylor, ... PloS one 7 (12), e50457, 2012 | 82 | 2012 |
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 JS Harrison, EM Cornett, D Goldfarb, PA DaRosa, ZM Li, F Yan, ... elife 5, e17101, 2016 | 79 | 2016 |
USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds B Madan, MP Walker, R Young, L Quick, KA Orgel, M Ryan, P Gupta, ... Proceedings of the National Academy of Sciences 113 (21), E2945-E2954, 2016 | 61 | 2016 |
NRF2 activation in cancer: from DNA to protein EW Cloer, D Goldfarb, TP Schrank, BE Weissman, MB Major Cancer research 79 (5), 889-898, 2019 | 59 | 2019 |
Bruton’s Tyrosine Kinase Revealed as a Negative Regulator of Wnt–β-Catenin Signaling RG James, TL Biechele, WH Conrad, ND Camp, DM Fass, MB Major, ... Science signaling 2 (72), ra25-ra25, 2009 | 57 | 2009 |
Glycosylation of KEAP 1 links nutrient sensing to redox stress signaling PH Chen, TJ Smith, J Wu, PF Siesser, BJ Bisnett, F Khan, M Hogue, ... The EMBO journal 36 (15), 2233-2250, 2017 | 52 | 2017 |