| Clostridium difficile infection WK Smits, D Lyras, DB Lacy, MH Wilcox, EJ Kuijper Nature reviews Disease primers 2 (1), 1-20, 2016 | 964 | 2016 |
| Toxin B is essential for virulence of Clostridium difficile D Lyras, JR O’Connor, PM Howarth, SP Sambol, GP Carter, ... Nature 458 (7242), 1176-1179, 2009 | 951 | 2009 |
| Expansion of the Clostridium perfringens toxin-based typing scheme JI Rood, V Adams, J Lacey, D Lyras, BA McClane, SB Melville, RJ Moore, ... Anaerobe 53, 5-10, 2018 | 540 | 2018 |
| Epidemics of Diarrhea Caused by a Clindamycin-Resistant Strain of Clostridium difficile in Four Hospitals S Johnson, MH Samore, KA Farrow, GE Killgore, FC Tenover, D Lyras, ... New England Journal of Medicine 341 (22), 1645-1651, 1999 | 476 | 1999 |
| Translocation and dissemination of commensal bacteria in post-stroke infection D Stanley, LJ Mason, KE Mackin, YN Srikhanta, D Lyras, MD Prakash, ... Nature medicine 22 (11), 1277-1284, 2016 | 402 | 2016 |
| Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation SL Masters, V Lagou, I Jéru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ... Science translational medicine 8 (332), 332ra45-332ra45, 2016 | 314 | 2016 |
| Defining the roles of TcdA and TcdB in localized gastrointestinal disease, systemic organ damage, and the host response during Clostridium difficile infections GP Carter, A Chakravorty, TA Pham Nguyen, S Mileto, F Schreiber, L Li, ... MBio 6 (3), 10.1128/mbio. 00551-15, 2015 | 271 | 2015 |
| Influence of gastric acid on susceptibility to infection with ingested bacterial pathogens SM Tennant, EL Hartland, T Phumoonna, D Lyras, JI Rood, ... Infection and immunity 76 (2), 639-645, 2008 | 237 | 2008 |
| Clostridium difficile virulence factors: Insights into an anaerobic spore-forming pathogen MM Awad, PA Johanesen, GP Carter, E Rose, D Lyras Gut microbes 5 (5), 579-593, 2014 | 218 | 2014 |
| Binary Toxin Production in Clostridium difficile Is Regulated by CdtR, a LytTR Family Response Regulator GP Carter, D Lyras, DL Allen, KE Mackin, PM Howarth, JR O'Connor, ... Journal of bacteriology 189 (20), 7290-7301, 2007 | 217 | 2007 |
| The antimicrobial potential of cannabidiol MAT Blaskovich, AM Kavanagh, AG Elliott, B Zhang, S Ramu, M Amado, ... Communications biology 4 (1), 1-18, 2021 | 204 | 2021 |
| The role of toxin A and toxin B in the virulence of Clostridium difficile GP Carter, JI Rood, D Lyras Trends in microbiology 20 (1), 21-29, 2012 | 199 | 2012 |
| The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile GP Carter, GR Douce, R Govind, PM Howarth, KE Mackin, J Spencer, ... PLoS pathogens 7 (10), e1002317, 2011 | 194 | 2011 |
| Construction and analysis of chromosomal Clostridium difficile mutants JR O'Connor, D Lyras, KA Farrow, V Adams, DR Powell, J Hinds, ... Molecular microbiology 61 (5), 1335-1351, 2006 | 194 | 2006 |
| The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia CA Cowardin, EL Buonomo, MM Saleh, MG Wilson, SL Burgess, ... Nature microbiology 1 (8), 1-10, 2016 | 193 | 2016 |
| The α‐toxin of Clostridium septicum is essential for virulence CL Kennedy, EO Krejany, LF Young, JR O'Connor, MM Awad, RL Boyd, ... Molecular microbiology 57 (5), 1357-1366, 2005 | 180 | 2005 |
| Environmental Response and Autoregulation of Clostridium difficile TxeR, a Sigma Factor for Toxin Gene Expression N Mani, D Lyras, L Barroso, P Howarth, T Wilkins, JI Rood, ... Journal of bacteriology 184 (21), 5971-5978, 2002 | 179 | 2002 |
| The role of toxin A and toxin B in Clostridium difficile-associated disease: Past and present perspectives GP Carter, JI Rood, D Lyras Gut microbes 1 (1), 58-64, 2010 | 160 | 2010 |
| Emergence of a Ribotype 244 Strain of Clostridium difficile Associated With Severe Disease and Related to the Epidemic Ribotype 027 Strain SK Lim, RL Stuart, KE Mackin, GP Carter, D Kotsanas, MJ Francis, ... Clinical Infectious Diseases 58 (12), 1723-1730, 2014 | 156 | 2014 |
| Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β ML Kim, JJ Chae, YH Park, D De Nardo, RA Stirzaker, HJ Ko, H Tye, ... Journal of Experimental Medicine 212 (6), 927-938, 2015 | 147 | 2015 |
