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Gilad Ofek
Gilad Ofek
Verified email at umd.edu
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Cited by
Cited by
Year
Distribution and three-dimensional structure of AIDS virus envelope spikes
P Zhu, J Liu, J Bess Jr, E Chertova, JD Lifson, H Grisé, GA Ofek, KA Taylor, ...
Nature 441 (7095), 847-852, 2006
10422006
Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
J Huang, G Ofek, L Laub, MK Louder, NA Doria-Rose, NS Longo, ...
Nature 491 (7424), 406-412, 2012
9722012
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
M Pancera, T Zhou, A Druz, IS Georgiev, C Soto, J Gorman, J Huang, ...
Nature 514 (7523), 455-461, 2014
8262014
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
G Ofek, M Tang, A Sambor, H Katinger, JR Mascola, R Wyatt, PD Kwong
Journal of virology 78 (19), 10724-10737, 2004
5892004
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ...
Nature structural & molecular biology 22 (7), 522-531, 2015
3652015
Elicitation of structure-specific antibodies by epitope scaffolds
G Ofek, FJ Guenaga, WR Schief, J Skinner, D Baker, R Wyatt, PD Kwong
Proceedings of the National Academy of Sciences 107 (42), 17880-17887, 2010
3462010
Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization
IS Georgiev, NA Doria-Rose, T Zhou, Y Do Kwon, RP Staupe, S Moquin, ...
Science 340 (6133), 751-756, 2013
2602013
Demonstration of rapid light-induced advances and delays of the human circadian clock using hormonal phase markers
E Van Cauter, J Sturis, MM Byrne, JD Blackman, R Leproult, G Ofek, ...
American Journal of Physiology-Endocrinology and Metabolism 266 (6), E953-E963, 1994
2031994
Mining the antibodyome for HIV-1–neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains
J Zhu, G Ofek, Y Yang, B Zhang, MK Louder, G Lu, K McKee, M Pancera, ...
Proceedings of the National Academy of Sciences 110 (16), 6470-6475, 2013
1592013
Potent and broad HIV-neutralizing antibodies in memory B cells and plasma
LTD Williams, G Ofek, S Schätzle, JR McDaniel, X Lu, NI Nicely, L Wu, ...
Science immunology 2 (7), eaal2200, 2017
1372017
Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region
G Ofek, K McKee, Y Yang, ZY Yang, J Skinner, FJ Guenaga, R Wyatt, ...
Journal of virology 84 (6), 2955-2962, 2010
1372010
Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies
Z Zhu, HR Qin, W Chen, Q Zhao, X Shen, R Schutte, Y Wang, G Ofek, ...
Journal of virology 85 (21), 11401-11408, 2011
1282011
Heterologous Epitope-Scaffold Prime∶ Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
J Guenaga, P Dosenovic, G Ofek, D Baker, WR Schief, PD Kwong, ...
PloS one 6 (1), e16074, 2011
1072011
Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline
IS Georgiev, RS Rudicell, KO Saunders, W Shi, T Kirys, K McKee, ...
The Journal of Immunology 192 (3), 1100-1106, 2014
1052014
Enhancing protein crystallization through precipitant synergy
S Majeed, G Ofek, A Belachew, C Huang, T Zhou, PD Kwong
Structure 11 (9), 1061-1070, 2003
992003
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization
M Kim, ZYJ Sun, KD Rand, X Shi, L Song, Y Cheng, AF Fahmy, ...
Nature structural & molecular biology 18 (11), 1235-1243, 2011
982011
Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41
SM Dennison, LL Sutherland, FH Jaeger, KM Anasti, R Parks, S Stewart, ...
PloS one 6 (11), e27824, 2011
942011
Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies
GH Bird, A Irimia, G Ofek, PD Kwong, IA Wilson, LD Walensky
Nature structural & molecular biology 21 (12), 1058-1067, 2014
882014
Optimization of the solubility of HIV-1-neutralizing antibody 10E8 through somatic variation and structure-based design
YD Kwon, IS Georgiev, G Ofek, B Zhang, M Asokan, RT Bailer, A Bao, ...
Journal of virology 90 (13), 5899-5914, 2016
772016
Somatic populations of PGT135–137 HIV-1-neutralizing antibodies identified by 454 pyrosequencing and bioinformatics
J Zhu, S O’Dell, G Ofek, M Pancera, X Wu, B Zhang, Z Zhang, ...
Frontiers in microbiology 3, 315, 2012
732012
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