| Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors D Leung, K Schroder, H White, NX Fang, MJ Stoermer, G Abbenante, ... Journal of Biological Chemistry 276 (49), 45762-45771, 2001 | 384 | 2001 |
| Orally absorbed cyclic peptides DS Nielsen, NE Shepherd, W Xu, AJ Lucke, MJ Stoermer, DP Fairlie Chemical reviews 117 (12), 8094-8128, 2017 | 322 | 2017 |
| Flavones are inhibitors of HIV-1 proteinase RI Brinkworth, MJ Stoermer, DP Fairlie Biochemical and biophysical research communications 188 (2), 631-637, 1992 | 183 | 1992 |
| Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria KT Andrews, DP Fairlie, PK Madala, J Ray, DM Wyatt, PM Hilton, ... Antimicrobial agents and chemotherapy 50 (2), 639-648, 2006 | 164 | 2006 |
| Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation G Robin, K Chappell, MJ Stoermer, SH Hu, PR Young, DP Fairlie, ... Journal of molecular biology 385 (5), 1568-1577, 2009 | 162 | 2009 |
| Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease TA Nall, KJ Chappell, MJ Stoermer, NX Fang, JDA Tyndall, PR Young, ... Journal of Biological Chemistry 279 (47), 48535-48542, 2004 | 141 | 2004 |
| Potent cyclic antagonists of the complement C5a receptor on human polymorphonuclear leukocytes. Relationships between structures and activity DR March, LM Proctor, MJ Stoermer, R Sbaglia, G Abbenante, RC Reid, ... Molecular pharmacology 65 (4), 868-879, 2004 | 132 | 2004 |
| In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses T Kampmann, R Yennamalli, P Campbell, MJ Stoermer, DP Fairlie, ... Antiviral research 84 (3), 234-241, 2009 | 122 | 2009 |
| West Nile Virus NS2B/NS3 protease as an antiviral target KJ Chappell, MJ Stoermer, DP Fairlie, PR Young Current medicinal chemistry 15 (27), 2771-2784, 2008 | 106 | 2008 |
| Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity MJ Stoermer, KJ Chappell, S Liebscher, CM Jensen, CH Gan, PK Gupta, ... Journal of medicinal chemistry 51 (18), 5714-5721, 2008 | 93 | 2008 |
| Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies KJ Chappell, MJ Stoermer, DP Fairlie, PR Young Journal of Biological Chemistry 281 (50), 38448-38458, 2006 | 93 | 2006 |
| Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity KJ Chappell, MJ Stoermer, DP Fairlie, PR Young Journal of general virology 89 (4), 1010-1014, 2008 | 77 | 2008 |
| Site-directed mutagenesis and kinetic studies of the West Nile Virus NS3 protease identify key enzyme-substrate interactions KJ Chappell, TA Nall, MJ Stoermer, NX Fang, JDA Tyndall, DP Fairlie, ... Journal of Biological Chemistry 280 (4), 2896-2903, 2005 | 72 | 2005 |
| Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed TA Hill, RJ Lohman, HN Hoang, DS Nielsen, CCG Scully, WM Kok, L Liu, ... ACS medicinal chemistry letters 5 (10), 1148-1151, 2014 | 65 | 2014 |
| Structural Mimicry of Two Cytochrome b562 Interhelical Loops Using Macrocycles Constrained by Oxazoles and Thiazoles Y Singh, MJ Stoermer, AJ Lucke, T Guthrie, DP Fairlie Journal of the American Chemical Society 127 (18), 6563-6572, 2005 | 44 | 2005 |
| Current status of virtual screening as analysed by target class MJ Stoermer Medicinal Chemistry 2 (1), 89-112, 2006 | 42 | 2006 |
| Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists V Seow, J Lim, AJ Cotterell, MK Yau, W Xu, RJ Lohman, WM Kok, ... Scientific reports 6 (1), 24575, 2016 | 41 | 2016 |
| Downsizing a human inflammatory protein to a small molecule with equal potency and functionality RC Reid, MK Yau, R Singh, JK Hamidon, AN Reed, P Chu, JY Suen, ... Nature communications 4 (1), 2802, 2013 | 37 | 2013 |
| Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles Y Singh, MJ Stoermer, AJ Lucke, MP Glenn, DP Fairlie Organic Letters 4 (20), 3367-3370, 2002 | 32 | 2002 |
| Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3 KJ Chappell, MJ Stoermer, DP Fairlie, PR Young Protein expression and purification 53 (1), 87-96, 2007 | 31 | 2007 |
David P FairlieProfessor, University of QueenslandVerified email at imb.uq.edu.au
