| hERG K+ channels: structure, function, and clinical significance JI Vandenberg, MD Perry, MJ Perrin, SA Mann, Y Ke, AP Hill Physiological reviews, 2012 | 792 | 2012 |
| Structural determinants of HERG channel block by clofilium and ibutilide M Perry, MJ de Groot, R Helliwell, D Leishman, M Tristani-Firouzi, ... Molecular pharmacology 66 (2), 240-249, 2004 | 196 | 2004 |
| Symposium review: revealing the structural basis of action of hERG potassium channel activators and blockers M Perry, M Sanguinetti, J Mitcheson The Journal of physiology 588 (17), 3157-3167, 2010 | 130 | 2010 |
| A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells H Fonoudi, H Ansari, S Abbasalizadeh, MR Larijani, S Kiani, ... Stem cells translational medicine 4 (12), 1482-1494, 2015 | 128 | 2015 |
| The low-potency, voltage-dependent HERG blocker propafenone—molecular determinants and drug trapping HJ Witchel, CE Dempsey, RB Sessions, M Perry, JT Milnes, JC Hancox, ... Molecular pharmacology 66 (5), 1201-1212, 2004 | 126 | 2004 |
| The N–terminal tail of hERG contains an amphipathic α–helix that regulates channel deactivation CA Ng, MJ Hunter, MD Perry, M Mobli, Y Ke, PW Kuchel, GF King, D Stock, ... PloS one 6 (1), e16191, 2011 | 108 | 2011 |
| Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs M Perry, PJ Stansfeld, J Leaney, C Wood, MJ De Groot, D Leishman, ... Molecular pharmacology 69 (2), 509-519, 2006 | 104 | 2006 |
| Molecular determinants of high-affinity drug binding to HERG channels. JS Mitcheson, MD Perry Current opinion in drug discovery & development 6 (5), 667-674, 2003 | 98 | 2003 |
| Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator M Perry, FB Sachse, MC Sanguinetti Proceedings of the National Academy of Sciences 104 (34), 13827-13832, 2007 | 95 | 2007 |
| PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance M Perry, FB Sachse, J Abbruzzese, MC Sanguinetti Proceedings of the National Academy of Sciences 106 (47), 20075-20080, 2009 | 71 | 2009 |
| High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants CA Ng, MD Perry, W Liang, NJ Smith, B Foo, A Shrier, GL Lukacs, AP Hill, ... Heart rhythm 17 (3), 492-500, 2020 | 65 | 2020 |
| The S4–S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating CA Ng, MD Perry, PS Tan, AP Hill, PW Kuchel, JI Vandenberg PloS one 7 (2), e31640, 2012 | 58 | 2012 |
| Altered cryptal expression of luminal potassium (BK) channels in ulcerative colitis GI Sandle, MD Perry, T Mathialahan, JE Linley, P Robinson, M Hunter, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2007 | 58 | 2007 |
| Structural determinants for high‐affinity block of hERG potassium channels J Mitcheson, M Perry, P Stansfeld, MC Sanguinetti, H Witchel, J Hancox The hERG cardiac potassium channel: Structure, function and long QT syndrome …, 2005 | 55 | 2005 |
| Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2 A Sadrieh, L Domanski, J Pitt-Francis, SA Mann, EC Hodkinson, CA Ng, ... Nature communications 5 (1), 5069, 2014 | 54 | 2014 |
| Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels PS Tan, MD Perry, CA Ng, JI Vandenberg, AP Hill Journal of General Physiology 140 (3), 293-306, 2012 | 54 | 2012 |
| Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11. 1 channels CA Ng, K Phan, AP Hill, JI Vandenberg, MD Perry Journal of Biological Chemistry 289 (37), 25822-25832, 2014 | 53 | 2014 |
| Principal role of adenylyl cyclase 6 in K+ channel regulation and vasodilator signalling in vascular smooth muscle cells CP Nelson, RD Rainbow, JL Brignell, MD Perry, JM Willets, NW Davies, ... Cardiovascular research 91 (4), 694-702, 2011 | 51 | 2011 |
| Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes SA Mann, M Imtiaz, A Winbo, A Rydberg, MD Perry, JP Couderc, ... Journal of molecular and cellular cardiology 100, 25-34, 2016 | 50 | 2016 |
| Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study STARSurg Collaborative, ... BJS open 2 (6), 400-410, 2018 | 46 | 2018 |
