Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial SA Harrison, MR Bashir, CD Guy, R Zhou, CA Moylan, JP Frias, ... The Lancet 394 (10213), 2012-2024, 2019 | 547 | 2019 |
Relationship between methylome and transcriptome in patients with nonalcoholic fatty liver disease SK Murphy, H Yang, CA Moylan, H Pang, A Dellinger, MF Abdelmalek, ... Gastroenterology 145 (5), 1076-1087, 2013 | 376 | 2013 |
Disparities in liver transplantation before and after introduction of the MELD score CA Moylan, CW Brady, JL Johnson, AD Smith, JE Tuttle-Newhall, AJ Muir Jama 300 (20), 2371-2378, 2008 | 355 | 2008 |
Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease CA Moylan, H Pang, A Dellinger, A Suzuki, ME Garrett, CD Guy, ... Hepatology 59 (2), 471-482, 2014 | 304 | 2014 |
Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis WK Syn, SS Choi, E Liaskou, GF Karaca, KM Agboola, YH Oo, Z Mi, ... Hepatology 53 (1), 106-115, 2011 | 289 | 2011 |
Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis SS Choi, A Omenetti, RP Witek, CA Moylan, WK Syn, Y Jung, L Yang, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (6 …, 2009 | 265 | 2009 |
Hedgehog controls hepatic stellate cell fate by regulating metabolism Y Chen, SS Choi, GA Michelotti, IS Chan, M Swiderska-Syn, GF Karaca, ... Gastroenterology 143 (5), 1319-1329. e11, 2012 | 256 | 2012 |
Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway SS Choi, WK Syn, GF Karaca, A Omenetti, CA Moylan, RP Witek, ... Journal of Biological Chemistry 285 (47), 36551-36560, 2010 | 221 | 2010 |
Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer GM Philips, IS Chan, M Swiderska, VT Schroder, C Guy, GF Karaca, ... PloS one 6 (9), e23943, 2011 | 194 | 2011 |
Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma T de Almeida Pereira, RP Witek, WK Syn, SS Choi, S Bradrick, GF Karaca, ... Laboratory investigation 90 (12), 1690-1703, 2010 | 137 | 2010 |
Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer CR Acharya, DS Hsu, CK Anders, A Anguiano, KH Salter, KS Walters, ... Jama 299 (13), 1574-1587, 2008 | 137 | 2008 |
Glycemic control predicts severity of hepatocyte ballooning and hepatic fibrosis in nonalcoholic fatty liver disease AS Alexopoulos, MJ Crowley, Y Wang, CA Moylan, CD Guy, R Henao, ... Hepatology 74 (3), 1220-1233, 2021 | 74 | 2021 |
Association between magnetic resonance imaging–proton density fat fraction and liver histology features in patients with nonalcoholic fatty liver disease or nonalcoholic … B Wildman-Tobriner, MM Middleton, CA Moylan, S Rossi, O Flores, ... Gastroenterology 155 (5), 1428-1435. e2, 2018 | 73 | 2018 |
Serum interleukin‐8, osteopontin, and monocyte chemoattractant protein 1 are associated with hepatic fibrosis in patients with nonalcoholic fatty liver disease O Glass, R Henao, K Patel, CD Guy, HJ Gruss, WK Syn, CA Moylan, ... Hepatology communications 2 (11), 1344-1355, 2018 | 72 | 2018 |
Nonalcoholic fatty liver disease: key considerations before and after liver transplantation YA Patel, CL Berg, CA Moylan Digestive diseases and sciences 61, 1406-1416, 2016 | 69 | 2016 |
Increased glutaminolysis marks active scarring in nonalcoholic steatohepatitis progression K Du, SK Chitneni, A Suzuki, Y Wang, R Henao, J Hyun, RT Premont, ... Cellular and molecular gastroenterology and hepatology 10 (1), 1-21, 2020 | 64 | 2020 |
Activation of Rac1 promotes hedgehog‐mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells SS Choi, RP Witek, L Yang, A Omenetti, WK Syn, CA Moylan, Y Jung, ... Hepatology 52 (1), 278-290, 2010 | 62 | 2010 |
Vitamin D is not associated with severity in NAFLD: results of a paired clinical and gene expression profile analysis YA Patel, R Henao, CA Moylan, CD Guy, DL Piercy, AM Diehl, ... Official journal of the American College of Gastroenterology| ACG 111 (11 …, 2016 | 60 | 2016 |
Relationship of nonalcoholic fatty liver disease and heart failure with preserved ejection fraction HM Salah, A Pandey, A Soloveva, MF Abdelmalek, AM Diehl, CA Moylan, ... Basic to Translational Science 6 (11), 918-932, 2021 | 54 | 2021 |
Nonalcoholic fatty liver disease and risk of heart failure among medicare beneficiaries M Fudim, L Zhong, KV Patel, R Khera, MF Abdelmalek, AM Diehl, ... Journal of the American Heart Association 10 (22), e021654, 2021 | 51 | 2021 |