| Irinotecan-Induced Gastrointestinal Dysfunction and Pain Are Mediated by Common TLR4-Dependent MechanismsTLR4 and Chemotherapy-Induced Toxicity HR Wardill, RJ Gibson, YZA Van Sebille, KR Secombe, JK Coller, ... Molecular cancer therapeutics 15 (6), 1376-1386, 2016 | 102 | 2016 |
| Adjunctive fecal microbiota transplantation in supportive oncology: Emerging indications and considerations in immunocompromised patients HR Wardill, KR Secombe, RV Bryant, MD Hazenberg, SP Costello EBioMedicine 44, 730-740, 2019 | 42 | 2019 |
| TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced DiarrheaTLR4-Dependent Tight Junction Regulation HR Wardill, JM Bowen, YZA Van Sebille, KR Secombe, JK Coller, IA Ball, ... Molecular Cancer Therapeutics 15 (11), 2767-2779, 2016 | 35 | 2016 |
| The bidirectional interaction of the gut microbiome and the innate immune system: Implications for chemotherapy‐induced gastrointestinal toxicity KR Secombe, JK Coller, RJ Gibson, HR Wardill, JM Bowen International journal of cancer 144 (10), 2365-2376, 2019 | 30 | 2019 |
| Dacomitinib‐induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats YZA Van Sebille, RJ Gibson, HR Wardill, KR Secombe, IA Ball, ... International Journal of Cancer 140 (12), 2820-2829, 2017 | 22 | 2017 |
| Diarrhea induced by small molecule tyrosine kinase inhibitors compared with chemotherapy: potential role of the microbiome KR Secombe, YZA Van Sebille, BJ Mayo, JK Coller, RJ Gibson, ... Integrative Cancer Therapies 19, 1534735420928493, 2020 | 18 | 2020 |
| Targeting neratinib-induced diarrhea with budesonide and colesevelam in a rat model KR Secombe, IA Ball, J Shirren, AD Wignall, J Finnie, D Keefe, ... Cancer chemotherapy and pharmacology 83 (3), 531-543, 2019 | 14 | 2019 |
| Guidelines for reporting on animal fecal transplantation (GRAFT) studies: recommendations from a systematic review of murine transplantation protocols KR Secombe, GH Al-Qadami, CB Subramaniam, JM Bowen, J Scott, ... Gut microbes 13 (1), 1979878, 2021 | 11 | 2021 |
| Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report JK Coller, JM Bowen, IA Ball, HR Wardill, YZA van Sebille, ... Cancer chemotherapy and pharmacology 79 (2), 431-434, 2017 | 9 | 2017 |
| A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options HR Wardill, RJ Gibson, YZA Van Sebille, KR Secombe, RM Logan, ... Experimental Biology and Medicine 241 (13), 1386-1394, 2016 | 9 | 2016 |
| The GLP-2 analogue elsiglutide reduces diarrhoea caused by the tyrosine kinase inhibitor lapatinib in rats BJ Mayo, KR Secombe, AD Wignall, E Bateman, D Thorpe, C Pietra, ... Cancer chemotherapy and pharmacology 85 (4), 793-803, 2020 | 8 | 2020 |
| Budesonide reduces neratinib-induced gastrointestinal injury and diarrhoea in rats KR Secombe, IA Ball, J Shirren, AD Wignall, HR Wardill, YZA Van Sebille, ... ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 13, 74-74, 2017 | 3 | 2017 |
| Pathophysiology of neratinib-induced diarrhea in male and female rats: microbial alterations a potential determinant KR Secombe, IA Ball, J Shirren, AD Wignall, DM Keefe, JM Bowen Breast Cancer 28 (1), 99-109, 2021 | 2 | 2021 |
| Pre-treatment Blautia abundance regulates chemotherapy-induced gastrointestinal toxicity risk: a pilot study K Secombe, J Bowen, J Coller, R Gibson, A Stringer, N Al-Dasooqi, ... ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 14, 59-59, 2018 | 2 | 2018 |
| Epithelial-specific TLR4 knockout challenges current evidence of TLR4 homeostatic control of gut permeability EE Crame, JM Bowen, KR Secombe, JK Coller, M François, W Leifert, ... Inflammatory Intestinal Diseases 6 (4), 199-209, 2021 | 1 | 2021 |
| Baseline gut microbiota composition is associated with oral mucositis and tumour recurrence in patients with head and neck cancer: a pilot study G Al-Qadami, J Bowen, Y Van Sebille, K Secombe, M Dorraki, J Verjans, ... | | 2022 |
| Antibiotic treatment targeting gram negative bacteria prevents neratinib-induced diarrhea in rats KR Secombe, IA Ball, AD Wignall, E Bateman, DM Keefe, JM Bowen Neoplasia 30, 100806, 2022 | | 2022 |
| Intestinal toll-like receptor 4 knockout alters the functional capacity of the gut microbiome following irinotecan treatment KR Secombe, EE Crame, JSY Tam, HR Wardill, RJ Gibson, JK Coller, ... Cancer Chemotherapy and Pharmacology 89 (2), 275-281, 2022 | | 2022 |
| Using patient-reported outcome measures to determine the role of the microbiome in cancer treatment-induced diarrhoea K Secombe, I Ball, C Subramaniam, G Al-Qadami, J Bowen, HR Wardill ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 17, 174-175, 2021 | | 2021 |
| 200| Intestinal epithelial TLR4 are crucial to chemotherapy toxicity development E Crame, HR Wardill, K Secombe, J Coller, J Bowen | | 2021 |
