Reader in Biochemistry, University of St Andrews
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Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine, by mitochondria.
RR Ramsay, TP Singer
Journal of Biological Chemistry 261 (17), 7585-7587, 1986
Molecular enzymology of carnitine transfer and transport
RR Ramsay, RD Gandour, FR van der Leij
Biochimica et Biophysica Acta (BBA)-Protein Structure and Moleculará…, 2001
Biochemical events in the development of parkinsonism induced by 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine
TP Singer, N Castagnoli Jr, RR Ramsay, AJ Trevor
Journal of neurochemistry 49 (1), 1-8, 1987
A perspective on multi-target drug discovery and design for complex diseases
RR Ramsay, MR Popovic-Nikolic, K Nikolic, E Uliassi, ML Bolognesi
Clinical and translational medicine 7 (1), 1-14, 2018
Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism
RR Ramsay, JI Salach, J Dadgar, TP Singer
Biochemical and biophysical research communications 135 (1), 269-275, 1986
Inhibition of monoamine oxidase A by β-carboline derivatives
H Kim, SO Sablin, RR Ramsay
Archives of biochemistry and biophysics 337 (1), 137-142, 1997
Identification of 4-substituted 1, 2, 3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A
F Reck, F Zhou, M Girardot, G Kern, CJ Eyermann, NJ Hales, RR Ramsay, ...
Journal of medicinal chemistry 48 (2), 499-506, 2005
Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+
RR Ramsay, JI Salach, TP Singer
Biochemical and biophysical research communications 134 (2), 743-748, 1986
Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction
RR Ramsay, C Dunford, PK Gillman
British journal of pharmacology 152 (6), 946-951, 2007
Mechanism of the neurotoxicity of MPTP: an update
TP Singer, RR Ramsay
FEBS letters 274 (1-2), 1-8, 1990
Interaction of 1‐Methyl‐4‐Phenylpyridinium Ion (MPP+) and Its Analogs with the Rotenone/Piericidin Binding Site of NADH Dehydrogenase
RR Ramsay, MJ Krueger, SK Youngster, MR Gluck, JE Casida, TP Singer
Journal of neurochemistry 56 (4), 1184-1190, 1991
Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP
RR Ramsay, J Dadgar, A Trevor, TP Singer
Life sciences 39 (7), 581-588, 1986
The mechanism of fatty acid uptake by heart mitochondria: An acylcarnitine‐carnitine exchange
RR Ramsay, PK Tubbs
FEBS letters 54 (1), 21-25, 1975
Role of carnitine and carnitine palmitoyltransferase as integral components of the pathway for membrane phospholipid fatty acid turnover in intact human erythrocytes.
A Arduini, G Mancinelli, GL Radatti, S Dottori, F Molajoni, RR Ramsay
Journal of Biological Chemistry 267 (18), 12673-12681, 1992
The carnitine acyltransferases and their role in modulating acyl-CoA pools
RR Ramsay, A Arduini
Archives of biochemistry and biophysics 302 (2), 307-314, 1993
Carnitine acyltransferases and their influence on CoA pools in health and disease
RR Ramsay, VA Zammit
Molecular aspects of medicine 25 (5-6), 475-493, 2004
Carnitine, mitochondrial function and therapy
VA Zammit, RR Ramsay, M Bonomini, A Arduini
Advanced drug delivery reviews 61 (14), 1353-1362, 2009
The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase
RR Ramsay, AT Kowal, MK Johnson, JI Salach, TP Singer
Archives of biochemistry and biophysics 259 (2), 645-649, 1987
Assessment of enzyme inhibition: a review with examples from the development of monoamine oxidase and cholinesterase inhibitory drugs
RR Ramsay, KF Tipton
Molecules 22 (7), 1192, 2017
In vitro effects of acetaminophen metabolites and analogs on the respiration of mouse liver mitochondria
RR Ramsay, MS Rashed, SD Nelson
Archives of biochemistry and biophysics 273 (2), 449-457, 1989
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