Scott Canna
Scott Canna
Assistant Professor of Pediatrics and of Immunology
Verified email at
Cited by
Cited by
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition
R Goldbach-Mansky, NJ Dailey, SW Canna, A Gelabert, J Jones, BI Rubin, ...
New England Journal of Medicine 355 (6), 581-592, 2006
An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
SW Canna, AA de Jesus, S Gouni, SR Brooks, B Marrero, Y Liu, ...
Nature genetics 46 (10), 1140-1146, 2014
On the alert for cytokine storm: immunopathology in COVID‐19
LA Henderson, SW Canna, GS Schulert, S Volpi, PY Lee, KF Kernan, ...
Arthritis & Rheumatology 72 (7), 1059-1063, 2020
Repeated TLR9 stimulation results in macrophage activation syndrome–like disease in mice
EM Behrens, SW Canna, K Slade, S Rao, PA Kreiger, M Paessler, ...
The Journal of clinical investigation 121 (6), 2264-2277, 2011
Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling
AA de Jesus, SW Canna, Y Liu, R Goldbach-Mansky
Annual review of immunology 33, 823-874, 2015
Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition
SW Canna, C Girard, L Malle, A de Jesus, N Romberg, J Kelsen, ...
Journal of Allergy and Clinical Immunology 139 (5), 1698-1701, 2017
Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis
R Das, P Guan, L Sprague, K Verbist, P Tedrick, QA An, C Cheng, ...
Blood, The Journal of the American Society of Hematology 127 (13), 1666-1675, 2016
Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome
ES Weiss, C Girard-Guyonvarc’h, D Holzinger, AA de Jesus, Z Tariq, ...
Blood 131 (13), 1442-1455, 2018
Making sense of the cytokine storm: a conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes
SW Canna, EM Behrens
Pediatric Clinics 59 (2), 329-344, 2012
The NLRC 4 inflammasome
JA Duncan, SW Canna
Immunological reviews 281 (1), 115-123, 2018
Arthropathy of neonatal onset multisystem inflammatory disease (NOMID/CINCA)
SC Hill, M Namde, A Dwyer, A Poznanski, S Canna, R Goldbach-Mansky
Pediatric radiology 37 (2), 145-152, 2007
American College of Rheumatology Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 and …
LA Henderson, SW Canna, KG Friedman, M Gorelik, SK Lapidus, ...
A20 haploinsufficiency (HA20): clinical phenotypes and disease course of patients with a newly recognised NF-kB-mediated autoinflammatory disease
FA Aeschlimann, ED Batu, SW Canna, E Go, A Gül, P Hoffmann, ...
Annals of the rheumatic diseases 77 (5), 728-735, 2018
Interferon‐γ mediates anemia but is dispensable for fulminant Toll‐like receptor 9–induced macrophage activation syndrome and hemophagocytosis in mice
SW Canna, J Wrobel, N Chu, PA Kreiger, M Paessler, EM Behrens
Arthritis & Rheumatism 65 (7), 1764-1775, 2013
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever
F Moghaddas, R Llamas, D De Nardo, H Martinez-Banaclocha, ...
Annals of the rheumatic diseases 76 (12), 2085-2094, 2017
Not all hemophagocytes are created equally: appreciating the heterogeneity of the hemophagocytic syndromes
SW Canna, EM Behrens
Current opinion in rheumatology 24 (1), 113, 2012
NLRC4 inflammasomopathies
N Romberg, TP Vogel, SW Canna
Current opinion in allergy and clinical immunology 17 (6), 398, 2017
Emergent high fatality lung disease in systemic juvenile arthritis
VE Saper, G Chen, GH Deutsch, RP Guillerman, J Birgmeier, ...
Annals of the rheumatic diseases 78 (12), 1722-1731, 2019
New monogenic autoinflammatory diseases—a clinical overview
SW Canna, R Goldbach-Mansky
Seminars in immunopathology 37 (4), 387-394, 2015
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases
AA de Jesus, Y Hou, S Brooks, L Malle, A Biancotto, Y Huang, KR Calvo, ...
The Journal of clinical investigation 130 (4), 2020
The system can't perform the operation now. Try again later.
Articles 1–20