| NAD+ cleavage activity by animal and plant TIR domains in cell death pathways S Horsefield, H Burdett, X Zhang, MK Manik, Y Shi, J Chen, T Qi, J Gilley, ... Science 365 (6455), 793-799, 2019 | 396 | 2019 |
| SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration MD Figley, W Gu, JD Nanson, Y Shi, Y Sasaki, K Cunnea, AK Malde, X Jia, ... Neuron 109 (7), 1118-1136. e11, 2021 | 197 | 2021 |
| Cyclic ADP ribose isomers: production, chemical structures, and immune signaling MK Manik, Y Shi, S Li, MA Zaydman, N Damaraju, S Eastman, TG Smith, ... Science 377 (6614), eadc8969, 2022 | 71* | 2022 |
| Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules Y Shi, PS Kerry, JD Nanson, T Bosanac, Y Sasaki, R Krauss, FK Saikot, ... Molecular cell 82 (9), 1643-1659. e10, 2022 | 71 | 2022 |
| MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography MTB Clabbers, S Holmes, TW Muusse, PR Vajjhala, SJ Thygesen, ... Nature communications 12 (1), 2578, 2021 | 67 | 2021 |
| Death, TIR, and RHIM: self-assembling domains involved in innate immunity and cell-death signaling JD Nanson, B Kobe, T Ve Journal of Leukocyte Biology 105 (2), 363-375, 2019 | 48 | 2019 |
| Structural basis for nuclear import selectivity of pioneer transcription factor SOX2 B Jagga, M Edwards, M Pagin, KM Wagstaff, D Aragão, N Roman, ... Nature communications 12 (1), 28, 2021 | 31 | 2021 |
| Structural evolution of TIR-domain signalosomes S Nimma, W Gu, N Maruta, Y Li, M Pan, FK Saikot, BYJ Lim, ... Frontiers in Immunology 12, 784484, 2021 | 30 | 2021 |
| Structure, function, and regulation of thioesterases CMD Swarbrick, JD Nanson, EI Patterson, JK Forwood Progress in Lipid Research 79, 101036, 2020 | 26 | 2020 |
| Structural basis for regulation of the human acetyl-CoA thioesterase 12 and interactions with the steroidogenic acute regulatory protein-related lipid transfer (START) domain CMD Swarbrick, N Roman, N Cowieson, EI Patterson, J Nanson, ... Journal of Biological Chemistry 289 (35), 24263-24274, 2014 | 25 | 2014 |
| Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis JD Nanson, Z Himiari, CMD Swarbrick, JK Forwood Scientific Reports 5 (1), 14797, 2015 | 24 | 2015 |
| Regulation of signaling by cooperative assembly formation in mammalian innate immunity signalosomes by molecular mimics JD Nanson, MH Rahaman, T Ve, B Kobe Seminars in Cell & Developmental Biology 99, 96-114, 2018 | 21 | 2018 |
| Structural Characterisation of FabG from Yersinia pestis, a Key Component of Bacterial Fatty Acid Synthesis JD Nanson, JK Forwood PLoS One 10 (11), e0141543, 2015 | 13 | 2015 |
| Structural characterization of a short-chain dehydrogenase/reductase from multi-drug resistant Acinetobacter baumannii EM Cross, D Aragão, KM Smith, KI Shaw, JD Nanson, SR Raidal, ... Biochemical and biophysical research communications 518 (3), 465-471, 2019 | 8 | 2019 |
| The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs L Liu, RM Lucas, JD Nanson, Y Li, J Whitfield, JEB Curson, N Tuladhar, ... Journal of Biological Chemistry 298 (5), 2022 | 7 | 2022 |
| Crystal structure of the Toll/interleukin‐1 receptor (TIR) domain of IL‐1R10 provides structural insights into TIR domain signalling S Nimma, W Gu, MK Manik, T Ve, JD Nanson, B Kobe FEBS letters 596 (7), 886-897, 2022 | 6 | 2022 |
| Structural characterisation of the fatty acid biosynthesis enzyme FabF from the pathogen Listeria monocytogenes TP Soares da Costa, JD Nanson, JK Forwood Scientific Reports 7 (1), 39277, 2017 | 6 | 2017 |
| Structural characterization of β‐ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites EI Patterson, JD Nanson, J Abendroth, C Bryan, B Sankaran, PJ Myler, ... Proteins: Structure, Function, and Bioinformatics 88 (1), 47-56, 2020 | 5 | 2020 |
| Crystallization and preliminary X-ray diffraction analysis of FabG from Yersinia pestis JD Nanson, JK Forwood Acta Crystallographica Section F: Structural Biology Communications 70 (1 …, 2014 | 5 | 2014 |
| Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing W Gu, Z Luo, C Vonrhein, X Jia, T Ve, JD Nanson, B Kobe bioRxiv, 2021 | 4 | 2021 |
Bostjan KobeProfessor of Structural Biology, The University of QueenslandVerified email at uq.edu.au
