Follow
Kate Secombe
Kate Secombe
Postdoctoral Research Fellow, University of Queensland
Verified email at uq.edu.au - Homepage
Title
Cited by
Cited by
Year
Irinotecan-Induced Gastrointestinal Dysfunction and Pain Are Mediated by Common TLR4-Dependent MechanismsTLR4 and Chemotherapy-Induced Toxicity
HR Wardill, RJ Gibson, YZA Van Sebille, KR Secombe, JK Coller, ...
Molecular cancer therapeutics 15 (6), 1376-1386, 2016
1022016
Adjunctive fecal microbiota transplantation in supportive oncology: Emerging indications and considerations in immunocompromised patients
HR Wardill, KR Secombe, RV Bryant, MD Hazenberg, SP Costello
EBioMedicine 44, 730-740, 2019
422019
TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced DiarrheaTLR4-Dependent Tight Junction Regulation
HR Wardill, JM Bowen, YZA Van Sebille, KR Secombe, JK Coller, IA Ball, ...
Molecular Cancer Therapeutics 15 (11), 2767-2779, 2016
352016
The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy‐induced gastrointestinal toxicity
KR Secombe, JK Coller, RJ Gibson, HR Wardill, JM Bowen
International journal of cancer 144 (10), 2365-2376, 2019
302019
Dacomitinib‐induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats
YZA Van Sebille, RJ Gibson, HR Wardill, KR Secombe, IA Ball, ...
International Journal of Cancer 140 (12), 2820-2829, 2017
222017
Diarrhea induced by small molecule tyrosine kinase inhibitors compared with chemotherapy: potential role of the microbiome
KR Secombe, YZA Van Sebille, BJ Mayo, JK Coller, RJ Gibson, ...
Integrative Cancer Therapies 19, 1534735420928493, 2020
182020
Targeting neratinib-induced diarrhea with budesonide and colesevelam in a rat model
KR Secombe, IA Ball, J Shirren, AD Wignall, J Finnie, D Keefe, ...
Cancer chemotherapy and pharmacology 83 (3), 531-543, 2019
142019
Guidelines for reporting on animal fecal transplantation (GRAFT) studies: recommendations from a systematic review of murine transplantation protocols
KR Secombe, GH Al-Qadami, CB Subramaniam, JM Bowen, J Scott, ...
Gut microbes 13 (1), 1979878, 2021
112021
Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report
JK Coller, JM Bowen, IA Ball, HR Wardill, YZA van Sebille, ...
Cancer chemotherapy and pharmacology 79 (2), 431-434, 2017
92017
A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options
HR Wardill, RJ Gibson, YZA Van Sebille, KR Secombe, RM Logan, ...
Experimental Biology and Medicine 241 (13), 1386-1394, 2016
92016
The GLP-2 analogue elsiglutide reduces diarrhoea caused by the tyrosine kinase inhibitor lapatinib in rats
BJ Mayo, KR Secombe, AD Wignall, E Bateman, D Thorpe, C Pietra, ...
Cancer chemotherapy and pharmacology 85 (4), 793-803, 2020
82020
Budesonide reduces neratinib-induced gastrointestinal injury and diarrhoea in rats
KR Secombe, IA Ball, J Shirren, AD Wignall, HR Wardill, YZA Van Sebille, ...
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 13, 74-74, 2017
32017
Pathophysiology of neratinib-induced diarrhea in male and female rats: microbial alterations a potential determinant
KR Secombe, IA Ball, J Shirren, AD Wignall, DM Keefe, JM Bowen
Breast Cancer 28 (1), 99-109, 2021
22021
Pre-treatment Blautia abundance regulates chemotherapy-induced gastrointestinal toxicity risk: a pilot study
K Secombe, J Bowen, J Coller, R Gibson, A Stringer, N Al-Dasooqi, ...
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 14, 59-59, 2018
22018
Epithelial-specific TLR4 knockout challenges current evidence of TLR4 homeostatic control of gut permeability
EE Crame, JM Bowen, KR Secombe, JK Coller, M François, W Leifert, ...
Inflammatory Intestinal Diseases 6 (4), 199-209, 2021
12021
Baseline gut microbiota composition is associated with oral mucositis and tumour recurrence in patients with head and neck cancer: a pilot study
G Al-Qadami, J Bowen, Y Van Sebille, K Secombe, M Dorraki, J Verjans, ...
2022
Antibiotic treatment targeting gram negative bacteria prevents neratinib-induced diarrhea in rats
KR Secombe, IA Ball, AD Wignall, E Bateman, DM Keefe, JM Bowen
Neoplasia 30, 100806, 2022
2022
Intestinal toll-like receptor 4 knockout alters the functional capacity of the gut microbiome following irinotecan treatment
KR Secombe, EE Crame, JSY Tam, HR Wardill, RJ Gibson, JK Coller, ...
Cancer Chemotherapy and Pharmacology 89 (2), 275-281, 2022
2022
Using patient-reported outcome measures to determine the role of the microbiome in cancer treatment-induced diarrhoea
K Secombe, I Ball, C Subramaniam, G Al-Qadami, J Bowen, HR Wardill
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 17, 174-175, 2021
2021
200| Intestinal epithelial TLR4 are crucial to chemotherapy toxicity development
E Crame, HR Wardill, K Secombe, J Coller, J Bowen
2021
The system can't perform the operation now. Try again later.
Articles 1–20