Follow
Philip Burcham
Philip Burcham
Associate Professor of Pharmacology & Toxicology, University of Western Australia
Verified email at uwa.edu.au
Title
Cited by
Cited by
Year
Genotoxic lipid peroxidation products: their DNA damaging properties and role in formation of endogenous DNA adducts
PC Burcham
Mutagenesis 13 (3), 287-305, 1998
3941998
Endogenous DNA adducts: potential and paradox
LJ Marnett, PC Burcham
Chemical research in toxicology 6 (6), 771-785, 1993
3691993
Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes.
PC Burcham, AW Harman
Journal of Biological Chemistry 266 (8), 5049-5054, 1991
2991991
Cylindrospermopsin‐induced protein synthesis inhibition and its dissociation from acute toxicity in mouse hepatocytes
SM Froscio, AR Humpage, PC Burcham, IR Falconer
Environmental Toxicology: An International Journal 18 (4), 243-251, 2003
2982003
Cylindrospermopsin genotoxicity and cytotoxicity: Role of cytochrome P-450 and oxidative stress
AR Humpage, F Fontaine, S Froscio, P Burcham, IR Falconer
Journal of Toxicology and Environmental Health, Part A 68 (9), 739-753, 2005
2422005
Introduction of carbonyl groups into proteins by the lipid peroxidation product, malondialdehyde
PC Burcham, YT Kuhan
Biochemical and Biophysical Research Communications 220 (3), 996-1001, 1996
1821996
Internal hazards: baseline DNA damage by endogenous products of normal metabolism
PC Burcham
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 443 (1-2 …, 1999
1721999
Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products
PC Burcham, LM Kaminskas, FR Fontaine, DR Petersen, SM Pyke
Toxicology 181, 229-236, 2002
1442002
Abasic Sites Stimulate Double-stranded DNA Cleavage Mediated by Topoisomerase II: DNA LESIONS AS ENDOGENOUS TOPOISOMERASE II POISONS (∗)
PS Kingma, AH Corbett, PC Burcham, LJ Marnett, N Osheroff
Journal of Biological Chemistry 270 (37), 21441-21444, 1995
1331995
Hydralazine inhibits rapid acrolein-induced protein oligomerization: role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection
PC Burcham, SM Pyke
Molecular pharmacology 69 (3), 1056-1065, 2006
1112006
Cell‐free protein synthesis inhibition assay for the cyanobacterial toxin cylindrospermopsin
SM Froscio, AR Humpage, PC Burcham, IR Falconer
Environmental Toxicology: An International Journal 16 (5), 408-412, 2001
1112001
Strong protein adduct trapping accompanies abolition of acrolein-mediated hepatotoxicity by hydralazine in mice
LM Kaminskas, SM Pyke, PC Burcham
Journal of Pharmacology and Experimental Therapeutics 310 (3), 1003-1010, 2004
1062004
Inactivation of glutathione peroxidase activity contributes to UV-induced squamous cell carcinoma formation
J Walshe, MM Serewko-Auret, N Teakle, S Cameron, K Minto, L Smith, ...
Cancer research 67 (10), 4751-4758, 2007
902007
The antihypertensive hydralazine is an efficient scavenger of acrolein
PC Burcham, PG Kerr, F Fontaine
Redox Report 5 (1), 47-49, 2000
822000
Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity
PC Burcham, FR Fontaine, LM Kaminskas, DR Petersen, SM Pyke
Molecular pharmacology 65 (3), 655-664, 2004
772004
Mitochondrial dysfunction in paracetamol hepatotoxicity: in vitro studies in isolated mouse hepatocytes
PC Burcham, AW Harman
Toxicology letters 50 (1), 37-48, 1990
741990
Genome-wide transcriptional responses to acrolein
CA Thompson, PC Burcham
Chemical Research in Toxicology 21 (12), 2245-2256, 2008
702008
Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: a novel role for phase-II-mediated bioactivation in the hepatocarcinogenicity of the …
BC Sallustio, LA Harkin, MC Mann, SJ Krivickas, PC Burcham
Toxicology and applied pharmacology 147 (2), 459-464, 1997
681997
Reactivity of hydrazinophthalazine drugs with the lipid peroxidation products acrolein and crotonaldehyde
LM Kaminskas, SM Pyke, PC Burcham
Organic & biomolecular chemistry 2 (18), 2578-2584, 2004
672004
Site-specific mutagenesis by a propanodeoxyguanosine adduct carried on an M13 genome.
PC Burcham, LJ Marnett
Journal of Biological Chemistry 269 (46), 28844-28850, 1994
671994
The system can't perform the operation now. Try again later.
Articles 1–20