| The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2 AL Hsu, TT Ching, DS Wang, X Song, VM Rangnekar, CS Chen Journal of Biological Chemistry 275 (15), 11397-11403, 2000 | 911 | 2000 |
| Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation B Cadieux, TT Ching, SR VandenBerg, JF Costello Cancer research 66 (17), 8469-8476, 2006 | 288 | 2006 |
| HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity WC Chiang, TT Ching, HC Lee, C Mousigian, AL Hsu Cell 148 (1), 322-334, 2012 | 278 | 2012 |
| Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3 TT Ching, AK Maunakea, P Jun, C Hong, G Zardo, D Pinkel, DG Albertson, ... Nature genetics 37 (6), 645-651, 2005 | 181 | 2005 |
| Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact F Zhang, CC Tom, MC Kugler, TT Ching, JA Kreidberg, Y Wei, ... The Journal of cell biology 163 (1), 177-188, 2003 | 147 | 2003 |
| Phosphoinositide 3-kinase facilitates antigen-stimulated Ca2+ influx in RBL-2H3 mast cells via a phosphatidylinositol 3, 4, 5-trisphosphate-sensitive Ca2+ entry mechanism TT Ching, AL Hsu, AJ Johnson, CS Chen Journal of Biological Chemistry 276 (18), 14814-14820, 2001 | 95 | 2001 |
| Enhanced energy metabolism contributes to the extended life span of calorie-restricted Caenorhabditis elegans Y Yuan, CS Kadiyala, TT Ching, P Hakimi, S Saha, H Xu, C Yuan, ... Journal of Biological Chemistry 287 (37), 31414-31426, 2012 | 77 | 2012 |
| Novel function of phosphoinositide 3-kinase in T cell Ca2+ signaling: a phosphatidylinositol 3, 4, 5-trisphosphate-mediated Ca2+ entry mechanism AL Hsu, TT Ching, G Sen, DS Wang, S Bondada, KS Authi, CS Chen Journal of Biological Chemistry 275 (21), 16242-16250, 2000 | 71 | 2000 |
| Celecoxib extends C. elegans lifespan via inhibition of insulin‐like signaling but not cyclooxygenase‐2 activity TT Ching, WC Chiang, CS Chen, AL Hsu Aging cell 10 (3), 506-519, 2011 | 60 | 2011 |
| drr‐2 encodes an eIF4H that acts downstream of TOR in diet‐restriction‐induced longevity of C. elegans TT Ching, AB Paal, A Mehta, L Zhong, AL Hsu Aging cell 9 (4), 545-557, 2010 | 59 | 2010 |
| Integrin‐linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF‐1 C Kumsta, TT Ching, M Nishimura, AE Davis, S Gelino, HH Catan, X Yu, ... Aging cell 13 (3), 419-430, 2014 | 52 | 2014 |
| Reciprocal changes in phosphoenolpyruvate carboxykinase and pyruvate kinase with age are a determinant of aging in Caenorhabditis elegans Y Yuan, P Hakimi, C Kao, A Kao, R Liu, A Janocha, A Boyd-Tressler, ... Journal of Biological Chemistry 291 (3), 1307-1319, 2016 | 35 | 2016 |
| Specific binding of the C-terminal Src homology 2 domain of the p85α subunit of phosphoinositide 3-kinase to phosphatidylinositol 3, 4, 5-trisphosphate: localization and … TT Ching, HP Lin, CC Yang, M Oliveira, PJ Lu, CS Chen Journal of Biological Chemistry 276 (47), 43932-43938, 2001 | 29 | 2001 |
| Identification of multiple phosphoinositide-specific phospholipases D as new regulatory enzymes for phosphatidylinositol 3, 4, 5-trisphosphate TT Ching, DS Wang, AL Hsu, PJ Lu, CS Chen Journal of Biological Chemistry 274 (13), 8611-8617, 1999 | 29 | 1999 |
| AMPK-mediated formation of stress granules is required for dietary restriction-induced longevity in Caenorhabditis elegans TTC Chen-Ting Kuo, Guan-Ting You, Ying-Jie Jian, Ting-Shin Chen, Yu-Chen ... Aging cell 19 (6), e13157, 2020 | 28 | 2020 |
| HSB-1/HSF-1 pathway modulates histone H4 in mitochondria to control mtDNA transcription and longevity S Sural, CY Liang, FY Wang, TT Ching, AL Hsu Science Advances 6 (43), eaaz4452, 2020 | 24 | 2020 |
| Solid plate-based dietary restriction in Caenorhabditis elegans TT Ching, AL Hsu JoVE (Journal of Visualized Experiments), e2701, 2011 | 24 | 2011 |
| Biotinylated phosphatidylinositol 3, 4, 5-trisphosphate as affinity ligand DS Wang, TT Ching, JS Pyrek, CS Chen Analytical Biochemistry 280 (2), 301-307, 2000 | 19 | 2000 |
| High-throughput small molecule screening reveals Nrf2-dependent and-independent pathways of cellular stress resistance DB Lombard, WJ Kohler, AH Guo, C Gendron, M Han, W Ding, Y Lyu, ... Science advances 6 (40), eaaz7628, 2020 | 17 | 2020 |
| Oil Red O staining for lipid content in Caenorhabditis elegans FY Wang, TT Ching Bio-protocol 11 (16), e4124-e4124, 2021 | 16 | 2021 |
