Keith Kelley
Keith Kelley
Professor of Immunophysiology, University of Illinois at Urbana-Champaign
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From inflammation to sickness and depression: when the immune system subjugates the brain
R Dantzer, JC O'connor, GG Freund, RW Johnson, KW Kelley
Nature reviews neuroscience 9 (1), 46-56, 2008
Twenty years of research on cytokine-induced sickness behavior
R Dantzer, KW Kelley
Brain, behavior, and immunity 21 (2), 153-160, 2007
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2, 3-dioxygenase activation in mice
JC O'Connor, MA Lawson, C Andre, M Moreau, J Lestage, N Castanon, ...
Molecular psychiatry 14 (5), 511-522, 2009
Sickness behavior as a new target for drug development
S Kent, RM Bluthé, KW Kelley, R Dantzer
Trends in pharmacological sciences 13, 24-28, 1992
Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system
JP Godbout, J Chen, J Abraham, AF Richwine, BM Berg, KW Kelley, ...
The FASEB journal 19 (10), 1329-1331, 2005
Cytokine-induced sickness behavior
KW Kelley, RM Bluthé, R Dantzer, JH Zhou, WH Shen, RW Johnson, ...
Brain, behavior, and immunity 17 (1), 112-118, 2003
Inflammation-associated depression: from serotonin to kynurenine
R Dantzer, JC O’Connor, MA Lawson, KW Kelley
Psychoneuroendocrinology 36 (3), 426-436, 2011
Stress and immunity: an integrated view of relationships between the brain and the immune system
R Dantzer, KW Kelley
Life sciences 44 (26), 1995-2008, 1989
CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression
CL Raison, R Dantzer, KW Kelley, MA Lawson, BJ Woolwine, G Vogt, ...
Molecular psychiatry 15 (4), 393-403, 2010
Interferon-γ and tumor necrosis factor-α mediate the upregulation of indoleamine 2, 3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus …
JC O'Connor, C André, Y Wang, MA Lawson, SS Szegedi, J Lestage, ...
Journal of Neuroscience 29 (13), 4200-4209, 2009
Interleukin-10 in the brain
K Strle, JH Zhou, WH Shen, SR Broussard, RW Johnson, GG Freund, ...
Critical reviews in immunology 21 (5), 427-450, 2001
Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?
R Dantzer, JP Konsman, RM Bluthé, KW Kelley
Autonomic Neuroscience 85 (1-3), 60-65, 2000
Immune–neural connections: how the immune system’s response to infectious agents influences behavior
RH McCusker, KW Kelley
Journal of Experimental Biology 216 (1), 84-98, 2013
Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive …
F Frenois, M Moreau, J O’Connor, M Lawson, C Micon, J Lestage, ...
Psychoneuroendocrinology 32 (5), 516-531, 2007
Stress and immune function: a bibliographic review
KW Kelley
Annales de Recherches Veterinaires 11 (4), 445-478, 1980
Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism.
RM Bluthé, V Walter, P Parnet, S Laye, J Lestage, D Verrier, S Poole, ...
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 317 …, 1994
Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS
S Laye, RM Bluthe, S Kent, C Combe, C Medina, P Parnet, K Kelley, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 1995
NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice
AK Walker, DP Budac, S Bisulco, AW Lee, RA Smith, B Beenders, ...
Neuropsychopharmacology 38 (9), 1609-1616, 2013
Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1
S Jang, KW Kelley, RW Johnson
Proceedings of the National Academy of Sciences 105 (21), 7534-7539, 2008
Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1.
S Kent, RM Bluthe, R Dantzer, AJ Hardwick, KW Kelley, NJ Rothwell, ...
Proceedings of the National Academy of Sciences 89 (19), 9117-9120, 1992
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