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Gerry P Crossan
Gerry P Crossan
Group Leader MRC Laboratory of Molecular Biology
Verified email at mrc-lmb.cam.ac.uk
Title
Cited by
Cited by
Year
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
F Langevin, GP Crossan, IV Rosado, MJ Arends, KJ Patel
Nature 475 (7354), 53-58, 2011
5372011
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function
JI Garaycoechea, GP Crossan, F Langevin, M Daly, MJ Arends, KJ Patel
Nature 489 (7417), 571-575, 2012
4042012
Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells
JI Garaycoechea, GP Crossan, F Langevin, L Mulderrig, S Louzada, ...
Nature 553 (7687), 171, 2018
3612018
Endogenous formaldehyde is a hematopoietic stem cell genotoxin and metabolic carcinogen
LB Pontel, IV Rosado, G Burgos-Barragan, JI Garaycoechea, R Yu, ...
Molecular cell 60 (1), 177-188, 2015
3352015
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia
GP Crossan, L van der Weyden, IV Rosado, F Langevin, PHL Gaillard, ...
Nature genetics 43 (2), 147-152, 2011
2402011
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway
IV Rosado, F Langevin, GP Crossan, M Takata, KJ Patel
Nature structural & molecular biology 18 (12), 1432-1434, 2011
2062011
Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair
MRG Hodskinson, J Silhan, GP Crossan, JI Garaycoechea, S Mukherjee, ...
Molecular cell 54 (3), 472-484, 2014
1612014
The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA
GP Crossan, KJ Patel
The Journal of pathology 226 (2), 326-337, 2012
1422012
Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response
L Mulderrig, JI Garaycoechea, ZK Tuong, CL Millington, FA Dingler, ...
Nature 600 (7887), 158-163, 2021
752021
Maternal aldehyde elimination during pregnancy preserves the fetal genome
N Oberbeck, F Langevin, G King, N de Wind, GP Crossan, KJ Patel
Molecular cell 55 (6), 807-817, 2014
662014
Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity
C Umansky, AE Morellato, M Rieckher, MA Scheidegger, MR Martinefski, ...
Nature Communications 13 (1), 745, 2022
472022
Analysis of the novel fanconi anemia gene SLX4/FANCP in familial breast cancer cases
JL Bakker, SE van Mil, G Crossan, N Sabbaghian, K De Leeneer, ...
Human mutation 34 (1), 70-73, 2013
362013
DNA cross-link repair safeguards genomic stability during premeiotic germ cell development
RJ Hill, GP Crossan
Nature genetics 51 (8), 1283-1294, 2019
312019
Do mutational dynamics in stem cells explain the origin of common cancers?
GP Crossan, JI Garaycoechea, KJ Patel
Cell stem cell 16 (2), 111-112, 2015
92015
GCNA is a histone binding protein required for spermatogonial stem cell maintenance
J Ribeiro, GP Crossan
bioRxiv, 2022.02. 21.481287, 2022
42022
“Ring-fencing” BRCA1 tumor suppressor activity
KJ Patel, GP Crossan, MRG Hodskinson
Cancer cell 20 (6), 693-695, 2011
42011
Metformin: treating the cause of Fanconi anemia?
GP Crossan
Blood 128 (24), 2748-2750, 2016
32016
Aldehydes and Fanconi anaemia: the enemy within
FP Langevin, JI Garaycoechea, GP Crossan, KJ Patel
Medecine sciences: M/S 29 (4), 361-364, 2013
22013
The Fanconi Pathway Counteracts the Toxic Effects of Naturally Produced Aldehydes
G Crossan, FP Langevin, MJ Arends, KJ Patel
The Journal of Pathology 226 (1), S5, 2012
12012
Aldéhydes et anémie de Fanconi-L’ennemi de l’intérieur
FPM Langevin, JI Garaycoechea, GP Crossan, KJ Patel
médecine/sciences 29 (4), 361-364, 2013
2013
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