| Recon 2.2: from reconstruction to model of human metabolism N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ... Metabolomics 12, 1-7, 2016 | 308 | 2016 |
| A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... Cell systems 3 (5), 434-443. e8, 2016 | 238 | 2016 |
| Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption VS Martínez, S Dietmair, LE Quek, MP Hodson, P Gray, LK Nielsen Biotechnology and bioengineering 110 (2), 660-666, 2013 | 158 | 2013 |
| Reducing Recon 2 for steady-state flux analysis of HEK cell culture LE Quek, S Dietmair, M Hanscho, VS Martínez, N Borth, LK Nielsen Journal of biotechnology 184, 172-178, 2014 | 69 | 2014 |
| Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism VS Martínez, M Buchsteiner, P Gray, LK Nielsen, LE Quek Metabolic Engineering Communications 2, 46-57, 2015 | 62 | 2015 |
| Attenuating apoptosis in Chinese hamster ovary cells for improved biopharmaceutical production MN Henry, MA MacDonald, CA Orellana, PP Gray, M Gillard, K Baker, ... Biotechnology and Bioengineering 117 (4), 1187-1203, 2020 | 38 | 2020 |
| Network thermodynamic curation of human and yeast genome-scale metabolic models VS Martínez, LE Quek, LK Nielsen Biophysical journal 107 (2), 493-503, 2014 | 37 | 2014 |
| Viral vectors for the treatment of alcoholism: use of metabolic flux analysis for cell cultivation and vector production V Martinez, ZP Gerdtzen, BA Andrews, JA Asenjo Metabolic engineering 12 (2), 129-137, 2010 | 32 | 2010 |
| Toward Synthetic Biology Strategies for Adipic Acid Production: An in Silico Tool for Combined Thermodynamics and Stoichiometric Analysis of Metabolic Networks NJH Averesch, VS Martínez, LK Nielsen, JO Kromer ACS synthetic biology 7 (2), 490-509, 2018 | 27 | 2018 |
| Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications MA MacDonald, M Nöbel, D Roche Recinos, VS Martínez, BL Schulz, ... Critical reviews in biotechnology 42 (7), 1099-1115, 2022 | 22 | 2022 |
| Modeling apoptosis resistance in CHO cells with CRISPR‐mediated knockouts of Bak1, Bax, and Bok MA MacDonald, C Barry, T Groves, VS Martínez, PP Gray, K Baker, ... Biotechnology and Bioengineering 119 (6), 1380-1391, 2022 | 17 | 2022 |
| NExT: Integration of Thermodynamic Constraints and Metabolomics Data into a Metabolic Network VS Martínez, LK Nielsen Metabolic Flux Analysis: Methods and Protocols, 65-78, 2014 | 13 | 2014 |
| Engineering CHO cells galactose metabolism to reduce lactate synthesis N Jiménez, VS Martínez, ZP Gerdtzen Biotechnology letters 41, 779-788, 2019 | 9 | 2019 |
| ‘Omics driven discoveries of gene targets for apoptosis attenuation in CHO cells CA Orellana, VS Martínez, MA MacDonald, MN Henry, M Gillard, PP Gray, ... Biotechnology and Bioengineering 118 (1), 481-490, 2021 | 8 | 2021 |
| Engineering death resistance in CHO cells for improved perfusion culture MA MacDonald, M Nöbel, VS Martínez, K Baker, E Shave, PP Gray, ... MAbs 14 (1), 2083465, 2022 | 7 | 2022 |
| The topology of genome-scale metabolic reconstructions unravels independent modules and high network flexibility LKN Verónica S. Martínez, Pedro A. Saa, Jason Jooste, Kanupriya Tiwari, Lake ... PLOS Computational Biology 18 (6), e1010203, 2022 | 3 | 2022 |
| Quantification of microbial phenotypes VS Martínez, JO Krömer Metabolites 6 (4), 45, 2016 | 3 | 2016 |
| Amino acid degradation pathway inhibitory by‐products trigger apoptosis in CHO cells VS Martínez, K Rodriguez, T McCubbin, J Tong, S Mahler, E Shave, ... Biotechnology Journal 19 (2), 2300338, 2024 | | 2024 |
| Harnessing metabolic plasticity in CHO cells for enhanced perfusion cultivation M Nöbel, C Barry, MA MacDonald, K Baker, E Shave, S Mahler, T Munro, ... Biotechnology and Bioengineering, 2023 | | 2023 |
| Amino acid degradation pathway inhibitors trigger apoptosis in Chinese Hamster Ovary cells V Martinez, K Rodriguez, T McCubbin, J Tong, E Shave, S Mahler, ... | | 2023 |
Lars Keld NielsenProfessor of Biological Engineering, University of QueenslandVerified email at uq.edu.au
