Aromatase is a direct target of FOXL2: C134W in granulosa cell tumors via a single highly conserved binding site in the ovarian specific promoter NI Fleming, KC Knower, KA Lazarus, PJ Fuller, ER Simpson, CD Clyne PloS one 5 (12), e14389, 2010 | 144 | 2010 |
Kupffer cell–monocyte communication is essential for initiating murine liver progenitor cell–mediated liver regeneration CL Elsegood, CW Chan, MA Degli‐Esposti, ME Wikstrom, A Domenichini, ... Hepatology 62 (4), 1272-1284, 2015 | 90 | 2015 |
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma R Coulson, SH Liew, AA Connelly, NS Yee, S Deb, B Kumar, AC Vargas, ... Oncotarget 8 (12), 18640, 2017 | 76 | 2017 |
The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation AL Chand, DD Wijayakumara, KC Knower, KA Herridge, TL Howard, ... PloS one 7 (2), e31593, 2012 | 71 | 2012 |
Therapeutic potential of liver receptor homolog-1 modulators KA Lazarus, D Wijayakumara, AL Chand, ER Simpson, CD Clyne The Journal of steroid biochemistry and molecular biology 130 (3-5), 138-146, 2012 | 66 | 2012 |
BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma KA Lazarus, F Hadi, E Zambon, K Bach, MF Santolla, JK Watson, ... Nature communications 9 (1), 3327, 2018 | 62 | 2018 |
Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors K Bach, S Pensa, M Zarocsinceva, K Kania, J Stockis, S Pinaud, ... Nature Communications 12 (1), 1502, 2021 | 42 | 2021 |
Transformation of naked mole-rat cells F Hadi, Y Kulaberoglu, KA Lazarus, K Bach, R Ugur, P Beattie, ESJ Smith, ... Nature 583 (7814), E1-E7, 2020 | 37 | 2020 |
Estradiol regulates Tumor Necrosis Factor-α expression and secretion in Estrogen Receptor positive breast cancer cells SQ To, V Cheung, KA Lazarus, KC Knower, CD Clyne Molecular and cellular endocrinology 394 (1-2), 21-28, 2014 | 22 | 2014 |
Liver receptor homologue-1 expression in ovarian epithelial and granulosa cell tumours AL Chand, N Pathirage, K Lazarus, S Chu, AE Drummond, PJ Fuller, ... Steroids 78 (7), 700-706, 2013 | 16 | 2013 |
Cell-intrinsic differences between human airway epithelial cells from children and adults EF Maughan, RE Hynds, A Pennycuick, E Nigro, KHC Gowers, C Denais, ... Iscience 25 (11), 2022 | 13 | 2022 |
Conditional overexpression of liver receptor homolog-1 in female mouse mammary epithelium results in altered mammary morphogenesis via the induction of TGF-β KA Lazarus, KA Brown, MJ Young, Z Zhao, RS Coulson, AL Chand, ... Endocrinology 155 (5), 1606-1617, 2014 | 13 | 2014 |
Oestradiol reduces liver receptor homolog-1 mRNA transcript stability in breast cancer cell lines KA Lazarus, Z Zhao, KC Knower, SQ To, AL Chand, CD Clyne Biochemical and biophysical research communications 438 (3), 533-539, 2013 | 11 | 2013 |
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma. Oncotarget. 2017; 8: 18640–18656 R Coulson, SH Liew, AA Connelly, NS Yee, S Deb, B Kumar, AC Vargas, ... | 9 | |
Naked Mole-Rat Cells are Susceptible to Malignant Transformation by SV40LT and Oncogenic Ras F Hadi, Y Kulaberoglu, KA Lazarus, P Beattie, ESJ Smith, WT Khaled BioRxiv, 404574, 2018 | 1 | 2018 |
BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous cell carcinoma KA Lazarus, F Hadi, E Zambon, K Bach, MF Santolla, JK Watson, ... bioRxiv, 223776, 2017 | 1 | 2017 |
Origins and Actions of TNF-Alpha in the Breast Tumor Microenvironment: A Novel Model of Targeted Inhibition through Endocrine Therapy KC Knower, SQG To, V Cheung, KA Lazarus, CD Clyne ENDOCRINE REVIEWS 35 (3), 2014 | 1 | 2014 |
A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence JC Orr, A Laali, PF Durrenberger, KA Lazarus, MB El Mdawar, SM Janes, ... bioRxiv, 2024.02. 09.579635, 2024 | | 2024 |
Power of Transcriptomics in Lung Biology E Mdawar, P Marie-Belle, L Adam, A Kyren Encyclopedia of Respiratory Medicine (Second Edition), 763-772, 2022 | | 2022 |
Lung1. 6 KA Lazarus, A Pennycuick, RE Hynds, SM Janes Lung Stem Cells in Development, Health and Disease 91, 340, 2021 | | 2021 |