Kyren Lazarus
Kyren Lazarus
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Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter
NI Fleming, KC Knower, KA Lazarus, PJ Fuller, ER Simpson, CD Clyne
PloS one 5 (12), e14389, 2010
Kupffer cell–monocyte communication is essential for initiating murine liver progenitor cell–mediated liver regeneration
CL Elsegood, CW Chan, MA Degli‐Esposti, ME Wikstrom, A Domenichini, ...
Hepatology 62 (4), 1272-1284, 2015
Therapeutic potential of liver receptor homolog-1 modulators
KA Lazarus, D Wijayakumara, AL Chand, ER Simpson, CD Clyne
The Journal of steroid biochemistry and molecular biology 130 (3-5), 138-146, 2012
The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation
AL Chand, DD Wijayakumara, KC Knower, KA Herridge, TL Howard, ...
PloS one 7 (2), e31593, 2012
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma
R Coulson, SH Liew, AA Connelly, NS Yee, S Deb, B Kumar, AC Vargas, ...
Oncotarget 8 (12), 18640, 2017
BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
KA Lazarus, F Hadi, E Zambon, K Bach, MF Santolla, JK Watson, ...
Nature communications 9 (1), 1-11, 2018
Estradiol regulates Tumor Necrosis Factor-α expression and secretion in Estrogen Receptor positive breast cancer cells
SQ To, V Cheung, KA Lazarus, KC Knower, CD Clyne
Molecular and cellular endocrinology 394 (1-2), 21-28, 2014
Transformation of naked mole-rat cells
F Hadi, Y Kulaberoglu, KA Lazarus, K Bach, R Ugur, P Beattie, ESJ Smith, ...
Nature 583 (7814), E1-E7, 2020
Liver receptor homologue-1 expression in ovarian epithelial and granulosa cell tumours
AL Chand, N Pathirage, K Lazarus, S Chu, AE Drummond, PJ Fuller, ...
Steroids 78 (7), 700-706, 2013
Conditional overexpression of liver receptor homolog-1 in female mouse mammary epithelium results in altered mammary morphogenesis via the induction of TGF-β
KA Lazarus, KA Brown, MJ Young, Z Zhao, RS Coulson, AL Chand, ...
Endocrinology 155 (5), 1606-1617, 2014
Oestradiol reduces liver receptor homolog-1 mRNA transcript stability in breast cancer cell lines
KA Lazarus, Z Zhao, KC Knower, SQ To, AL Chand, CD Clyne
Biochemical and biophysical research communications 438 (3), 533-539, 2013
The angiotensin receptor blocker, losartan, inhibits mammary tumor development and progression to invasive carcinoma. Oncotarget. 2017; 8 (12): 18640-56
R Coulson, SH Liew, AA Connelly, NS Yee, S Deb, B Kumar, AC Vargas, ...
Cell-intrinsic differences between human airway epithelial cells from children and adults
EF Maughan, E Nigro, A Pennycuick, KHC Gowers, C Denais, ...
bioRxiv, 2020
Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors
K Bach, S Pensa, M Zarocsinceva, K Kania, J Stockis, S Pinaud, ...
Nature communications 12 (1), 1-11, 2021
Naked Mole-Rat Cells are Susceptible to Malignant Transformation by SV40LT and Oncogenic Ras
F Hadi, Y Kulaberoglu, KA Lazarus, P Beattie, ESJ Smith, WT Khaled
BioRxiv, 404574, 2018
Lung1. 6
KA Lazarus, A Pennycuick, RE Hynds, SM Janes
Lung Stem Cells in Development, Health and Disease 91, 340, 2021
PO-086 BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous cell carcinoma
K Lazarus, F Hadi, K Bach, J Watson, M Das, G Ladds, J Le Quesne, ...
ESMO Open 3, A54-A55, 2018
Bcl11a Marks Mammary Progenitor Cells and Promotes Early Cellular Changes Associated with TNBC by Recruiting Chd8
S Pensa, KA Lazarus, K Bach, MF Santolla, M Maggiolini, J Cassidy, ...
Available at SSRN 3224558, 2018
Abstract PR01: Understanding the role of BCL11A in triple-negative breast cancer
K Lazarus, C Caldas, P Liu, WT Khaled
Molecular Cancer Research 14 (2 Supplement), PR01-PR01, 2016
Liver receptor homologue-1 increases incidence of DMBA-induced mammary tumors
KA Lazarus, K Brown, M Young, J Cain, S Jayasekara, R Coulson, ...
Cancer Research 74 (19 Supplement), 76-76, 2014
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