EZH2 and KDM6A Act as an Epigenetic Switch to Regulate Mesenchymal Stem Cell Lineage Specification S Hemming, D Cakouros, S Isenmann, L Cooper, D Menicanin, ... Stem cells 32 (3), 802-815, 2014 | 297 | 2014 |
The role of cytochrome c in caspase activation in Drosophila melanogaster cells L Dorstyn, S Read, D Cakouros, JR Huh, BA Hay, S Kumar The Journal of cell biology 156 (6), 1089-1098, 2002 | 241 | 2002 |
A tumor suppressor function for caspase-2 LH Ho, R Taylor, L Dorstyn, D Cakouros, P Bouillet, S Kumar Proceedings of the National Academy of Sciences 106 (13), 5336-5341, 2009 | 192 | 2009 |
Twist-1 Induces Ezh2 Recruitment Regulating Histone Methylation along the Ink4A/Arf Locus in Mesenchymal Stem Cells D Cakouros, S Isenmann, L Cooper, A Zannettino, P Anderson, C Glackin, ... Molecular and cellular biology 32 (8), 1433-1441, 2012 | 130 | 2012 |
Ecdysone-induced expression of the caspase DRONC during hormone-dependent programmed cell death in Drosophila is regulated by Broad-Complex D Cakouros, T Daish, D Martin, EH Baehrecke, S Kumar The Journal of cell biology 157 (6), 985-996, 2002 | 111 | 2002 |
Ecdysone receptor directly binds the promoter of the Drosophila caspase dronc, regulating its expression in specific tissues D Cakouros, TJ Daish, S Kumar The Journal of cell biology 165 (5), 631-640, 2004 | 107 | 2004 |
Transcriptional control of the core cell-death machinery S Kumar, D Cakouros Trends in biochemical sciences 29 (4), 193-199, 2004 | 86 | 2004 |
Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination D Cakouros, S Hemming, K Gronthos, R Liu, A Zannettino, S Shi, ... Epigenetics & chromatin 12, 1-20, 2019 | 79 | 2019 |
Identification of novel EZH2 targets regulating osteogenic differentiation in mesenchymal stem cells S Hemming, D Cakouros, K Vandyke, MJ Davis, ACW Zannettino, ... Stem cells and development 25 (12), 909-921, 2016 | 79 | 2016 |
Epigenetic regulation of bone marrow stem cell aging: revealing epigenetic signatures associated with hematopoietic and mesenchymal stem cell aging D Cakouros, S Gronthos Aging and disease 10 (1), 174, 2019 | 66 | 2019 |
Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells ZE Kilpatrick, D Cakouros, S Kumar Journal of Biological Chemistry 280 (12), 11981-11986, 2005 | 65 | 2005 |
EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture and structural integrity and accelerates remodeling S Hemming, D Cakouros, J Codrington, K Vandyke, A Arthur, ... The FASEB Journal 31 (3), 1011-1027, 2017 | 62 | 2017 |
UTX coordinates steroid hormone-mediated autophagy and cell death D Denton, MT Aung-Htut, N Lorensuhewa, S Nicolson, W Zhu, K Mills, ... Nature communications 4 (1), 2916, 2013 | 55 | 2013 |
A NF-κB/Sp1 region is essential for chromatin remodeling and correct transcription of a human granulocyte-macrophage colony-stimulating factor transgene D Cakouros, PN Cockerill, AG Bert, R Mital, DC Roberts, MF Shannon The Journal of Immunology 167 (1), 302-310, 2001 | 48 | 2001 |
Twist‐ing cell fate: Mechanistic insights into the role of twist in lineage specification/differentiation and tumorigenesis D Cakouros, RM Raices, S Gronthos, CA Glackin Journal of cellular biochemistry 110 (6), 1288-1298, 2010 | 46 | 2010 |
Distinct promoter regions regulate spatial and temporal expression of the Drosophila caspase dronc TJ Daish, D Cakouros, S Kumar Cell Death & Differentiation 10 (12), 1348-1356, 2003 | 43 | 2003 |
An arginine-histone methyltransferase, CARMER, coordinates ecdysone-mediated apoptosis in Drosophila cells D Cakouros, TJ Daish, K Mills, S Kumar Journal of Biological Chemistry 279 (18), 18467-18471, 2004 | 42 | 2004 |
Epigenetic regulators of mesenchymal stem/stromal cell lineage determination D Cakouros, S Gronthos Current osteoporosis reports 18, 597-605, 2020 | 38 | 2020 |
Nuclear factor of activated T cells contributes to the function of the CD28 response region of the granulocyte macrophage-colony stimulating factor promoter C Shang, J Attema, D Cakouros, PN Cockerill, MF Shannon International immunology 11 (12), 1945-1956, 1999 | 36 | 1999 |
Novel basic helix–loop–helix transcription factor Hes4 antagonizes the function of twist-1 to regulate lineage commitment of bone marrow stromal/stem cells D Cakouros, S Isenmann, SE Hemming, D Menicanin, E Camp, ... Stem cells and development 24 (11), 1297-1308, 2015 | 35 | 2015 |