Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair J Duan, C Gherghe, D Liu, E Hamlett, L Srikantha, L Rodgers, JN Regan, ... The EMBO journal 31 (2), 429-442, 2012 | 347 | 2012 |
Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome ED Hamlett, EJ Goetzl, A Ledreux, V Vasilevko, HA Boger, A LaRosa, ... Alzheimer's & Dementia 13 (5), 541-549, 2017 | 119 | 2017 |
Exosomal biomarkers in Down syndrome and Alzheimer's disease ED Hamlett, A Ledreux, H Potter, HJ Chial, D Patterson, JM Espinosa, ... Free Radical Biology and Medicine 114, 110-121, 2018 | 78 | 2018 |
Designer receptors enhance memory in a mouse model of Down syndrome AM Fortress, ED Hamlett, EM Vazey, G Aston-Jones, WA Cass, HA Boger, ... Journal of Neuroscience 35 (4), 1343-1353, 2015 | 73 | 2015 |
Neuronally derived extracellular vesicles: an emerging tool for understanding Alzheimer’s disease LS Watson, ED Hamlett, TD Stone, C Sims-Robinson Molecular Neurodegeneration 14, 1-9, 2019 | 60 | 2019 |
Alpha-lipoic acid supplementation protects enzymes from damage by nitrosative and oxidative stress S Hiller, R DeKroon, ED Hamlett, L Xu, C Osorio, J Robinette, W Winnik, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (1), 36-45, 2016 | 49 | 2016 |
RvE1 treatment prevents memory loss and neuroinflammation in the Ts65Dn mouse model of Down syndrome ED Hamlett, E Hjorth, A Ledreux, A Gilmore, M Schultzberg, AC Granholm Glia 68 (7), 1347-1360, 2020 | 32 | 2020 |
Diggin′ on U (biquitin): a novel method for the identification of physiological E3 ubiquitin ligase substrates CE Rubel, JC Schisler, ED Hamlett, RM DeKroon, M Gautel, O Alzate, ... Cell biochemistry and biophysics 67, 127-138, 2013 | 25 | 2013 |
Incorporating sequence information into the scoring function: a hidden Markov model for improved peptide identification J Khatun, E Hamlett, MC Giddings Bioinformatics 24 (5), 674-681, 2008 | 23 | 2008 |
Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue L Lemoine, A Ledreux, EJ Mufson, SE Perez, G Simic, E Doran, I Lott, ... Molecular neurodegeneration 15, 1-10, 2020 | 22 | 2020 |
Analysis of proteins using DIGE and MALDI mass spectrometry WM Winnik, RM DeKroon, JSY Jeong, M Mocanu, JB Robinette, C Osorio, ... Difference Gel Electrophoresis (DIGE) Methods and Protocols, 47-66, 2012 | 17 | 2012 |
Suppression of Fli-1 protects against pericyte loss and cognitive deficits in Alzheimer's disease P Li, Y Wu, ED Hamlett, AJ Goodwin, PV Halushka, SL Carroll, M Liu, ... Molecular Therapy 30 (4), 1451-1464, 2022 | 16 | 2022 |
Small neuron-derived extracellular vesicles from individuals with Down syndrome propagate tau pathology in the wildtype mouse brain A Ledreux, S Thomas, ED Hamlett, C Trautman, A Gilmore, ... Journal of clinical medicine 10 (17), 3931, 2021 | 16 | 2021 |
Exosome release and cargo in Down syndrome ED Hamlett, A LaRosa, EJ Mufson, J Fortea, A Ledreux, AC Granholm Developmental neurobiology 79 (7), 639-655, 2019 | 16 | 2019 |
Evidence of altered age-related brain cytoarchitecture in mouse models of down syndrome: a diffusional kurtosis imaging study X Nie, ED Hamlett, AC Granholm, ES Hui, JA Helpern, JH Jensen, ... Magnetic resonance imaging 33 (4), 437-447, 2015 | 15 | 2015 |
High-accuracy peptide mass fingerprinting using peak intensity data with machine learning D Yang, K Ramkissoon, E Hamlett, MC Giddings Journal of Proteome Research 7 (01), 62-69, 2008 | 13 | 2008 |
Inhibitory designer receptors aggravate memory loss in a mouse model of down syndrome ED Hamlett, A Ledreux, A Gilmore, EM Vazey, G Aston-Jones, HA Boger, ... Neurobiology of disease 134, 104616, 2020 | 10 | 2020 |
Analysis of protein posttranslational modifications using DIGE-based proteomics RM DeKroon, JB Robinette, C Osorio, JSY Jeong, E Hamlett, M Mocanu, ... Difference Gel Electrophoresis (DIGE) Methods and Protocols, 129-143, 2012 | 10 | 2012 |
p38 MAPK is a major regulator of amyloid beta-induced IL-6 expression in human microglia H Lin, SG Dixon, W Hu, ED Hamlett, J Jin, A Ergul, GY Wang Molecular neurobiology 59 (9), 5284-5298, 2022 | 9 | 2022 |
Chronic cannabis smoking-enriched oral pathobiont drives behavioral changes, macrophage infiltration, and increases β-amyloid protein production in the brain Z Luo, S Fitting, C Robinson, A Benitez, M Li, Y Wu, X Fu, D Amato, ... EBioMedicine 74, 2021 | 9 | 2021 |