Jeff Holst
Jeff Holst
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Orchestrated intron retention regulates normal granulocyte differentiation
JJL Wong, W Ritchie, OA Ebner, M Selbach, JWH Wong, Y Huang, D Gao, ...
Cell 154 (3), 583-595, 2013
ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer
M Van Geldermalsen, Q Wang, R Nagarajah, AD Marshall, A Thoeng, ...
Oncogene 35 (24), 3201-3208, 2016
Generation of T-cell receptor retrogenic mice
J Holst, AL Szymczak-Workman, KM Vignali, AR Burton, CJ Workman, ...
Nature protocols 1 (1), 406-417, 2006
Distinct immune cell populations define response to anti-PD-1 monotherapy and anti-PD-1/anti-CTLA-4 combined therapy
TN Gide, C Quek, AM Menzies, AT Tasker, P Shang, J Holst, J Madore, ...
Cancer cell 35 (2), 238-255. e6, 2019
Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells
J Holst, S Watson, MS Lord, SS Eamegdool, DV Bax, LB Nivison-Smith, ...
Nature biotechnology 28 (10), 1123-1128, 2010
Targeting ASCT2‐mediated glutamine uptake blocks prostate cancer growth and tumour development
Q Wang, RA Hardie, AJ Hoy, M Van Geldermalsen, D Gao, L Fazli, ...
The Journal of pathology 236 (3), 278-289, 2015
General nature of the STAT3-activated anti-inflammatory response
KC El Kasmi, J Holst, M Coffre, L Mielke, A De Pauw, N Lhocine, ...
The Journal of Immunology 177 (11), 7880-7888, 2006
Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration
S Balaban, RF Shearer, LS Lee, M van Geldermalsen, M Schreuder, ...
Cancer & metabolism 5 (1), 1-14, 2017
L-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasia
Q Wang, J Holst
American journal of cancer research 5 (4), 1281, 2015
Targeting glutamine transport to suppress melanoma cell growth
Q Wang, KA Beaumont, NJ Otte, J Font, CG Bailey, M van Geldermalsen, ...
International journal of cancer 135 (5), 1060-1071, 2014
Nuclear-localized tiny RNAs are associated with transcription initiation and splice sites in metazoans
RJ Taft, C Simons, S Nahkuri, H Oey, DJ Korbie, TR Mercer, J Holst, ...
Nature structural & molecular biology 17 (8), 1030-1034, 2010
Rapid analysis of T-cell selection in vivo using T cell–receptor retrogenic mice
J Holst, KM Vignali, AR Burton, DAA Vignali
Nature methods 3 (3), 191-197, 2006
Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development
Q Wang, J Tiffen, CG Bailey, ML Lehman, W Ritchie, L Fazli, C Metierre, ...
Journal of the National Cancer Institute 105 (19), 1463-1473, 2013
Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression
Q Wang, CG Bailey, C Ng, J Tiffen, A Thoeng, V Minhas, ML Lehman, ...
Cancer research 71 (24), 7525-7536, 2011
Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity
J Holst, H Wang, KD Eder, CJ Workman, KL Boyd, Z Baquet, H Singh, ...
Nature immunology 9 (6), 658-666, 2008
Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia
S Flamant, W Ritchie, J Guilhot, J Holst, ML Bonnet, JC Chomel, F Guilhot, ...
Haematologica 95 (8), 1325, 2010
Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo
JC Tiffen, CG Bailey, C Ng, JEJ Rasko, J Holst
Molecular cancer 9 (1), 1-8, 2010
p27Kip1 signaling: Transcriptional and post-translational regulation
SST Hnit, C Xie, M Yao, J Holst, A Bensoussan, P De Souza, Z Li, Q Dong
The International Journal of Biochemistry & Cell Biology 68, 9-14, 2015
Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse
A Bröer, T Juelich, JM Vanslambrouck, N Tietze, PS Solomon, J Holst, ...
Journal of Biological Chemistry 286 (30), 26638-26651, 2011
Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment
JJL Wong, D Gao, TV Nguyen, CT Kwok, M van Geldermalsen, ...
Nature communications 8 (1), 1-13, 2017
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