The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma PA Pérez-Mancera, AG Rust, L Van Der Weyden, G Kristiansen, A Li, ... Nature 486 (7402), 266-270, 2012 | 343 | 2012 |
Non-injection methods for the production of embryonic stem cell-embryo chimaeras SA Wood, ND Allen, J Rossant, A Auerbach, A Nagy Nature 365 (6441), 87-89, 1993 | 340 | 1993 |
The Vps35 D620N mutation linked to Parkinson's disease disrupts the cargo sorting function of retromer J Follett, SJ Norwood, NA Hamilton, M Mohan, O Kovtun, S Tay, Y Zhe, ... Traffic 15 (2), 230-244, 2014 | 247 | 2014 |
Disease-specific, neurosphere-derived cells as models for brain disorders N Matigian, G Abrahamsen, R Sutharsan, AL Cook, AM Vitale, ... Disease models & mechanisms 3 (11-12), 785-798, 2010 | 221 | 2010 |
La FAM fatale: USP9X in development and disease M Murtaza, LA Jolly, J Gecz, SA Wood Cellular and molecular life sciences 72, 2075-2089, 2015 | 186 | 2015 |
Simple and efficient production of embryonic stem cell-embryo chimeras by coculture. SA Wood, WS Pascoe, C Schmidt, R Kemler, MJ Evans, ND Allen Proceedings of the National Academy of Sciences 90 (10), 4582-4585, 1993 | 186 | 1993 |
The deubiquitinating enzyme Fam interacts with and stabilizes β‐catenin S Taya, T Yamamoto, M Kanai‐Azuma, SA Wood, K Kaibuchi Genes to Cells 4 (12), 757-767, 1999 | 184 | 1999 |
Effects of epidermal growth factor on preimplantation mouse embryos SA Wood, PL Kaye Reproduction 85 (2), 575-582, 1989 | 179 | 1989 |
The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X R Mouchantaf, BA Azakir, PS McPherson, SM Millard, SA Wood, A Angers Journal of Biological Chemistry 281 (50), 38738-38747, 2006 | 159 | 2006 |
The Ras target AF-6 is a substrate of the fam deubiquitinating enzyme S Taya, T Yamamoto, K Kano, Y Kawano, A Iwamatsu, T Tsuchiya, ... The Journal of cell biology 142 (4), 1053-1062, 1998 | 155 | 1998 |
Gene knock-out technology: a methodological overview for the interested novice LA Galli-Taliadoros, JD Sedgwick, SA Wood, H Körner Journal of immunological methods 181 (1), 1-15, 1995 | 148 | 1995 |
Mutations in USP9X are associated with X-linked intellectual disability and disrupt neuronal cell migration and growth CC Homan, R Kumar, LS Nguyen, E Haan, FL Raymond, F Abidi, ... The American Journal of Human Genetics 94 (3), 470-478, 2014 | 145 | 2014 |
The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and β-catenin RZ Murray, LA Jolly, SA Wood Molecular biology of the cell 15 (4), 1591-1599, 2004 | 125 | 2004 |
Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate CP Grou, T Francisco, TA Rodrigues, MO Freitas, MP Pinto, AF Carvalho, ... Journal of Biological Chemistry 287 (16), 12815-12827, 2012 | 121 | 2012 |
NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease AL Cook, AM Vitale, S Ravishankar, N Matigian, GT Sutherland, J Shan, ... PloS one 6 (7), e21907, 2011 | 114 | 2011 |
Cloning and expression analysis of a novel mouse gene with sequence similarity to the Drosophila fat facets gene SA Wood, WS Pascoe, KL Ru, T Yamada, J Hirchenhain, R Kemler, ... Mechanisms of development 63 (1), 29-38, 1997 | 113 | 1997 |
The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X JA Nathan, S Sengupta, SA Wood, A Admon, G Markson, C Sanderson, ... Traffic 9 (7), 1130-1145, 2008 | 105 | 2008 |
De novo loss-of-function mutations in USP9X cause a female-specific recognizable syndrome with developmental delay and congenital malformations MRF Reijnders, V Zachariadis, B Latour, L Jolly, GM Mancini, R Pfundt, ... The American Journal of Human Genetics 98 (2), 373-381, 2016 | 94 | 2016 |
The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer OM Khan, J Carvalho, B Spencer-Dene, R Mitter, D Frith, AP Snijders, ... The Journal of clinical investigation 128 (4), 1326-1337, 2018 | 90 | 2018 |
Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis S Stegeman, LA Jolly, S Premarathne, J Gecz, LJ Richards, ... PloS one 8 (7), e68287, 2013 | 88 | 2013 |