Sophie Erhardt
Sophie Erhardt
Professor in Experimental Psychiatry
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Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression
LZ Agudelo, T Femenía, F Orhan, M Porsmyr-Palmertz, M Goiny, ...
Cell 159 (1), 33-45, 2014
Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia
S Erhardt, K Blennow, C Nordin, E Skogh, LH Lindström, G Engberg
Neuroscience letters 313 (1-2), 96-98, 2001
Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity
D Lindqvist, S Janelidze, P Hagell, S Erhardt, M Samuelsson, L Minthon, ...
Biological psychiatry 66 (3), 287-292, 2009
Connecting inflammation with glutamate agonism in suicidality
S Erhardt, CK Lim, KR Linderholm, S Janelidze, D Lindqvist, ...
Neuropsychopharmacology 38 (5), 743-752, 2013
Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia
KR Linderholm, E Skogh, SK Olsson, ML Dahl, M Holtze, G Engberg, ...
Schizophrenia bulletin 38 (3), 426-432, 2012
Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
TGM Van Erp, E Walton, DP Hibar, L Schmaal, W Jiang, DC Glahn, ...
Biological psychiatry 84 (9), 644-654, 2018
Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia
LK Nilsson, KR Linderholm, G Engberg, L Paulson, K Blennow, ...
Schizophrenia research 80 (2-3), 315-322, 2005
A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality
C Bay-Richter, KR Linderholm, CK Lim, M Samuelsson, ...
Brain, behavior, and immunity 43, 110-117, 2015
Endogenous kynurenic acid disrupts prepulse inhibition
S Erhardt, L Schwieler, C Emanuelsson, M Geyer
Biological psychiatry 56 (4), 255-260, 2004
The kynurenic acid hypothesis of schizophrenia
S Erhardt, L Schwieler, L Nilsson, K Linderholm, G Engberg
Physiology & behavior 92 (1-2), 203-209, 2007
Activation of brain interleukin-1β in schizophrenia
J Söderlund, J Schröder, C Nordin, M Samuelsson, L Walther-Jallow, ...
Molecular psychiatry 14 (12), 1069, 2009
Pharmacological manipulation of kynurenic acid
S Erhardt, SK Olsson, G Engberg
CNS drugs 23 (2), 91-101, 2009
Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia—significance for activation of the kynurenine pathway
L Schwieler, MK Larsson, E Skogh, ME Kegel, F Orhan, S Abdelmoaty, ...
Journal of psychiatry & neuroscience: JPN 40 (2), 126, 2015
GABA B receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo
S Erhardt, JM Mathé, K Chergui, G Engberg, TH Svensson
Naunyn-Schmiedeberg's archives of pharmacology 365 (3), 173-180, 2002
The kynurenine pathway in schizophrenia and bipolar disorder
S Erhardt, L Schwieler, S Imbeault, G Engberg
Neuropharmacology 112, 297-306, 2017
Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid
S Erhardt, G Engberg
Acta physiologica scandinavica 175 (1), 45-53, 2002
The role of inflammation in suicidal behaviour
L Brundin, S Erhardt, EY Bryleva, ED Achtyes, TT Postolache
Acta Psychiatrica Scandinavica 132 (3), 192-203, 2015
Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder
SK Olsson, M Samuelsson, P Saetre, L Lindström, EG Jönsson, C Nordin, ...
Journal of psychiatry & neuroscience: JPN 35 (3), 195, 2010
Kynurenic acid and schizophrenia
S Erhardt, L Schwieler, G Engberg
Developments in Tryptophan and Serotonin Metabolism, 155-165, 2003
Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine
S Erhardt, L Schwieler, G Engberg
Synapse 43 (4), 227-237, 2002
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