Furoxans (1,2,5-Oxadiazole-N-Oxides) as Novel NO Mimetic Neuroprotective and Procognitive Agents IT Schiefer, L VandeVrede, M Fa’, O Arancio, GRJ Thatcher Journal of medicinal chemistry 55 (7), 3076-3087, 2012 | 100 | 2012 |
Benzothiophene selective estrogen receptor modulators provide neuroprotection by a novel GPR30-dependent mechanism R Abdelhamid, J Luo, L VandeVrede, I Kundu, B Michalsen, VA Litosh, ... ACS chemical neuroscience 2 (5), 256-268, 2011 | 88 | 2011 |
The effect of electronic-cigarette vaping on cardiac function and angiogenesis in mice H Shi, X Fan, A Horton, ST Haller, DJ Kennedy, IT Schiefer, L Dworkin, ... Scientific reports 9 (1), 4085, 2019 | 75 | 2019 |
Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate transporters and α-7 nicotinic acetylcholine receptor in female CD-1 mice F Alasmari, LE Crotty Alexander, JA Nelson, IT Schiefer, E Breen, ... Progress in Neuro-Psychopharmacology & Biological Psychiatry 77, 1-8, 2017 | 62 | 2017 |
Proteasome activation is a mechanism for pyrazolone small molecules displaying therapeutic potential in amyotrophic lateral sclerosis PC Trippier, KT Zhao, SG Fox, IT Schiefer, R Benmohamed, J Moran, ... ACS chemical neuroscience 5 (9), 823-829, 2014 | 50 | 2014 |
Proteomic and Mass Spectroscopic Quantitation of Protein S-Nitrosation Differentiates NO-Donors V Sinha, GT Wijewickrama, REP Chandrasena, H Xu, PD Edirisinghe, ... ACS chemical biology 5 (7), 667-680, 2010 | 47 | 2010 |
Development of a reactive oxygen species-sensitive nitric oxide synthase inhibitor for the treatment of ischemic stroke KM Nash, IT Schiefer, ZA Shah Free Radical Biology and Medicine 115, 395-404, 2018 | 40 | 2018 |
Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors IT Schiefer, S Tapadar, V Litosh, M Siklos, R Scism, GT Wijewickrama, ... Journal of medicinal chemistry 56 (15), 6054-6068, 2013 | 38 | 2013 |
Novel selective calpain 1 inhibitors as potential therapeutics in Alzheimer’s disease M Fa, H Zhang, A Staniszewski, F Saeed, LW Shen, IT Schiefer, MI Siklos, ... Journal of Alzheimer's Disease 49 (3), 707-721, 2016 | 31 | 2016 |
Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates IT Schiefer, S Abdul-Hay, H Wang, M Vanni, Z Qin, GRJ Thatcher Journal of medicinal chemistry 54 (7), 2293-2306, 2011 | 29 | 2011 |
Identification of a gut commensal that compromises the blood pressure-lowering effect of ester angiotensin-converting enzyme inhibitors T Yang, X Mei, E Tackie-Yarboi, MT Akere, J Kyoung, B Mell, JY Yeo, ... Hypertension 79 (8), 1591-1601, 2022 | 24 | 2022 |
Quantification of phenolic acid metabolites in humans by LC–MS: A structural and targeted metabolomics approach ME Obrenovich, CJ Donskey, IT Schiefer, R Bongiovanni, L Li, GE Jaskiw Bioanalysis 10 (19), 1591-1608, 2018 | 24 | 2018 |
NO-SSRIs: nitric oxide chimera drugs incorporating a selective serotonin reuptake inhibitor S Abdul-Hay, IT Schiefer, REP Chandrasena, M Li, R Abdelhamid, ... ACS medicinal chemistry letters 2 (9), 656-661, 2011 | 24 | 2011 |
Furoxans (Oxadiazole-4N-oxides) with Attenuated Reactivity are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory A Horton, K Nash, E Tackie-Yarboi, A Kostrevski, A Novak, A Raghavan, ... Journal of medicinal chemistry 61 (10), 4593-4607, 2018 | 21 | 2018 |
E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically … F Alasmari, LEC Alexander, AM Hammad, A Horton, H Alhaddad, ... Chemico-biological interactions 333, 109308, 2021 | 19 | 2021 |
Pharmacokinetics and pharmacodynamics of nitric oxide mimetic agents A Horton, IT Schiefer Nitric Oxide 84, 69-78, 2019 | 18 | 2019 |
Combining Neurobehavioral Analysis and In Vivo Photoaffinity Labeling to Understand Protein Targets of Methamphetamine in Casper Zebrafish E Tackie-Yarboi, A Wisner, A Horton, TQT Chau, J Reigle, AJ Funk, ... ACS chemical neuroscience 11 (17), 2761-2773, 2020 | 9 | 2020 |
Identification and characterization of 5α-cyprinol-sulfating cytosolic sulfotransferases (Sults) in the zebrafish (Danio rerio) K Kurogi, M Yoshihama, A Horton, IT Schiefer, MD Krasowski, LR Hagey, ... The Journal of steroid biochemistry and molecular biology 174, 120-127, 2017 | 7 | 2017 |
Human cytosolic sulfotransferase SULT1A3 mediates the sulfation of dextrorphan A Yamamoto, K Kurogi, IT Schiefer, MY Liu, Y Sakakibara, M Suiko, ... Biological & Pharmaceutical Bulletin 39 (9), 1432-1436, 2016 | 6 | 2016 |
Methamphetamine-induced lethal toxicity in zebrafish larvae Y Chen, AS Wisner, IT Schiefer, FE Williams, FS Hall Psychopharmacology 239 (12), 3833-3846, 2022 | 2 | 2022 |