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Joshua M Hardy
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A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses
AA Amarilla, JDJ Sng, R Parry, JM Deerain, JR Potter, YX Setoh, ...
Nature Communications 12 (1), 3431, 2021
902021
Structural insights into the assembly and regulation of distinct viral capsid complexes
S Sarker, MC Terrón, Y Khandokar, D Aragao, JM Hardy, M Radjainia, ...
Nature communications 7 (1), 13014, 2016
512016
A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses
JM Hardy, ND Newton, N Modhiran, CAP Scott, H Venugopal, LJ Vet, ...
Nature Communications 12 (1), 3266, 2021
362021
The architecture and stabilisation of flagellotropic tailed bacteriophages
JM Hardy, RA Dunstan, R Grinter, MJ Belousoff, J Wang, D Pickard, ...
Nature communications 11 (1), 3748, 2020
342020
The structure of an infectious immature flavivirus redefines viral architecture and maturation
ND Newton, JM Hardy, N Modhiran, LE Hugo, AA Amarilla, S Bibby, ...
Science Advances 7 (20), eabe4507, 2021
332021
The flagellotropic bacteriophage YSD1 targets Salmonella Typhi with a Chi‐like protein tail fibre
RA Dunstan, D Pickard, S Dougan, D Goulding, C Cormie, J Hardy, F Li, ...
Molecular microbiology 112 (6), 1831-1846, 2019
292019
Escape of hepatitis C virus from epitope I neutralization increases sensitivity of other neutralization epitopes
J Gu, J Hardy, I Boo, P Vietheer, K McCaffrey, Y Alhammad, A Chopra, ...
Journal of Virology 92 (9), 10.1128/jvi. 02066-17, 2018
252018
Tall tails: cryo-electron microscopy of phage tail DNA ejection conduits
JM Hardy, RA Dunstan, T Lithgow, F Coulibaly
Biochemical Society Transactions 50 (1), 459-22W, 2022
162022
Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1
O Patel, MJ Roy, A Kropp, JM Hardy, W Dai, IS Lucet
Communications Biology 4 (1), 1105, 2021
162021
Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host-restriction
AMG Colmant, CA O'Brien, ND Newton, D Watterson, J Hardy, F Coulibaly, ...
Journal of General Virology 101 (4), 440-452, 2020
152020
Virus-like particles containing the E2 Core domain of hepatitis C virus generate broadly neutralizing antibodies in Guinea pigs
J McGregor, JM Hardy, CS Lay, I Boo, M Piontek, M Suckow, F Coulibaly, ...
Journal of virology 96 (5), e01675-21, 2022
82022
Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling
MJ Roy, MG Surudoi, A Kropp, J Hou, W Dai, JM Hardy, LY Liang, ...
Nature Communications 14 (1), 3542, 2023
42023
Production and purification of the PEAK pseudokinases for structural and functional studies
O Patel, M Surudoi, W Dai, JM Hardy, MJ Roy, IS Lucet
Methods in enzymology 667, 1-35, 2022
42022
Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin
KTG Sarson-Lawrence, JM Hardy, J Iaria, D Stockwell, K Behrens, ...
Nature Communications 15 (1), 1135, 2024
2024
Structure-Guided Prediction of the Functional Impact of DCLK1 Mutations on Tumorigenesis
ALE Carli, JM Hardy, H Hoblos, M Ernst, IS Lucet, M Buchert
Biomedicines 11 (3), 990, 2023
2023
When two’sa crowd-Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3/Crk signaling
MJ Roy, MG Surudoi, A Kropp, J Hou, W Dai, JM Hardy, LY Liang, ...
bioRxiv, 2022.09. 01.506260, 2022
2022
When two’sa crowd-Structural mapping of PEAK pseudokinase interactions identifies 14 3 3 as a molecular switch for PEAK3/Crk signaling.
I Lucet, M Roy, M Surudoi, A Kropp, J Hou, W Dai, J Hardy, LY Liang, ...
2022
The architecture of viruses: Structures of a key epitope of HCV, a flagellotropic bacteriophage, and the baculovirus nucleocapsid
J HARDY
Monash University, 0
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Articles 1–18