Genotoxic lipid peroxidation products: their DNA damaging properties and role in formation of endogenous DNA adducts PC Burcham Mutagenesis 13 (3), 287-305, 1998 | 394 | 1998 |
Endogenous DNA adducts: potential and paradox LJ Marnett, PC Burcham Chemical research in toxicology 6 (6), 771-785, 1993 | 369 | 1993 |
Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes. PC Burcham, AW Harman Journal of Biological Chemistry 266 (8), 5049-5054, 1991 | 299 | 1991 |
Cylindrospermopsin‐induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes SM Froscio, AR Humpage, PC Burcham, IR Falconer Environmental Toxicology: An International Journal 18 (4), 243-251, 2003 | 298 | 2003 |
Cylindrospermopsin genotoxicity and cytotoxicity: Role of cytochrome P-450 and oxidative stress AR Humpage, F Fontaine, S Froscio, P Burcham, IR Falconer Journal of Toxicology and Environmental Health, Part A 68 (9), 739-753, 2005 | 242 | 2005 |
Introduction of carbonyl groups into proteins by the lipid peroxidation product, malondialdehyde PC Burcham, YT Kuhan Biochemical and Biophysical Research Communications 220 (3), 996-1001, 1996 | 182 | 1996 |
Internal hazards: baseline DNA damage by endogenous products of normal metabolism PC Burcham Mutation Research/Genetic Toxicology and Environmental Mutagenesis 443 (1-2 …, 1999 | 172 | 1999 |
Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products PC Burcham, LM Kaminskas, FR Fontaine, DR Petersen, SM Pyke Toxicology 181, 229-236, 2002 | 144 | 2002 |
Abasic Sites Stimulate Double-stranded DNA Cleavage Mediated by Topoisomerase II: DNA LESIONS AS ENDOGENOUS TOPOISOMERASE II POISONS (∗) PS Kingma, AH Corbett, PC Burcham, LJ Marnett, N Osheroff Journal of Biological Chemistry 270 (37), 21441-21444, 1995 | 133 | 1995 |
Hydralazine inhibits rapid acrolein-induced protein oligomerization: role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection PC Burcham, SM Pyke Molecular pharmacology 69 (3), 1056-1065, 2006 | 111 | 2006 |
Cell‐free protein synthesis inhibition assay for the cyanobacterial toxin cylindrospermopsin SM Froscio, AR Humpage, PC Burcham, IR Falconer Environmental Toxicology: An International Journal 16 (5), 408-412, 2001 | 111 | 2001 |
Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice LM Kaminskas, SM Pyke, PC Burcham Journal of Pharmacology and Experimental Therapeutics 310 (3), 1003-1010, 2004 | 106 | 2004 |
Inactivation of glutathione peroxidase activity contributes to UV-induced squamous cell carcinoma formation J Walshe, MM Serewko-Auret, N Teakle, S Cameron, K Minto, L Smith, ... Cancer research 67 (10), 4751-4758, 2007 | 90 | 2007 |
The antihypertensive hydralazine is an efficient scavenger of acrolein PC Burcham, PG Kerr, F Fontaine Redox Report 5 (1), 47-49, 2000 | 82 | 2000 |
Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity PC Burcham, FR Fontaine, LM Kaminskas, DR Petersen, SM Pyke Molecular pharmacology 65 (3), 655-664, 2004 | 77 | 2004 |
Mitochondrial dysfunction in paracetamol hepatotoxicity: in vitro studies in isolated mouse hepatocytes PC Burcham, AW Harman Toxicology letters 50 (1), 37-48, 1990 | 74 | 1990 |
Genome-wide transcriptional responses to acrolein CA Thompson, PC Burcham Chemical Research in Toxicology 21 (12), 2245-2256, 2008 | 70 | 2008 |
Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: a novel role for phase-II-mediated bioactivation in the hepatocarcinogenicity of the … BC Sallustio, LA Harkin, MC Mann, SJ Krivickas, PC Burcham Toxicology and applied pharmacology 147 (2), 459-464, 1997 | 68 | 1997 |
Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde LM Kaminskas, SM Pyke, PC Burcham Organic & biomolecular chemistry 2 (18), 2578-2584, 2004 | 67 | 2004 |
Site-specific mutagenesis by a propanodeoxyguanosine adduct carried on an M13 genome. PC Burcham, LJ Marnett Journal of Biological Chemistry 269 (46), 28844-28850, 1994 | 67 | 1994 |