Martin John Stoermer
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Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors
D Leung, K Schroder, H White, NX Fang, MJ Stoermer, G Abbenante, ...
Journal of Biological Chemistry 276 (49), 45762-45771, 2001
Orally absorbed cyclic peptides
DS Nielsen, NE Shepherd, W Xu, AJ Lucke, MJ Stoermer, DP Fairlie
Chemical reviews 117 (12), 8094-8128, 2017
Flavones are inhibitors of HIV-1 proteinase
RI Brinkworth, MJ Stoermer, DP Fairlie
Biochemical and biophysical research communications 188 (2), 631-637, 1992
Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria
KT Andrews, DP Fairlie, PK Madala, J Ray, DM Wyatt, PM Hilton, ...
Antimicrobial agents and chemotherapy 50 (2), 639-648, 2006
Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation
G Robin, K Chappell, MJ Stoermer, SH Hu, PR Young, DP Fairlie, ...
Journal of molecular biology 385 (5), 1568-1577, 2009
Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease
TA Nall, KJ Chappell, MJ Stoermer, NX Fang, JDA Tyndall, PR Young, ...
Journal of Biological Chemistry 279 (47), 48535-48542, 2004
Potent cyclic antagonists of the complement C5a receptor on human polymorphonuclear leukocytes. Relationships between structures and activity
DR March, LM Proctor, MJ Stoermer, R Sbaglia, G Abbenante, RC Reid, ...
Molecular pharmacology 65 (4), 868-879, 2004
In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses
T Kampmann, R Yennamalli, P Campbell, MJ Stoermer, DP Fairlie, ...
Antiviral research 84 (3), 234-241, 2009
West Nile Virus NS2B/NS3 protease as an antiviral target
KJ Chappell, MJ Stoermer, DP Fairlie, PR Young
Current medicinal chemistry 15 (27), 2771-2784, 2008
Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity
MJ Stoermer, KJ Chappell, S Liebscher, CM Jensen, CH Gan, PK Gupta, ...
Journal of medicinal chemistry 51 (18), 5714-5721, 2008
Insights to substrate binding and processing by West Nile Virus NS3 protease through combined modeling, protease mutagenesis, and kinetic studies
KJ Chappell, MJ Stoermer, DP Fairlie, PR Young
Journal of Biological Chemistry 281 (50), 38448-38458, 2006
Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity
KJ Chappell, MJ Stoermer, DP Fairlie, PR Young
Journal of general virology 89 (4), 1010-1014, 2008
Site-directed mutagenesis and kinetic studies of the West Nile Virus NS3 protease identify key enzyme-substrate interactions
KJ Chappell, TA Nall, MJ Stoermer, NX Fang, JDA Tyndall, DP Fairlie, ...
Journal of Biological Chemistry 280 (4), 2896-2903, 2005
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed
TA Hill, RJ Lohman, HN Hoang, DS Nielsen, CCG Scully, WM Kok, L Liu, ...
ACS medicinal chemistry letters 5 (10), 1148-1151, 2014
Structural Mimicry of Two Cytochrome b562 Interhelical Loops Using Macrocycles Constrained by Oxazoles and Thiazoles
Y Singh, MJ Stoermer, AJ Lucke, T Guthrie, DP Fairlie
Journal of the American Chemical Society 127 (18), 6563-6572, 2005
Current status of virtual screening as analysed by target class
MJ Stoermer
Medicinal Chemistry 2 (1), 89-112, 2006
Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists
V Seow, J Lim, AJ Cotterell, MK Yau, W Xu, RJ Lohman, WM Kok, ...
Scientific reports 6 (1), 24575, 2016
Downsizing a human inflammatory protein to a small molecule with equal potency and functionality
RC Reid, MK Yau, R Singh, JK Hamidon, AN Reed, P Chu, JY Suen, ...
Nature communications 4 (1), 2802, 2013
Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles
Y Singh, MJ Stoermer, AJ Lucke, MP Glenn, DP Fairlie
Organic Letters 4 (20), 3367-3370, 2002
Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3
KJ Chappell, MJ Stoermer, DP Fairlie, PR Young
Protein expression and purification 53 (1), 87-96, 2007
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