| JTC801 induces pH-dependent death specifically in cancer cells and slows growth of tumors in mice X Song, S Zhu, Y Xie, J Liu, L Sun, D Zeng, P Wang, X Ma, G Kroemer, ... Gastroenterology 154 (5), 1480-1493, 2018 | 124 | 2018 |
| Preclinical immunoPET/CT imaging using Zr-89-labeled anti-PD-L1 monoclonal antibody for assessing radiation-induced PD-L1 upregulation in head and neck cancer and melanoma M Kikuchi, DA Clump, RM Srivastava, L Sun, D Zeng, JA Diaz-Perez, ... Oncoimmunology 6 (7), e1329071, 2017 | 104 | 2017 |
| A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N 6-methyladenosine demethylase FTO JDW Toh, L Sun, LZM Lau, J Tan, JJA Low, CWQ Tang, EJY Cheong, ... Chemical science 6 (1), 112-122, 2015 | 101 | 2015 |
| Synthesis of pyrazolo [1, 5-a][1, 3, 5] triazine derivatives as inhibitors of thymidine phosphorylase L Sun, H Bera, WK Chui European Journal of Medicinal Chemistry 65, 1-11, 2013 | 58 | 2013 |
| Folic acid-targeted etoposide cubosomes for theranostic application of cancer cell imaging and therapy Y Tian, J Li, J Zhu, N Zhu, H Zhang, L Liang, L Sun Medical Science Monitor: International Medical Journal of Experimental and …, 2017 | 51 | 2017 |
| Dual-targeted molecular imaging of cancer EB Ehlerding, L Sun, X Lan, D Zeng, W Cai Journal of Nuclear Medicine 59 (3), 390-395, 2018 | 40 | 2018 |
| Novel strategy for preparing dual-modality optical/PET imaging probes via photo-click chemistry L Sun, J Ding, W Xing, Y Gai, J Sheng, D Zeng Bioconjugate chemistry 27 (5), 1200-1204, 2016 | 39 | 2016 |
| Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo [1, 5-a][1, 3, 5] triazines as thymidine phosphorylase inhibitors L Sun, J Li, H Bera, AV Dolzhenko, GNC Chiu, WK Chui European Journal of Medicinal Chemistry 70, 400-410, 2013 | 38 | 2013 |
| Synthesis and in vitro Evaluation of 1,2,4‐Triazolo[1,5‐a][1,3,5]triazine Derivatives as Thymidine Phosphorylase Inhibitors H Bera, AV Dolzhenko, L Sun, S Dutta Gupta, WK Chui Chemical Biology & Drug Design 82 (3), 351-360, 2013 | 35 | 2013 |
| Synthesis, anti-thymidine phosphorylase activity and molecular docking of 5-thioxo-[1, 2, 4] triazolo [1, 5-a][1, 3, 5] triazin-7-ones H Bera, MH Lee, L Sun, AV Dolzhenko, WK Chui Bioorganic Chemistry 50, 34-40, 2013 | 34 | 2013 |
| A structure–activity relationship study of 1, 2, 4-triazolo [1, 5-a][1, 3, 5] triazin-5, 7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti … H Bera, BJ Tan, L Sun, AV Dolzhenko, WK Chui, GNC Chiu European Journal of Medicinal Chemistry 67, 325-334, 2013 | 34 | 2013 |
| A multi-functional polymeric carrier for simultaneous positron emission tomography imaging and combination therapy J Sun, L Sun, J Li, J Xu, Z Wan, Z Ouyang, L Liang, S Li, D Zeng Acta biomaterialia 75, 312-322, 2018 | 33 | 2018 |
| Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: Synthesis, pharmacological evaluation and molecular docking study of 2-thioxo … H Bera, P kumar Ojha, BJ Tan, L Sun, AV Dolzhenko, WK Chui, GNC Chiu European journal of medicinal chemistry 78, 294-303, 2014 | 30 | 2014 |
| New Bifunctional Chelator p-SCN-PhPr-NE3TA for Copper-64: Synthesis, Peptidomimetic Conjugation, Radiolabeling, and Evaluation for PET Imaging Y Gai, L Sun, W Hui, Q Ouyang, CJ Anderson, G Xiang, X Ma, D Zeng Inorganic chemistry 55 (14), 6892-6901, 2016 | 28 | 2016 |
| Synthesis and evaluation of a dipeptide–drug conjugate library as substrates for PEPT1 L Zhang, L Zhang, T Luo, J Zhou, L Sun, Y Xu ACS Combinatorial Science 14 (2), 108-114, 2012 | 24 | 2012 |
| Synthesis, in vitro evaluation of thymidine phosphorylase inhibitory activity, and in silico study of 1, 3, 5-triazin-2, 4-dione and its fused analogues H Bera, WK Chui, SD Gupta, AV Dolzhenko, L Sun Medicinal Chemistry Research 22, 6010-6021, 2013 | 20 | 2013 |
| Universal molecular scaffold for facile construction of multivalent and multimodal imaging probes Y Gai, G Xiang, X Ma, W Hui, Q Ouyang, L Sun, J Ding, J Sheng, D Zeng Bioconjugate chemistry 27 (3), 515-520, 2016 | 19 | 2016 |
| Highly-efficient and versatile fluorous-tagged Cu (i)-catalyzed azide–alkyne cycloaddition ligand for preparing bioconjugates L Sun, Y Gai, CJ Anderson, D Zeng Chemical communications 51 (96), 17072-17075, 2015 | 18 | 2015 |
| In vitro biologic efficacy of sunitinib drug-eluting beads on human colorectal and hepatocellular carcinoma—A pilot study S Lahti, JM Ludwig, M Xing, L Sun, D Zeng, HS Kim PLoS One 12 (4), e0174539, 2017 | 15 | 2017 |
| Targeted Yttrium 89-Doxorubicin Drug-Eluting Bead A Safety and Feasibility Pilot Study in a Rabbit Liver Cancer Model JM Ludwig, M Xing, Y Gai, L Sun, D Zeng, HS Kim Molecular pharmaceutics 14 (8), 2824-2830, 2017 | 8 | 2017 |
