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Sandrine Degryse
Sandrine Degryse
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Year
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
S Peirs, F Matthijssens, S Goossens, I Van de Walle, K Ruggero, ...
Blood, The Journal of the American Society of Hematology 124 (25), 3738-3747, 2014
2382014
Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia
C Vicente, C Schwab, M Broux, E Geerdens, S Degryse, S Demeyer, ...
Haematologica 100 (10), 1301, 2015
1702015
JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model
S Degryse, CE De Bock, L Cox, S Demeyer, O Gielen, N Mentens, ...
Blood, The Journal of the American Society of Hematology 124 (20), 3092-3100, 2014
1522014
HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development
CE de Bock, S Demeyer, S Degryse, D Verbeke, B Sweron, O Gielen, ...
Cancer discovery 8 (5), 616-631, 2018
1012018
Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia
S Degryse, CE De Bock, S Demeyer, I Govaerts, S Bornschein, D Verbeke, ...
Leukemia 32 (3), 788-800, 2018
842018
Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes
A Zaitsev, M Chelushkin, D Dyikanov, I Cheremushkin, B Shpak, K Nomie, ...
Cancer Cell 40 (8), 879-894. e16, 2022
542022
Distinct acute lymphoblastic leukemia (ALL)-associated Janus kinase 3 (JAK3) mutants exhibit different cytokine-receptor requirements and JAK inhibitor specificities
E Losdyck, T Hornakova, L Springuel, S Degryse, O Gielen, J Cools, ...
Journal of Biological Chemistry 290 (48), 29022-29034, 2015
492015
Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors
A Dagklis, S Demeyer, J De Bie, E Radaelli, D Pauwels, S Degryse, ...
Blood, The Journal of the American Society of Hematology 128 (23), 2642-2654, 2016
482016
JAK kinase inhibitors for the treatment of acute lymphoblastic leukemia
S Degryse, J Cools
Journal of hematology & oncology 8, 1-5, 2015
392015
Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL
S Degryse, S Bornschein, CE de Bock, E Leroy, M Vanden Bempt, ...
Blood, The Journal of the American Society of Hematology 131 (4), 421-425, 2018
352018
Tadalafil enhances immune signatures in response to neoadjuvant nivolumab in resectable head and neck squamous cell carcinoma
AJ Luginbuhl, JM Johnson, LA Harshyne, AJ Linnenbach, SK Shukla, ...
Clinical Cancer Research 28 (5), 915-927, 2022
272022
HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development. Cancer Discov. 2018; 8: 616–631. doi: 10.1158/2159-8290
CE De Bock, S Demeyer, S Degryse, D Verbeke, B Sweron, O Gielen, ...
CD-17-0583.[Abstract][CrossRef][Google Scholar], 0
15
B-Cell Infiltrate in the Tumor Microenvironment Is Associated With Improved Survival in Resected Lung Adenocarcinoma
I Dagogo-Jack, I Valiev, N Kotlov, A Belozerova, A Lopareva, A Butusova, ...
JTO Clinical and Research Reports 4 (7), 100527, 2023
12023
Correlative biomarkers for CART19 response in patients with relapsed or refractory diffuse large B-cell lymphoma
CL Batlevi, G Nos, N Kotlov, M Sorokina, M Okwali, A Bagaev, L Michaud, ...
Blood 140 (Supplement 1), 9228-9230, 2022
12022
B cell content in the tumor microenvironment is associated with improved survival in stage II lung adenocarcinoma
I Valiev, N Kotlov, A Belozerova, A Lopareva, A Butusova, N Samarina, ...
Cancer Research 82 (12_Supplement), 5172-5172, 2022
12022
Predictors of treatment response in a preoperative window of opportunity trial of nivolumab in resectable squamous cell carcinoma of the head and neck
N Kotlov, Z Antysheva, D Antonova, N Samarina, S Degryse, ...
Cancer Research 81 (13_Supplement), 1441-1441, 2021
12021
Synergism Between HOXA9 and Mutant JAK3 (M511I) Leads to Rapid Leukemia Development within an in Vivo Murine Bone Marrow Transplant Model
CE de Bock, S Degryse, S Demeyer, B Sweron, O Gielen, N Mentens, ...
Blood 124 (21), 1078, 2014
12014
Gastric Cancer Tumor Immune Microenvironment Landscape: Clinical Implications for Patient Outcome and Response to PD-1 Immune Checkpoint Blockade
M Shah, S Sarkar, D Melikhova, P Thakkar, O Kudryashova, N Shin, ...
2024
ML quantification of tumor-Infiltrating lymphocytes distinguishes immune-phenotypes and reveals phenotypic heterogeneity
N Le, B Rahsepar, J Hipp, J Conway, Y Gerardin, E Krause, C Shen, ...
Cancer Research 84 (6_Supplement), 905-905, 2024
2024
Novel genomic alterations and transcriptomic-based tumor microenvironment classification of sarcoma and their impact on treatment decision making.
I Zhuk, A Novokreschchenova, A Aukhadieva, S Degryse, A Shevkoplias, ...
Journal of Clinical Oncology 41 (16_suppl), 11547-11547, 2023
2023
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Articles 1–20