Graham Leggatt
Graham Leggatt
University of Queensland Diamantina Institute
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Selective expansion of high-or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
MA Alexander-Miller, GR Leggatt, JA Berzofsky
Proceedings of the National Academy of Sciences 93 (9), 4102-4107, 1996
Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL.
MA Alexander-Miller, GR Leggatt, A Sarin, JA Berzofsky
The Journal of experimental medicine 184 (2), 485-492, 1996
Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives
NA Saunders, F Simpson, EW Thompson, MM Hill, L Endo‐Munoz, ...
EMBO molecular medicine 4 (8), 675-684, 2012
Antigen-specific CD4+ T-cell help is required to activate a memory CD8+ T cell to a fully functional tumor killer cell
FG Gao, V Khammanivong, WJ Liu, GR Leggatt, IH Frazer, GJP Fernando
Cancer research 62 (22), 6438-6441, 2002
Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
P Bhat, G Leggatt, N Waterhouse, IH Frazer
Cell death & disease 8 (6), e2836-e2836, 2017
Potential strategies utilised by papillomavirus to evade host immunity
IH Frazer, R Thomas, J Zhou, GR Leggatt, L Dunn, N McMillan, RW Tindle, ...
Immunological reviews 168 (1), 131-142, 1999
Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes
W Gu, L Putral, K Hengst, K Minto, NA Saunders, G Leggatt, NAJ McMillan
Cancer gene therapy 13 (11), 1023-1032, 2006
RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin
LN Putral, MJ Bywater, W Gu, NA Saunders, BG Gabrielli, GR Leggatt, ...
Molecular pharmacology 68 (5), 1311-1319, 2005
Prevention and treatment of papillomavirus-related cancers through immunization
IH Frazer, GR Leggatt, SR Mattarollo
Annual review of immunology 29, 111-138, 2011
Serological evaluation of the 12 kDa subunit of antigen B in Echinococcus granulosus cyst fluid by immunoblot analysis
GR Leggatt, W Yang, DP McManus
Transactions of the Royal Society of Tropical Medicine and Hygiene 86 (2 …, 1992
Polynucleotide viral vaccines: codon optimisation and ubiquitin conjugation enhances prophylactic and therapeutic efficacy
WJ Liu, KN Zhao, FG Gao, GR Leggatt, GJP Fernando, IH Frazer
Vaccine 20 (5-6), 862-869, 2001
Regulation of immune responses to HPVinfection and during HPV‐directed immunotherapy
P Bhat, SR Mattarollo, C Gosmann, IH Frazer, GR Leggatt
Immunological reviews 239 (1), 85-98, 2011
Papillomavirus virus-like particles for the delivery of multiple cytotoxic T cell epitopes
WJ Liu, XS Liu, KN Zhao, GR Leggatt, IH Frazer
Virology 273 (2), 374-382, 2000
Chimeric human papilloma virus–simian/human immunodeficiency virus virus-like-particle vaccines: immunogenicity and protective efficacy in macaques
CJ Dale, XS Liu, R De Rose, DFJ Purcell, J Anderson, Y Xu, GR Leggatt, ...
Virology 301 (1), 176-187, 2002
Impaired antigen presentation and effectiveness of combined active/passive immunotherapy for epithelial tumors
K Matsumoto, GR Leggatt, J Zhong, X Liu, RL de Kluyver, T Peters, ...
Journal of the National Cancer Institute 96 (21), 1611-1619, 2004
Time to change perspectives on HPV in oropharyngeal cancer. A systematic review of HPV prevalence per oropharyngeal sub-site the last 3 years
L Haeggblom, T Ramqvist, M Tommasino, T Dalianis, A Näsman
Papillomavirus Research 4, 1-11, 2017
Tolerance or immunity to a tumor antigen expressed in somatic cells can be determined by systemic proinflammatory signals at the time of first antigen exposure
IH Frazer, R De Kluyver, GR Leggatt, HY Guo, L Dunn, O White, C Harris, ...
The Journal of Immunology 167 (11), 6180-6187, 2001
Invariant NKT cells in hyperplastic skin induce a local immune suppressive environment by IFN-γ production
SR Mattarollo, A Rahimpour, A Choyce, DI Godfrey, GR Leggatt, IH Frazer
The journal of immunology 184 (3), 1242-1250, 2010
Identification and diagnostic value of a major antibody epitope on the 12 kDa antigen from Echinococcus granulosus (hydatid disease) cyst fluid
GR Leggatt, DP McManus
Parasite immunology 16 (2), 87-96, 1994
Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes
IH Frazer, GJP Fernando, N Fowler, GR Leggatt, PF Lambert, A Liem, ...
European journal of immunology 28 (9), 2791-2800, 1998
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