| Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms HR Wardill, RJ Gibson, YZA Van Sebille, KR Secombe, JK Coller, ... Molecular cancer therapeutics 15 (6), 1376-1386, 2016 | 142 | 2016 |
| The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy‐induced gastrointestinal toxicity KR Secombe, JK Coller, RJ Gibson, HR Wardill, JM Bowen International journal of cancer 144 (10), 2365-2376, 2019 | 62 | 2019 |
| Adjunctive fecal microbiota transplantation in supportive oncology: Emerging indications and considerations in immunocompromised patients HR Wardill, KR Secombe, RV Bryant, MD Hazenberg, SP Costello EBioMedicine 44, 730-740, 2019 | 58 | 2019 |
| TLR4-dependent claudin-1 internalization and secretagogue-mediated chloride secretion regulate irinotecan-induced diarrhea HR Wardill, JM Bowen, YZA Van Sebille, KR Secombe, JK Coller, IA Ball, ... Molecular Cancer Therapeutics 15 (11), 2767-2779, 2016 | 46 | 2016 |
| Diarrhea induced by small molecule tyrosine kinase inhibitors compared with chemotherapy: potential role of the microbiome KR Secombe, YZA Van Sebille, BJ Mayo, JK Coller, RJ Gibson, ... Integrative Cancer Therapies 19, 1534735420928493, 2020 | 44 | 2020 |
| Guidelines for reporting on animal fecal transplantation (GRAFT) studies: recommendations from a systematic review of murine transplantation protocols KR Secombe, GH Al-Qadami, CB Subramaniam, JM Bowen, J Scott, ... Gut Microbes 13 (1), 1979878, 2021 | 38 | 2021 |
| Gut microbiota-derived short-chain fatty acids: impact on cancer treatment response and toxicities GH Al-Qadami, KR Secombe, CB Subramaniam, HR Wardill, JM Bowen Microorganisms 10 (10), 2048, 2022 | 33 | 2022 |
| Dacomitinib‐induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats YZA Van Sebille, RJ Gibson, HR Wardill, KR Secombe, IA Ball, ... International journal of cancer 140 (12), 2820-2829, 2017 | 33 | 2017 |
| Targeting neratinib-induced diarrhea with budesonide and colesevelam in a rat model KR Secombe, IA Ball, J Shirren, AD Wignall, J Finnie, D Keefe, ... Cancer chemotherapy and pharmacology 83, 531-543, 2019 | 20 | 2019 |
| The GLP-2 analogue elsiglutide reduces diarrhoea caused by the tyrosine kinase inhibitor lapatinib in rats BJ Mayo, KR Secombe, AD Wignall, E Bateman, D Thorpe, C Pietra, ... Cancer chemotherapy and pharmacology 85, 793-803, 2020 | 16 | 2020 |
| Baseline gut microbiota composition is associated with oral mucositis and tumour recurrence in patients with head and neck cancer: A pilot study G Al-Qadami, J Bowen, Y Van Sebille, K Secombe, M Dorraki, J Verjans, ... Supportive Care in Cancer 31 (1), 98, 2023 | 15 | 2023 |
| Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report JK Coller, JM Bowen, IA Ball, HR Wardill, YZA van Sebille, ... Cancer chemotherapy and pharmacology 79, 431-434, 2017 | 14 | 2017 |
| A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options HR Wardill, RJ Gibson, YZA Van Sebille, KR Secombe, RM Logan, ... Experimental Biology and Medicine 241 (13), 1386-1394, 2016 | 11 | 2016 |
| Antibiotic treatment targeting gram negative bacteria prevents neratinib-induced diarrhea in rats KR Secombe, IA Ball, AD Wignall, E Bateman, DM Keefe, JM Bowen Neoplasia 30, 100806, 2022 | 7 | 2022 |
| Pathophysiology of neratinib-induced diarrhea in male and female rats: microbial alterations a potential determinant KR Secombe, IA Ball, J Shirren, AD Wignall, DM Keefe, JM Bowen Breast Cancer 28, 99-109, 2021 | 6 | 2021 |
| Intestinal toll-like receptor 4 knockout alters the functional capacity of the gut microbiome following irinotecan treatment KR Secombe, EE Crame, JSY Tam, HR Wardill, RJ Gibson, JK Coller, ... Cancer chemotherapy and pharmacology, 1-7, 2022 | 4 | 2022 |
| Epithelial-specific TLR4 knockout challenges current evidence of tlr4 homeostatic control of gut permeability EE Crame, JM Bowen, KR Secombe, JK Coller, M François, W Leifert, ... Inflammatory Intestinal Diseases 6 (4), 199-209, 2021 | 4 | 2021 |
| Pre-treatment Blautia abundance regulates chemotherapy-induced gastrointestinal toxicity risk: a pilot study K Secombe, J Bowen, J Coller, R Gibson, A Stringer, N Al-Dasooqi, ... ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 14, 59-59, 2018 | 3 | 2018 |
| Budesonide reduces neratinib-induced gastrointestinal injury and diarrhoea in rats KR Secombe, IA Ball, J Shirren, AD Wignall, HR Wardill, YZA Van Sebille, ... ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 13, 74-74, 2017 | 3 | 2017 |
| Advanced statistics identification of participant and treatment predictors associated with severe adverse effects induced by fluoropyrimidine-based chemotherapy SK Korver, JM Bowen, RJ Gibson, IA Ball, KR Secombe, TJ Wain, ... Cancer Chemotherapy and Pharmacology 91 (6), 507-521, 2023 | 1 | 2023 |
