| From inflammation to sickness and depression: when the immune system subjugates the brain R Dantzer, JC O'connor, GG Freund, RW Johnson, KW Kelley Nature reviews neuroscience 9 (1), 46-56, 2008 | 7681 | 2008 |
| Twenty years of research on cytokine-induced sickness behavior R Dantzer, KW Kelley Brain, behavior, and immunity 21 (2), 153-160, 2007 | 1668 | 2007 |
| Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2, 3-dioxygenase activation in mice JC O'Connor, MA Lawson, C Andre, M Moreau, J Lestage, N Castanon, ... Molecular psychiatry 14 (5), 511-522, 2009 | 1347 | 2009 |
| Sickness behavior as a new target for drug development S Kent, RM Bluthé, KW Kelley, R Dantzer Trends in pharmacological sciences 13, 24-28, 1992 | 1121 | 1992 |
| Exaggerated neuroinflammation and sickness behavior in aged mice after activation of the peripheral innate immune system JP Godbout, J Chen, J Abraham, AF Richwine, BM Berg, KW Kelley, ... The FASEB journal 19 (10), 1329-1331, 2005 | 997 | 2005 |
| Cytokine-induced sickness behavior KW Kelley, RM Bluthé, R Dantzer, JH Zhou, WH Shen, RW Johnson, ... Brain, behavior, and immunity 17 (1), 112-118, 2003 | 951 | 2003 |
| Inflammation-associated depression: from serotonin to kynurenine R Dantzer, JC O’Connor, MA Lawson, KW Kelley Psychoneuroendocrinology 36 (3), 426-436, 2011 | 806 | 2011 |
| Stress and immunity: an integrated view of relationships between the brain and the immune system R Dantzer, KW Kelley Life sciences 44 (26), 1995-2008, 1989 | 787 | 1989 |
| CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-α: relationship to CNS immune responses and depression CL Raison, R Dantzer, KW Kelley, MA Lawson, BJ Woolwine, G Vogt, ... Molecular psychiatry 15 (4), 393-403, 2010 | 690 | 2010 |
| Interferon-γ and tumor necrosis factor-α mediate the upregulation of indoleamine 2, 3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus … JC O'Connor, C André, Y Wang, MA Lawson, SS Szegedi, J Lestage, ... Journal of Neuroscience 29 (13), 4200-4209, 2009 | 580 | 2009 |
| Interleukin-10 in the brain K Strle, JH Zhou, WH Shen, SR Broussard, RW Johnson, GG Freund, ... Critical reviews in immunology 21 (5), 427-450, 2001 | 507 | 2001 |
| Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent? R Dantzer, JP Konsman, RM Bluthé, KW Kelley Autonomic Neuroscience 85 (1-3), 60-65, 2000 | 501 | 2000 |
| Immune–neural connections: how the immune system’s response to infectious agents influences behavior RH McCusker, KW Kelley Journal of Experimental Biology 216 (1), 84-98, 2013 | 484 | 2013 |
| Lipopolysaccharide induces delayed FosB/DeltaFosB immunostaining within the mouse extended amygdala, hippocampus and hypothalamus, that parallel the expression of depressive … F Frenois, M Moreau, J O’Connor, M Lawson, C Micon, J Lestage, ... Psychoneuroendocrinology 32 (5), 516-531, 2007 | 483 | 2007 |
| Stress and immune function: a bibliographic review KW Kelley Annales de Recherches Veterinaires 11 (4), 445-478, 1980 | 455 | 1980 |
| Lipopolysaccharide induces sickness behaviour in rats by a vagal mediated mechanism. RM Bluthé, V Walter, P Parnet, S Laye, J Lestage, D Verrier, S Poole, ... Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 317 …, 1994 | 449 | 1994 |
| Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS S Laye, RM Bluthe, S Kent, C Combe, C Medina, P Parnet, K Kelley, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 1995 | 441 | 1995 |
| NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice AK Walker, DP Budac, S Bisulco, AW Lee, RA Smith, B Beenders, ... Neuropsychopharmacology 38 (9), 1609-1616, 2013 | 424 | 2013 |
| Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1. S Kent, RM Bluthe, R Dantzer, AJ Hardwick, KW Kelley, NJ Rothwell, ... Proceedings of the National Academy of Sciences 89 (19), 9117-9120, 1992 | 405 | 1992 |
| Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1 S Jang, KW Kelley, RW Johnson Proceedings of the National Academy of Sciences 105 (21), 7534-7539, 2008 | 404 | 2008 |
