Ross Hannan
Ross Hannan
Professor Ross Hannan, Centenary Chair of Cancer Research, Associate Dean of Research
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mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar …
KM Hannan, Y Brandenburger, A Jenkins, K Sharkey, A Cavanaugh, ...
Molecular and cellular biology 23 (23), 8862-8877, 2003
Targeting RNA Polymerase I with an Oral Small Molecule CX-5461 Inhibits Ribosomal RNA Synthesis and Solid Tumor GrowthSelective Inhibitor of RNA Pol I Complex Exhibits …
D Drygin, A Lin, J Bliesath, CB Ho, SE O'Brien, C Proffitt, M Omori, ...
Cancer research 71 (4), 1418-1430, 2011
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53
MJ Bywater, G Poortinga, E Sanij, N Hein, A Peck, C Cullinane, M Wall, ...
Cancer cell 22 (1), 51-65, 2012
The renin–angiotensin system and cancer: old dog, new tricks
AJ George, WG Thomas, RD Hannan
Nature Reviews Cancer 10 (11), 745-759, 2010
ATRX interacts with H3. 3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
LH Wong, JD McGhie, M Sim, MA Anderson, S Ahn, RD Hannan, ...
Genome research 20 (3), 351-360, 2010
Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere
LH Wong, KH Brettingham-Moore, L Chan, JM Quach, MA Anderson, ...
Genome research 17 (8), 1146-1160, 2007
Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function
K Jastrzebski, KM Hannan, EB Tchoubrieva, RD Hannan, RB Pearson
Growth factors 25 (4), 209-226, 2007
Direct actions of urotensin II on the heart: implications for cardiac fibrosis and hypertrophy
A Tzanidis, RD Hannan, WG Thomas, D Onan, DJ Autelitano, F See, ...
Circulation research 93 (3), 246-253, 2003
An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF
VY Stefanovsky, G Pelletier, R Hannan, T Gagnon-Kugler, LI Rothblum, ...
Molecular cell 8 (5), 1063-1073, 2001
Cardiac hypertrophy: a matter of translation
RD Hannan, A Jenkins, AK Jenkins, Y Brandenburger
Clinical and Experimental Pharmacology and Physiology 30 (8), 517-527, 2003
AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy
MV Astle, KM Hannan, PY Ng, RS Lee, AJ George, AK Hsu, Y Haupt, ...
Oncogene 31 (15), 1949-1962, 2012
Targeting the nucleolus for cancer intervention
JE Quin, JR Devlin, D Cameron, KM Hannan, RB Pearson, RD Hannan
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (6), 802-816, 2014
Adenoviral-directed expression of the type 1A angiotensin receptor promotes cardiomyocyte hypertrophy via transactivation of the epidermal growth factor receptor
WG Thomas, Y Brandenburger, DJ Autelitano, T Pham, H Qian, ...
Circulation research 90 (2), 135-142, 2002
The nucleolus: an emerging target for cancer therapy
N Hein, KM Hannan, AJ George, E Sanij, RD Hannan
Trends in molecular medicine 19 (11), 643-654, 2013
UBF levels determine the number of active ribosomal RNA genes in mammals
E Sanij, G Poortinga, K Sharkey, S Hung, TP Holloway, J Quin, E Robb, ...
The Journal of cell biology 183 (7), 1259-1274, 2008
MAD1 and c‐MYC regulate UBF and rDNA transcription during granulocyte differentiation
G Poortinga, KM Hannan, H Snelling, CR Walkley, A Jenkins, K Sharkey, ...
The EMBO journal 23 (16), 3325-3335, 2004
Dysregulation of the basal RNA polymerase transcription apparatus in cancer
MJ Bywater, RB Pearson, GA McArthur, RD Hannan
Nature Reviews Cancer 13 (5), 299-314, 2013
Nucleologenesis: U3 snRNA-containing prenucleolar bodies move to sites of active pre-rRNA transcription after mitosis.
LF Jimenez-Garcia, ML Segura-Valdez, RL Ochs, LI Rothblum, R Hannan, ...
Molecular biology of the cell 5 (9), 955-966, 1994
Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1
KM Hannan, RD Hannan, SD Smith, LS Jefferson, M Lun, LI Rothblum
Oncogene 19 (43), 4988-4999, 2000
A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling
YC Chen, AV Bui, J Diesch, R Manasseh, C Hausding, J Rivera, I Haviv, ...
Circulation research 113 (3), 252-265, 2013
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