James Whisstock
James Whisstock
Monash University, ARC Centre of Excellence in Advanced Molecular Imaging, EMBL Australia
Verified email at monash.edu
TitleCited byYear
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins evolution, mechanism of inhibition, novel functions, and a revised nomenclature
GA Silverman, PI Bird, RW Carrell, FC Church, PB Coughlin, PGW Gettins, ...
Journal of Biological Chemistry 276 (36), 33293-33296, 2001
13222001
Prediction of protein function from protein sequence and structure
JC Whisstock, AM Lesk
Quarterly reviews of biophysics 36 (3), 307-340, 2003
7132003
Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function
JA Irving, RN Pike, AM Lesk, JC Whisstock
Genome research 10 (12), 1845-1864, 2000
6472000
MUSTANG: a multiple structural alignment algorithm
AS Konagurthu, JC Whisstock, PJ Stuckey, AM Lesk
Proteins: Structure, Function, and Bioinformatics 64 (3), 559-574, 2006
6202006
An overview of the serpin superfamily
RHP Law, Q Zhang, S McGowan, AM Buckle, GA Silverman, W Wong, ...
Genome biology 7 (5), 216, 2006
4962006
A structural basis for the selection of dominant αβ T cell receptors in antiviral immunity
L Kjer-Nielsen, CS Clements, AW Purcell, AG Brooks, JC Whisstock, ...
Immunity 18 (1), 53-64, 2003
3572003
Perforin and granzymes: function, dysfunction and human pathology
I Voskoboinik, JC Whisstock, JA Trapani
Nature Reviews Immunology 15 (6), 388, 2015
3112015
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP
AW Paton, T Beddoe, CM Thorpe, JC Whisstock, MCJ Wilce, J Rossjohn, ...
Nature 443 (7111), 548, 2006
3072006
The structural basis for membrane binding and pore formation by lymphocyte perforin
RHP Law, N Lukoyanova, I Voskoboinik, TT Caradoc-Davies, K Baran, ...
Nature 468 (7322), 447, 2010
2912010
T cell receptor recognition of a'super-bulged'major histocompatibility complex class I–bound peptide
FE Tynan, SR Burrows, AM Buckle, CS Clements, NA Borg, JJ Miles, ...
Nature immunology 6 (11), 1114, 2005
2642005
A common fold mediates vertebrate defense and bacterial attack
CJ Rosado, AM Buckle, RHP Law, RE Butcher, WT Kan, CH Bird, K Ung, ...
Science 317 (5844), 1548-1551, 2007
2462007
Conservation within the myosin motor domain: implications for structure and function
MJTV Cope, J Whisstock, I Rayment, J Kendrick-Jones
Structure 4 (8), 969-987, 1996
2431996
Glycoprotein Ib–IX–V
RK Andrews, EE Gardiner, Y Shen, JC Whisstock, MC Berndt
The international journal of biochemistry & cell biology 35 (8), 1170-1174, 2003
2352003
The MACPF/CDC family of pore‐forming toxins
CJ Rosado, S Kondos, TE Bull, MJ Kuiper, RHP Law, AM Buckle, ...
Cellular microbiology 10 (9), 1765-1774, 2008
2282008
Perforin: structure, function, and role in human immunopathology
I Voskoboinik, MA Dunstone, K Baran, JC Whisstock, JA Trapani
Immunological reviews 235 (1), 35-54, 2010
2232010
An atlas of serpin conformations
J Whisstock, R Skinner, AM Lesk
Trends in biochemical sciences 23 (2), 63-67, 1998
2131998
The 2.6 structure of antithrombin indicates a conformational change at the heparin binding site
R Skinner, JP Abrahams, JC Whisstock, AM Lesk, RW Carrell, ...
Journal of molecular biology 266 (3), 601-609, 1997
2111997
The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-κB p65
HJ Newton, JS Pearson, L Badea, M Kelly, M Lucas, G Holloway, ...
PLoS pathogens 6 (5), e1000898, 2010
2002010
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
CA Nold-Petry, CY Lo, I Rudloff, KD Elgass, S Li, MP Gantier, ...
Nature immunology 16 (4), 354, 2015
1862015
Functional insights from the distribution and role of homopeptide repeat-containing proteins
NG Faux, SP Bottomley, AM Lesk, JA Irving, JR Morrison, ...
Genome research 15 (4), 537-551, 2005
1732005
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Articles 1–20