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Isaac Schiefer
Isaac Schiefer
Verified email at utoledo.edu - Homepage
Title
Cited by
Cited by
Year
Furoxans (1,2,5-Oxadiazole-N-Oxides) as Novel NO Mimetic Neuroprotective and Procognitive Agents
IT Schiefer, L VandeVrede, M Fa’, O Arancio, GRJ Thatcher
Journal of medicinal chemistry 55 (7), 3076-3087, 2012
1002012
Benzothiophene selective estrogen receptor modulators provide neuroprotection by a novel GPR30-dependent mechanism
R Abdelhamid, J Luo, L VandeVrede, I Kundu, B Michalsen, VA Litosh, ...
ACS chemical neuroscience 2 (5), 256-268, 2011
882011
The effect of electronic-cigarette vaping on cardiac function and angiogenesis in mice
H Shi, X Fan, A Horton, ST Haller, DJ Kennedy, IT Schiefer, L Dworkin, ...
Scientific reports 9 (1), 4085, 2019
752019
Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate transporters and α-​7 nicotinic acetylcholine receptor in female CD-​1 mice
F Alasmari, LE Crotty Alexander, JA Nelson, IT Schiefer, E Breen, ...
Progress in Neuro-Psychopharmacology & Biological Psychiatry 77, 1-8, 2017
622017
Proteasome activation is a mechanism for pyrazolone small molecules displaying therapeutic potential in amyotrophic lateral sclerosis
PC Trippier, KT Zhao, SG Fox, IT Schiefer, R Benmohamed, J Moran, ...
ACS chemical neuroscience 5 (9), 823-829, 2014
502014
Proteomic and Mass Spectroscopic Quantitation of Protein S-Nitrosation Differentiates NO-Donors
V Sinha, GT Wijewickrama, REP Chandrasena, H Xu, PD Edirisinghe, ...
ACS chemical biology 5 (7), 667-680, 2010
472010
Development of a reactive oxygen species-sensitive nitric oxide synthase inhibitor for the treatment of ischemic stroke
KM Nash, IT Schiefer, ZA Shah
Free Radical Biology and Medicine 115, 395-404, 2018
402018
Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors
IT Schiefer, S Tapadar, V Litosh, M Siklos, R Scism, GT Wijewickrama, ...
Journal of medicinal chemistry 56 (15), 6054-6068, 2013
382013
Novel selective calpain 1 inhibitors as potential therapeutics in Alzheimer’s disease
M Fa, H Zhang, A Staniszewski, F Saeed, LW Shen, IT Schiefer, MI Siklos, ...
Journal of Alzheimer's Disease 49 (3), 707-721, 2016
312016
Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates
IT Schiefer, S Abdul-Hay, H Wang, M Vanni, Z Qin, GRJ Thatcher
Journal of medicinal chemistry 54 (7), 2293-2306, 2011
292011
Identification of a gut commensal that compromises the blood pressure-lowering effect of ester angiotensin-converting enzyme inhibitors
T Yang, X Mei, E Tackie-Yarboi, MT Akere, J Kyoung, B Mell, JY Yeo, ...
Hypertension 79 (8), 1591-1601, 2022
242022
Quantification of phenolic acid metabolites in humans by LC–MS: A structural and targeted metabolomics approach
ME Obrenovich, CJ Donskey, IT Schiefer, R Bongiovanni, L Li, GE Jaskiw
Bioanalysis 10 (19), 1591-1608, 2018
242018
NO-SSRIs: nitric oxide chimera drugs incorporating a selective serotonin reuptake inhibitor
S Abdul-Hay, IT Schiefer, REP Chandrasena, M Li, R Abdelhamid, ...
ACS medicinal chemistry letters 2 (9), 656-661, 2011
242011
Furoxans (Oxadiazole-4N-oxides) with Attenuated Reactivity are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory
A Horton, K Nash, E Tackie-Yarboi, A Kostrevski, A Novak, A Raghavan, ...
Journal of medicinal chemistry 61 (10), 4593-4607, 2018
212018
E-cigarette aerosols containing nicotine modulate nicotinic acetylcholine receptors and astroglial glutamate transporters in mesocorticolimbic brain regions of chronically …
F Alasmari, LEC Alexander, AM Hammad, A Horton, H Alhaddad, ...
Chemico-biological interactions 333, 109308, 2021
192021
Pharmacokinetics and pharmacodynamics of nitric oxide mimetic agents
A Horton, IT Schiefer
Nitric Oxide 84, 69-78, 2019
182019
Combining Neurobehavioral Analysis and In Vivo Photoaffinity Labeling to Understand Protein Targets of Methamphetamine in Casper Zebrafish
E Tackie-Yarboi, A Wisner, A Horton, TQT Chau, J Reigle, AJ Funk, ...
ACS chemical neuroscience 11 (17), 2761-2773, 2020
92020
Identification and characterization of 5α-cyprinol-sulfating cytosolic sulfotransferases (Sults) in the zebrafish (Danio rerio)
K Kurogi, M Yoshihama, A Horton, IT Schiefer, MD Krasowski, LR Hagey, ...
The Journal of steroid biochemistry and molecular biology 174, 120-127, 2017
72017
Human cytosolic sulfotransferase SULT1A3 mediates the sulfation of dextrorphan
A Yamamoto, K Kurogi, IT Schiefer, MY Liu, Y Sakakibara, M Suiko, ...
Biological & Pharmaceutical Bulletin 39 (9), 1432-1436, 2016
62016
Methamphetamine-induced lethal toxicity in zebrafish larvae
Y Chen, AS Wisner, IT Schiefer, FE Williams, FS Hall
Psychopharmacology 239 (12), 3833-3846, 2022
22022
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